TY  - JOUR
A1  - Spjut, Richard W.
A1  - Kingston, David G. I.
A1  - Cassady, John M.
T1  - Systematic screening of bryophytes for antitumor agents
T2  - Tropical bryology
N2  - References are made to cytotoxic and/or antitumor compounds that have been isolated - ansamitocin P-3 from Claopodium crispifolium (Hook.) Ren. & Card. and Anomodon attenuatus Hueb., or an associated actinomycete, and ohioensins and pallidisetums from Polytrichum spp. Several hundred collections, which have been obtained from temperate regions of North America during 1990 and 1991, are currently being screened in new bioassays; active sesquiterpene lactones have been recently isolated from species of Porella. The methodologies of collecting and screening bryophyte samples are discussed with consideration to costs based on expected number of samples that might be collected in a day, the diversity in the collections as related to phytogeography and vegetation types, and the bryophyte cover that is vanishing in many forest regions of the United States. The difficulties in obtaining large collections for isolation of active agents are also discussed by examplerecollection of Claopodium crispifolium.
Y1  - 1992
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/30231
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-302312
SN  - 0935-5626
N1  - The layout of the electronic version of this contribution differs from the layout of the original version published in the printed volume.
IS  - 6
SP  - 193
EP  - 202
PB  - D. Quandt, Univ. Bonn, Nees Inst. für Biodiversität d. Pflanzen
CY  - Bonn
ER  -