Influenza vaccination in psoriatic patients - epidemiology and patient perceptions: a german multicenter study (Vac-Pso)

  • The risk of developing severe complications from an influenza virus infection is increased in patients with chronic inflammatory diseases such as psoriasis (PsO) and atopic dermatitis (AD). However, low influenza vaccination rates have been reported. The aim of this study was to determine vaccination rates in PsO compared to AD patients and explore patient perceptions of vaccination. A multicenter cross-sectional study was performed in 327 and 98 adult patients with PsO and AD, respectively. Data on vaccination, patient and disease characteristics, comorbidity, and patient perceptions was collected with a questionnaire. Medical records and vaccination certificates were reviewed. A total of 49.8% of PsO and 32.7% of AD patients were vaccinated at some point, while in season 2018/2019, 30.9% and 13.3% received an influenza vaccination, respectively. There were 96.6% and 77.6% of PsO and AD patients who had an indication for influenza vaccination due to age, immunosuppressive therapy, comorbidity, occupation, and/or pregnancy. Multivariate regression analysis revealed higher age (p < 0.001) and a history of bronchitis (p = 0.023) as significant predictors of influenza vaccination in PsO patients. Considering that most patients had an indication for influenza vaccination, the rate of vaccinated patients was inadequately low.

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Author:Christian KromerORCiDGND, Phoebe Wellmann, Ralf Siemer, Selina Klein, Johannes MohrGND, Andreas PinterORCiDGND, Dagmar Irmgard Wilsmann-TheisORCiDGND, Rotraut MößnerORCiDGND
URN:urn:nbn:de:hebis:30:3-621922
DOI:https://doi.org/10.3390/vaccines9080843
ISSN:2076-393X
Parent Title (English):Vaccines
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Date of Publication (online):2021/08/01
Date of first Publication:2021/08/01
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2022/07/04
Tag:atopic dermatitis; influenza; pneumonia; psoriasis; vaccination
Volume:9.2021
Issue:8, art. 843
Article Number:843
Page Number:14
First Page:1
Last Page:14
Note:
This research was partially funded by a research grant from Novartis Pharma. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
HeBIS-PPN:502525304
Institutes:Medizin
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 51 Mathematik / 510 Mathematik
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0