TY  - JOUR
A1  - Magenta, Alessandra
A1  - Greco, Simona
A1  - Capogrossi, Maurizio C.
A1  - Gaetano, Carlo
A1  - Martelli, Fabio
T1  - Nitric oxide, oxidative stress, and p66Shc interplay in diabetic endothelial dysfunction
T2  - BioMed research international
N2  - Increased oxidative stress and reduced nitric oxide (NO) bioavailability play a causal role in endothelial cell dysfunction occurring in the vasculature of diabetic patients. In this review, we summarized the molecular mechanisms underpinning diabetic endothelial and vascular dysfunction. In particular, we focused our attention on the complex interplay existing among NO, reactive oxygen species (ROS), and one crucial regulator of intracellular ROS production, p66Shc protein.
Y1  - 2014
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/33470
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-334705
SN  - 2314-6133
SN  - 2314-6141
N1  - Copyright © 2014 Alessandra Magenta et al. This is an open access article distributed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 2014
IS  - Article ID 193095
PB  - Hindawi
CY  - New York, NY [u.a.]
ER  -