TY - JOUR A1 - Kiyose, Makoto A1 - Wagner, Marlies A1 - Männer, Annika A1 - Reitz, Sarah A1 - Klein, Karl Martin A1 - Strzelczyk, Adam A1 - Bauer, Sebastian A1 - Rosenow, Felix T1 - Long term seizure freedom on perampanel in highly drug-resistant epilepsy caused by bilateral periventricular nodular heterotopia: a case report T2 - Epilepsy & behavior case reports N2 - Highlights • NMDA-receptor subunit expression of NR2A and NR2B is downregulated in heterotopias. • Glutamatergic transmission in the hyperexcitability of nodular heterotopias is implicated. • Mechanisms in PVNH to establish etiology specific therapies are still to be defined. Y1 - 2019 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/77500 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-775004 SN - 2213-3232 VL - 11 SP - 99 EP - 102 PB - Elsevier CY - Amsterdam ER -