TY  - JOUR
A1  - Buechner, Philipp
A1  - Hinderer, Marc
A1  - Unberath, Philipp
A1  - Metzger, Patrick
A1  - Boeker, Martin
A1  - Acker, Till
A1  - Haller, Florian
A1  - Mack, Elisabeth
A1  - Nowak, Daniel
A1  - Paret, Claudia
A1  - Schanze, Denny
A1  - Bubnoff, Nikolas von
A1  - Wagner, Sebastian Alexander
A1  - Busch, Hauke
A1  - Börries, Melanie
A1  - Christoph, Jan
T1  - Requirements analysis and specification for a molecular tumor board platform based on cBioPortal
T2  - Diagnostics
N2  - Clinicians in molecular tumor boards (MTB) are confronted with a growing amount of genetic high-throughput sequencing data. Today, at German university hospitals, these data are usually handled in complex spreadsheets from which clinicians have to obtain the necessary information. The aim of this work was to gather a comprehensive list of requirements to be met by cBioPortal to support processes in MTBs according to clinical needs. Therefore, oncology experts at nine German university hospitals were surveyed in two rounds of interviews. To generate an interview guideline a scoping review was conducted. For visual support in the second round, screenshot mockups illustrating the requirements from the first round were created. Requirements that cBioPortal already meets were skipped during the second round. In the end, 24 requirements with sometimes several conceivable options were identified and 54 screenshot mockups were created. Some of the identified requirements have already been suggested to the community by other users or are currently being implemented in cBioPortal. This shows, that the results are in line with the needs expressed by various disciplines. According to our findings, cBioPortal has the potential to significantly improve the processes and analyses of an MTB after the implementation of the identified requirements.
KW  - decision making
KW  - computer-assisted
KW  - decision support systems
KW  - clinical
KW  - precision medicine
KW  - computational biology
KW  - molecular tumor board
KW  - cBioPortal
KW  - requirements analysis
KW  - neoplasms
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/54420
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-544207
VL  - 10
IS  - 93
PB  - MDPI
CY  - Basel
ER  -