TY  - JOUR
A1  - Taumberger, Nadja
A1  - Schütz, Anna-Maria
A1  - Jeitler, Klaus
A1  - Siebenhofer, Andrea
A1  - Simonis, Holger
A1  - Bornemann-Cimenti, Helmar
A1  - Laky, Rene
A1  - Tamussino, Karl
T1  - Preemptive local analgesia at vaginal hysterectomy: a systematic review
T2  - International Urogynecology Journal
N2  - Introduction and hypothesis: We conducted a systematic review of the effectiveness of local preemptive analgesia for postoperative pain control in women undergoing vaginal hysterectomy.
Methods: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews were searched systematically to identify eligible studies published through September 25, 2019. Only randomized controlled trials and systematic reviews addressing local preemptive analgesia compared to placebo at vaginal hysterectomy were considered. Data were extracted by two independent reviewers. Results were compared, and disagreement was resolved by discussion. Forty-seven studies met inclusion criteria for full-text review. Four RCTs, including a total of 197 patients, and two SRs were included in the review.
Results: Preemptive local analgesia reduced postoperative pain scores up to 6 h and postoperative opioid requirements in the first 24 h after surgery.
Conclusion: Preemptive local analgesia at vaginal hysterectomy results in less postoperative pain and less postoperative opioid consumption.
KW  - postoperative pain
KW  - local preemptive analgesia
KW  - vaginal hysterectomy
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/75448
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-754481
SN  - 1433-3023
VL  - 33
IS  - 9
SP  - 2357
EP  - 2366
PB  - Springer
CY  - London [u.a]
ER  -