Neurogenic bowel dysfunction in children and adolescents

  • Neurogenic/neuropathic bowel dysfunction (NBD) is common in children who are affected by congenital and acquired neurological disease, and negatively impacts quality of life. In the past, NBD received less attention than neurogenic bladder, generally being considered only in spina bifida (the most common cause of pediatric NBD). Many methods of conservative and medical management of NBD are reported, including relatively recently Transanal Irrigation (TAI). Based on the literature and personal experience, an expert group (pediatric urologists/surgeons/gastroenterologists with specific experience in NBD) focused on NBD in children and adolescents. A statement document was created using a modified Delphi method. The range of causes of pediatric NBD are discussed in this paper. The various therapeutic approaches are presented to improve clinical management. The population of children and adolescents with NBD is increasing, due both to the higher survival rate and better diagnosis. While NBD is relatively predictable in producing either constipation or fecal incontinence, or both, its various effects on each patient will depend on a wide range of underlying causes and accompanying comorbidities. For this reason, management of NBD should be tailored individually with a combined multidisciplinary therapy appropriate for the status of the affected child and caregivers.

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Metadaten
Author:Giovanni Mosiello, Shaista Safder, David Marshall, Udo RolleORCiDGND, Marc A. Benninga
URN:urn:nbn:de:hebis:30:3-621331
DOI:https://doi.org/10.3390/jcm10081669
ISSN:2077-0383
Parent Title (English):Journal of Clinical Medicine
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Date of Publication (online):2021/04/13
Date of first Publication:2021/04/13
Publishing Institution:Universit├Ątsbibliothek Johann Christian Senckenberg
Release Date:2021/10/19
Tag:adolescent; anorectal malformation; bowel dysfunction; cerebral palsy; children; constipation; fecal incontinence; neurogenic bowel; pediatric; spina bifida
Volume:10
Issue:8, art. 1669
Page Number:30
First Page:1
Last Page:30
HeBIS-PPN:488124018
Institutes:Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universit├Ątspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0