TY  - JOUR
A1  - Freyschlag, Christian Franz
A1  - Krieg, Sandro
A1  - Kerschbaumer, Johannes
A1  - Pinggera, Daniel
A1  - Forster, Marie-Thérèse
A1  - Cordier, Dominik
A1  - Rossi, Marco
A1  - Miceli, Gabriele
A1  - Roux, Alexandre
A1  - Reyes, Andrés
A1  - Sarubbo, Silvio
A1  - Smits, Anja
A1  - Sierpowska, Joanna
A1  - Robe, Pierre A.
A1  - Rutten, Geert‑Jan
A1  - Santarius, Thomas
A1  - Matys, Tomasz
A1  - Zanello, Marc
A1  - Almairac, Fabien
A1  - Mondot, Lydiane
A1  - Jakola, Asgeir Store
A1  - Zetterling, Maria
A1  - Rofes, Adrià
A1  - Campe, Gord von
A1  - Guillevin, Remy
A1  - Bagatto, Daniele
A1  - Lubrano, Vincent
A1  - Rapp, Marion
A1  - Goodden, John
A1  - Witt Hamer, Philip C. de
A1  - Pallud, Johan
A1  - Bello, Lorenzo
A1  - Thomé, Claudius
A1  - Duffau, Hugues
A1  - Mandonnet, Emmanuel
T1  - Imaging practice in low-grade gliomas among European specialized centers and proposal for a minimum core of imaging
T2  - Journal of neuro-oncology
N2  - Objective: Imaging studies in diffuse low-grade gliomas (DLGG) vary across centers. In order to establish a minimal core of imaging necessary for further investigations and clinical trials in the field of DLGG, we aimed to establish the status quo within specialized European centers.
Methods: An online survey composed of 46 items was sent out to members of the European Low-Grade Glioma Network, the European Association of Neurosurgical Societies, the German Society of Neurosurgery and the Austrian Society of Neurosurgery.
Results: A total of 128 fully completed surveys were received and analyzed. Most centers (n = 96, 75%) were academic and half of the centers (n = 64, 50%) adhered to a dedicated treatment program for DLGG. There were national differences regarding the sequences enclosed in MRI imaging and use of PET, however most included T1 (without and with contrast, 100%), T2 (100%) and TIRM or FLAIR (20, 98%). DWI is performed by 80% of centers and 61% of centers regularly performed PWI.
Conclusion: A minimal core of imaging composed of T1 (w/wo contrast), T2, TIRM/FLAIR, PWI and DWI could be identified. All morphologic images should be obtained in a slice thickness of ≤ 3 mm. No common standard could be obtained regarding advanced MRI protocols and PET.
Importance of the study: We believe that our study makes a significant contribution to the literature because we were able to determine similarities in numerous aspects of LGG imaging. Using the proposed "minimal core of imaging" in clinical routine will facilitate future cooperative studies.
KW  - Low-grade glioma
KW  - Imaging in LGG
KW  - Minimal core of imaging
KW  - Response criteria
Y1  - 2018
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/50799
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-507998
SN  - 1573-7373
SN  - 0167-594x
N1  - Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
VL  - 139
IS  - 3
SP  - 699
EP  - 711
PB  - Springer Science + Business Media B.V
CY  - Dordrecht [u. a.]
ER  -