TY  - JOUR
A1  - Thalor, Sunil Kumar
A1  - Berberich, Thomas
A1  - Lee, Sung Shin
A1  - Yang, Seung Hwan
A1  - Zhu, XuJun
A1  - Imai, Ryozo
A1  - Takahashi, Yoshihiro
A1  - Kusano, Tomonobu
T1  - Deregulation of sucrose-controlled translation of a bZIP-type transcription factor results in sucrose accumulation in leaves
T2  - PLoS One
N2  - Sucrose is known to repress the translation of Arabidopsis thaliana AtbZIP11 transcript which encodes a protein belonging to the group of S (S - stands for small) basic region-leucine zipper (bZIP)-type transcription factor. This repression is called sucrose-induced repression of translation (SIRT). It is mediated through the sucrose-controlled upstream open reading frame (SC-uORF) found in the AtbZIP11 transcript. The SIRT is reported for 4 other genes belonging to the group of S bZIP in Arabidopsis. Tobacco tbz17 is phylogenetically closely related to AtbZIP11 and carries a putative SC-uORF in its 5′-leader region. Here we demonstrate that tbz17 exhibits SIRT mediated by its SC-uORF in a manner similar to genes belonging to the S bZIP group of the Arabidopsis genus. Furthermore, constitutive transgenic expression of tbz17 lacking its 5′-leader region containing the SC-uORF leads to production of tobacco plants with thicker leaves composed of enlarged cells with 3–4 times higher sucrose content compared to wild type plants. Our finding provides a novel strategy to generate plants with high sucrose content.
Y1  - 2012
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/24385
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-243854
SN  - 1932-6203
VL  - 7
IS  - 3: e33111
PB  - Public Library of Science
CY  - Lawrence, Kan.
ER  -