TY  - JOUR
A1  - Reimann, Carolin
A1  - Puentes, Margarita
A1  - Maasch, Matthias
A1  - Hübner, Frank
A1  - Bazrafshan, Babak
A1  - Vogl, Thomas J.
A1  - Damm, Christian
A1  - Jakoby, Rolf
T1  - Planar microwave sensor for theranostic therapy of organic tissue based on oval split ring resonators
T2  - Sensors
N2  - Microwave sensors in medical environments play a significant role due to the contact-less and non-invasive sensing mechanism to determine dielectric properties of tissue. In this work, a theranostic sensor based on Split Ring Resonators (SRRs) is presented that provides two operation modes to detect and treat tumor cells, exemplary in the liver. For the detection mode, resonance frequency changes due to abnormalities are evaluated, and in the treatment mode, microwave ablation is performed. The planar sensor structure can be integrated into a needle like a surgery tool that evokes challenges concerning size limitations and biocompatibility. To meet the size requirements and provide a reasonable operating frequency, properties of oval shaped SRRs are investigated. By elongating the radius of the SRR in one direction, the resonance frequency can be decreased significantly compared to circular SRR by a factor of two below 12 GHz. In order to validate the detection and treatment characteristics of the sensor, full wave simulations and measurements are examined. Clear resonance shifts are detected for loading the sensor structures with phantoms mimicking healthy and malignant tissue. For treatment mode evaluation, ex vivo beef liver tissue was ablated leading to a lesion zone 1.2 cm × 1 cm × 0.3 cm with a three minute exposure of maximum 2.1 W
KW  - theranostics
KW  - oval split ring resonator
KW  - microwave ablation
Y1  - 2016
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/53267
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-532676
SN  - 1424-8220
N1  - This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 16
IS  - 1450
PB  - MDPI
CY  - Basel
ER  -