TY  - JOUR
A1  - Grünewald, Leon David
A1  - Booz, Christian
A1  - Martin, Simon S.
A1  - Mahmoudi, Scherwin
A1  - Yel, Ibrahim
A1  - Eichler, Katrin
A1  - Alizadeh, Leona Soraja
A1  - Bernatz, Simon
A1  - Gotta, Jennifer
A1  - Reschke, Philipp
A1  - Weber, Christophe
A1  - Sommer, Christof M.
A1  - D’Angelo, Tommaso
A1  - Bucolo, Giuseppe
A1  - Leistner, David M.
A1  - Vogl, Thomas J.
A1  - Koch, Vitali
T1  - Diagnostic performance of modern computed tomography in cruciate ligament injury detection: a comprehensive study
T2  - European journal of radiology
N2  - Highlights
• Early reconstruction of injured cruciate ligaments improves functional outcomes.
• Modern CT imaging can be used to rapidly identify patients with injury to the cruciate ligaments and streamline therapeutic pathways.
• Dual-energy CT demonstrates superior diagnostic accuracy compared to single-energy CT.

Abstract
Background: This study aimed to evaluate the clinical utility of modern single and dual-energy computed tomography (CT) for assessing the integrity of the cruciate ligaments in patients that sustained acute trauma.
Methods: Patients who underwent single- or dual-energy CT followed by 3 Tesla magnetic resonance imaging (MRI) or knee joint arthroscopy between 01/2016 and 12/2022 were included in this retrospective, monocentric study. Three radiologists specialized in musculoskeletal imaging independently evaluated all CT images for the presence of injury to the cruciate ligaments. An MRI consensus reading of two experienced readers and arthroscopy provided the reference standard. Diagnostic accuracy parameters and area under the receiver operator characteristic curve (AUC) were the primary metrics for diagnostic performance.
Results: CT images of 204 patients (median age, 49 years; IQR 36 – 64; 113 males) were evaluated. Dual-energy CT yielded significantly higher diagnostic accuracy and AUC for the detection of injury to the anterior (94% [240/255] vs 75% [266/357] and 0.89 vs 0.66) and posterior cruciate ligaments (95% [243/255] vs 87% [311/357] and 0.90 vs 0.61) compared to single-energy CT (all parameters, p <.005). Diagnostic confidence and image quality were significantly higher in dual-energy CT compared to single-energy CT (all parameters, p <.005).
Conclusions: Modern dual-energy CT is readily available and can serve as a screening tool for detecting or excluding cruciate ligament injuries in patients with acute trauma. Accurate diagnosis of cruciate ligament injuries is crucial to prevent adverse outcomes, including delayed treatment, chronic instability, or long-term functional limitations.
KW  - Multidetector computed tomography
KW  - Knee joint
KW  - Magnetic resonance Imaging
KW  - Anterior cruciate ligament
KW  - Posterior cruciate ligament
Y1  - 2023
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/82793
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-827930
SN  - 0720-048X
VL  - 170
IS  - 111235
PB  - Elsevier
CY  - Amsterdam
ER  -