TY  - JOUR
A1  - Depprich, Rita
A1  - Zipprich, Holger
A1  - Ommerborn, Michelle
A1  - Naujoks, Christian
A1  - Wiesmann, Hans-Peter
A1  - Kiattavorncharoen, Sirichai
A1  - Lauer, Hans-Christoph
A1  - Meyer, Ulrich
A1  - Kübler, Norbert
A1  - Handschel, Jörg
T1  - Osseointegration of zirconia implants compared with titanium : an in vivo study
T2  - Head & face medicine
N2  - Background Titanium and titanium alloys are widely used for fabrication of dental implants. Since the material composition and the surface topography of a biomaterial play a fundamental role in osseointegration, various chemical and physical surface modifications have been developed to improve osseous healing. Zirconia-based implants were introduced into dental implantology as an altenative to titanium implants. Zirconia seems to be a suitable implant material because of its tooth-like colour, its mechanical properties and its biocompatibility. As the osseointegration of zirconia implants has not been extensively investigated, the aim of this study was to compare the osseous healing of zirconia implants with titanium implants which have a roughened surface but otherwise similar implant geometries. Methods Forty-eight zirconia and titanium implants were introduced into the tibia of 12 minipigs. After 1, 4 or 12 weeks, animals were sacrificed and specimens containing the implants were examined in terms of histological and ultrastructural techniques. Results Histological results showed direct bone contact on the zirconia and titanium surfaces. Bone implant contact as measured by histomorphometry was slightly better on titanium than on zirconia surfaces. However, a statistically significant difference between the two groups was not observed. Conclusion The results demonstrated that zirconia implants with modified surfaces result in an osseointegration which is comparable with that of titanium implants.
Y1  - 2008
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/6527
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30-65972
SN  - 1746-160X
N1  - © 2008 Depprich et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 4
IS  - 30
SP  - 1
EP  - 8
PB  - BioMed Central
CY  - London
ER  -