Strategies to enhance rational use of antibiotics in hospital : a guideline by the German society for infectious diseases

  • Introduction: In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute. Materials and methods: A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development. Conclusion: The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.

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Author:Katja de With, Franz AllerbergerORCiDGND, Steffen Ammann, Petra Apfalter, Hans-Reinhard BrodtGND, Tim Eckmanns, Matthias Fellhauer, Heinrich K. Geiss, Oskar Janata, Robert Krause, Sebastian Lemmen, Elisabeth Meyer, Helmut Mittermayer, Ulla Porsche, Elisabeth Presterl, Stefan Reuter, Bhanu Sinha, Richard Strauß, Agnes Wechsler-Fördös, Christoph Wenisch, Winfried V. Kern
URN:urn:nbn:de:hebis:30:3-430091
URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889644
DOI:https://doi.org/10.1007/s15010-016-0885-z
ISSN:1439-0973
ISSN:0300-8126
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/27066980
Parent Title (English):Infection
Publisher:Urban & Vogel ; Springer
Place of publication:München ; Berlin ; Heidelberg
Contributor(s):Stephan Harbarth, Viktoria Mühlbauer, Sina Helbig
Document Type:Article
Language:English
Date of Publication (online):2017/03/16
Date of first Publication:2016/04/11
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2017/03/16
Tag:ABS; Antibiotic stewardship; Antimicrobial resistance; Guideline; Quality of care; Rational use
Volume:44
Issue:3, Art. 885
Page Number:45
First Page:395
Last Page:439
Note:
© The Author(s) 2016. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
HeBIS-PPN:42778087X
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0