The rising burden of spondylodiscitis in Germany: An epidemiologic study based on the federal statistical office database

  • Introduction: Spondylodiscitis is the commonest form of infectious disease of the spine and harbours a high mortality rate of up to 20%. Recent demographic trends in Germany, such as an aging population, immunosuppression, and intravenous drug use, suggest that the incidence of spondylodiscitis may be on the rise. However, the exact epidemiological development of the disease remains uncertain. This study aims to analyse the burden on the tertiary healthcare system in Germany using data from the Federal Statistical Office of Germany (FSOG) database. Materials and Methods: All cases of spondylodiscitis diagnosed between 2005 and 2021 were identified from the FSOG database. The study characterised the mean duration of hospital stays, total and population-adjusted number of diagnoses made, age-stratified incidence, and outcomes of hospitalised patients. Results: A total of 131,982 diagnoses for spondylodiscitis were identified between 2005 and 2021. The number of diagnoses for spondylodiscitis has doubled during this period, from 5.4/100,000 population in 2005 to 11/100,000 population in 2021. The highest increase in admissions was recorded for those aged 90 years and above (+1307%), 80-89 (+376%) and 70-79 (+99%). Hospital discharges to rehabilitation facilities have increased by 160%, and discharges against medical advice by 91%. On the other hand, during the analysed period, the in-hospital mortality rate has decreased by 52%. Conclusion: The population-adjusted incidence of spondylodiscitis in Germany has more than doubled between 2005 and 2021, highlighting the clinical relevance of this disease. During the same period, in-hospital mortality dropped by half. These findings suggest the need for further investigation into optimal therapy, particularly the role and timing of surgical treatment.

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Author:Andreas KramerGND, Santhosh G. ThavarajasingamORCiD, Jonathan Andreas Hans-Günter NeuhoffGND, Benjamin DaviesORCiD, Andreas K. DemetriadesORCiDGND, Ehab ShibanORCiDGND, Florian Alexander RingelORCiDGND
Parent Title (English):Brain and Spine
Place of publication:Amsterdam
Document Type:Conference Proceeding
Date of Publication (online):2023/10/04
Date of first Publication:2023/10/04
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Contributing Corporation:Eurospine (2023 : Frankfurt, Main)
Release Date:2023/10/28
Issue:Supplement 2, 102466
Article Number:102466
Page Number:2
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International