Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside

  • Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last "New Frontiers in Cardiovascular Research meeting". Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemia-reperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.

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Author:Hector A. Cabrera-Fuentes, Corina Alba-Alba, Julian Aragones, Jürgen BernhagenGND, William A. Boisvert, Hans E. Bøtker, Gabriela Cesarman-Maus, Ingrid FlemingORCiDGND, David Garcia-Dorado, Sandrine Lecour, Elisa Liehn, Michael S. Marber, Nephtali Marina, Manuel Mayr, Oscar Perez-Mendez, Tetsuji Miura, Marisol Ruiz-Meana, Eduardo M. Salinas-Estefanon, Sang-Bing Ong, Hans J. Schnittler, Jose T. Sanchez-Vega, Adriana Sumoza-Toledo, Carl-Wilhelm Vogel, Dina Yarullina, Derek M. Yellon, Klaus T. Preissner, Derek J. Hausenloy
URN:urn:nbn:de:hebis:30:3-427382
DOI:https://doi.org/10.1007/s00395-015-0527-0
ISSN:1435-1803
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/26667317
Parent Title (English):Basic research in cardiology
Publisher:Springer
Place of publication:Berlin ; Heidelberg
Document Type:Article
Language:English
Date of Publication (online):2017/01/30
Date of first Publication:2015/12/14
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2017/01/30
Tag:Atherosclerosis; Cardioprotection; Cardiovascular disease; Endothelial permeability; Extracellular RNA; High-density lipoprotein; Hypoxia; Inflammation; Ischemia/reperfusion injury; Macrophage polarization; MicroRNAs; Mitochondria; Platelet dysfunction; Vascular biology
Volume:111
Issue:(1):7
Page Number:13
First Page:1
Last Page:13
Note:
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
HeBIS-PPN:428592406
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0