TY  - JOUR
A1  - Polito, Maria Vincenza
A1  - Stöbe, Stephan
A1  - Galasso, Gennaro
A1  - De Rosa, Roberta
A1  - Citro, Rodolfo
A1  - Piscione, Federico
A1  - Laufs, Ulrich
A1  - Hagendorff, Andreas
T1  - Analysis of regional right ventricular function by tissue doppler imaging in patients with aortic stenosis
T2  - Journal of Cardiovascular Echography
N2  - Background: Right ventricular (RV) dysfunction is frequently observed in patients with aortic stenosis (AS). Nevertheless, assessment of regional RV deformation is yet not performed. The aim of the study was to analyze the impact of moderate and severe AS on global and regional RV function by a multisegmental approach using tissue Doppler imaging (TDI).
Methods: In 50 patients (Group I – AS [n = 25] and Group II – normal controls [n = 25]), additional echocardiographic views of the RV were prospectively performed. The TDI sample volume was placed in the basal myocardial region of the anterior (RV-anterior), inferior (RV-inferior), and free RV wall (RV-free wall) to assess the following parameters: S'RV, E'RV, and A'RV waves; IVCTRV; IVRTRV; and myocardial performance index (MPIRV).
esults: In AS patients, left ventricular (LV) mass index, left atrial (LA) volume index, and LV end-diastolic pressure were significantly increased. Moreover, AS patients had higher systolic pulmonary artery pressure (sPAP) and lower values for PV AccT (P < 0.0001), but TAPSE was not different between the two groups (P = 0.062). In AS patients, IVRTRV-anterior, IVRTRV-inferior, and IVRTRV-freewall and MPIRV were statistically increased (P < 0.0001). A significant correlation between IVRTRV (evaluated at all three regions) and the parameters including sPAP, PV AccT, and ELV/e'LV ratio was observed in AS. A strong correlation was observed between IVRTRV-freewall/inferior and AS severity by evaluation of velocities, gradient, and aortic valve area (P < 0.0001).
Conclusions: The present study reports a correlation between the severity of AS and the increase of IVRTRV and MPIRV. Thus, a distinct analysis of RV performance is important for echocardiographic evaluation of patients with AS.
KW  - Aortic stenosis
KW  - echocardiography
KW  - right ventricular function
KW  - tissue Doppler imaging
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/53348
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-533487
SN  - 2347-193X
SN  - 2211-4122
N1  - CC BY-NC-SA http://creativecommons.org/licenses/by-nc-sa/4.0/
VL  - 29
IS  - 3
SP  - 111
EP  - 118
PB  - Medknow
CY  - Mumbai
ER  -