TY  - INPR
A1  - Falck, Johannes
A1  - Zhang, Lei
A1  - Raffington, Laurel
A1  - Mohn, Johannes Julius
A1  - Triesch, Jochen
A1  - Heim, Christine
A1  - Shing, Yee Lee
T1  - Longitudinal changes in value-based learning in middle childhood: distinct contributions of hippocampus and striatum
T2  - bioRxiv
N2  - The hippocampal-dependent memory system and striatal-dependent memory system modulate reinforcement learning depending on feedback timing in adults, but their contributions during development remain unclear. In a 2-year longitudinal study, 6-to-7-year-old children performed a reinforcement learning task in which they received feedback immediately or with a short delay following their response. Children’s learning was found to be sensitive to feedback timing modulations in their reaction time and inverse temperature parameter, which quantifies value-guided decision-making. They showed longitudinal improvements towards more optimal value-based learning, and their hippocampal volume showed protracted maturation. Better delayed model-derived learning covaried with larger hippocampal volume longitudinally, in line with the adult literature. In contrast, a larger striatal volume in children was associated with both better immediate and delayed model-derived learning longitudinally. These findings show, for the first time, an early hippocampal contribution to the dynamic development of reinforcement learning in middle childhood, with neurally less differentiated and more cooperative memory systems than in adults.
Y1  - 2023
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/83073
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-830736
UR  - https://www.biorxiv.org/content/10.1101/2023.04.13.536699v2
IS  - 2023.04.13.536699 Version 2
PB  - bioRxiv
ER  -