TY  - JOUR
A1  - Dávidová, Petra
A1  - Müller, Michael
A1  - Wenner, Yaroslava
A1  - König, Clara
A1  - Kenikstul, Ninel
A1  - Kohnen, Thomas
T1  - Ophthalmic artery occlusion after glabellar hyaluronic acid filler injection
T2  - American journal of ophthalmology. Case reports
N2  - Purpose: Filler injections for aesthetic purposes are very popular, but can have far-reaching and irreversible consequences. This report describes the course of a patient with devastating complications after glabellar hyaluronic acid injection, their pathomechanism, management and outcome.
Observations: A healthy, 43-year-old woman underwent her first hyaluronic acid injection in the glabella and went blind on her left eye immediately thereafter. Massaging of the injection area and observation were performed, before she presented with swelling of the left forehead and upper lid, ptosis, complete ophthalmoplegia and blindness in our hospital. Immediate massaging of the globe and systemic therapy including acetylsalicylic acid, tinzaparin sodium and cortisone was initiated and hyaluronidase injections in the injection area were performed. In the further course, the patient developed necrotic and hemorrhagic skin and mucosal lesions, lagophthalmos, anterior and posterior segment ischemia and globe hypotonia with consecutive globe deformation. In the follow-up of 2.5 months, lid swelling, lagophthalmos and ptosis resolved and keratopathy improved but blindness, skin lesions and strabismus with reduced eye motility were still present and madarosis and early enophthalmos were detected.
Conclusions and Importance: The outcome of ophthalmic artery occlusion after hyaluronic acid filler injection is poor. Sufficient knowledge about facial anatomy, the implementation of filler injections and the management of complications is essential for the practitioner. The patient should be clarified about potential and even rare risks of these procedures.
KW  - Filler
KW  - Glabella
KW  - Blindness
KW  - Ophthalmoplegia
KW  - Arteria ophthalmica
KW  - Occlusion
Y1  - 2022
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/78297
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-782973
SN  - 2451-9936
VL  - 26
IS  - 101407
PB  - Elsevier
CY  - Amsterdam
ER  -