TY - JOUR A1 - Kashefiolasl, Sepide A1 - Brawanski, Nina A1 - Platz, Johannes A1 - Bruder, Markus A1 - Senft, Christian A1 - Marquardt, Gerhard A1 - Seifert, Volker A1 - Tritt, Stephanie A1 - Konczalla, Jürgen T1 - MRI-detection rate and incidence of lumbar bleeding sources in 190 patients with non-aneurysmal SAH T2 - PLoS one N2 - Background: Up to 15% of all spontaneous subarachnoid hemorrhages (SAH) have a non-aneurysmal SAH (NASAH). The evaluation of SAH patients with negative digital subtraction angiography (DSA) is sometimes a diagnostic challenge. Our goal in this study was to reassess the yield of standard MR-imaging of the complete spinal axis to rule out spinal bleeding sources in patients with NASAH. Methods: We retrospectively analyzed the spinal MRI findings in 190 patients with spontaneous NASAH, containing perimesencephalic (PM) and non-perimesencephalic (NPM) SAH, diagnosed by computer tomography (CT) and/or lumbar puncture (LP), and negative 2nd DSA. Results: 190 NASAH patients were included in the study, divided into PM-SAH (n = 87; 46%) and NPM-SAH (n = 103; 54%). Overall, 23 (22%) patients had a CT negative SAH, diagnosed by positive LP. MR-imaging of the spinal axis detected two patients with lumbar ependymoma (n = 2; 1,05%). Both patients complained of radicular sciatic pain. The detection rate raised up to 25%, if only patients with radicular sciatic pain received an MRI. Conclusion: Routine radiological investigation of the complete spinal axis in NASAH patients is expensive and can not be recommended for standard procedure. However, patients with clinical signs of low-back/sciatic pain should be worked up for a spinal pathology. Y1 - 2017 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43249 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-432499 SN - 1932-6203 N1 - Copyright: © 2017 Kashefiolasl et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. VL - 12 IS - (4): e0174734 SP - 1 EP - 11 PB - PLoS CY - Lawrence, Kan. ER -