TY - INPR A1 - Wells, Carrow I. A1 - Al-Ali, Hassan A1 - Andrews, David M. A1 - Asquith, Christopher R. M. A1 - Axtman, Alison D. A1 - Chung, Mirra A1 - Đikić, Ivan A1 - Ebner, Daniel A1 - Elkins, Jonathan M. A1 - Ettmayer, Peter A1 - Fischer, Christian A1 - Frederiksen, Mathias A1 - Gray, Nathanael S. A1 - Hatch, Stephanie A1 - Knapp, Stefan A1 - Lee, Shudong A1 - Lücking, Ulrich A1 - Michaelides, Michael A1 - Mills, Caitlin E. A1 - Müller, Susanne A1 - Owen, Dafydd R. A1 - Picado, Alfredo A1 - Ramadan, Kristijan A1 - Saikatendu, Kumar S. A1 - Schröder, Martin A1 - Stolz, Alexandra A1 - Tellechea, Mariana A1 - Treiber, Daniel K. A1 - Turunen, Brandon J. A1 - Vilar, Santiago A1 - Wang, Jinhua A1 - Zuercher, William J. A1 - Willson, Timothy M. A1 - Drewry, David H. T1 - The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification T2 - bioRxiv N2 - We describe the assembly and annotation of a chemogenomic set of protein kinase inhibitors as an open science resource for studying kinase biology. The set only includes inhibitors that show potent kinase inhibition and a narrow spectrum of activity when screened across a large panel of kinase biochemical assays. Currently, the set contains 187 inhibitors that cover 215 human kinases. The kinase chemogenomic set (KCGS) is the most highly annotated set of selective kinase inhibitors available to researchers for use in cell-based screens. Y1 - 2019 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/72679 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-726793 UR - https://www.biorxiv.org/content/10.1101/2019.12.22.886523v1 IS - 2019.12.22.886523 Version 1 PB - bioRxiv ER -