TY  - JOUR
A1  - Bretzke, Maria
A1  - Wahl, Hannes
A1  - Plichta, Michael M.
A1  - Wolff, Nicole
A1  - Rößner, Veit
A1  - Vetter, Nora
A1  - Buse, Judith
T1  - Ventral striatal activation during reward anticipation of different reward probabilities in adolescents and adults
T2  - Frontiers in human neuroscience
N2  - Adolescence has been linked to an enhanced tolerance of uncertainty and risky behavior and is possibly connected to an increased response toward rewards. However, previous research has produced inconsistent findings. To investigate whether these findings are due to different reward probabilities used in the experimental design, we extended a monetary incentive delay (MID) task by including three different reward probabilities. Using functional magnetic resonance imaging, 25 healthy adolescents and 22 adults were studied during anticipation of rewards in the VS. Differently colored cue stimuli indicated either a monetary or verbal trial and symbolized different reward probabilities, to which the participants were blinded. Results demonstrated faster reaction times for lower reward probabilities (33%) in both age groups. Adolescents were slower through all conditions and had less activation on a neural level. Imaging results showed a three-way interaction between age group x condition x reward probability with differences in percent signal change between adolescents and adults for the high reward probabilities (66%, 88%) while adolescents demonstrated differences for the lowest (33%). Therefore, previous inconsistent findings could be due to different reward probabilities, which makes examining these crucial for a better understanding of adolescent and adult behavior.
KW  - adolescence
KW  - development
KW  - fMRI
KW  - reward probabilities
KW  - reward
KW  - ventral striatum
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/62012
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-620121
SN  - 1662-5161
N1  - NV was funded by Deutsche Forschungsgemeinschaft, Grant/Award Numbers: VE 892/2-1. NW received funding from the Else-Kröner-Fresenius- Stiftung 2017_A101. The authors acknowledge support by the Open Access Publication Funds of the TU Dresden.
VL  - 15
IS  - art. 649724
SP  - 1
EP  - 13
PB  - Frontiers Reserch Foundation
CY  - Lausanne
ER  -