TY  - JOUR
A1  - Reitter, Anke
A1  - Stücker, Anja-Undine
A1  - Buxmann, Horst
A1  - Herrmann, Eva
A1  - Haberl, Annette Elisabeth
A1  - Schlößer, Rolf Lambert
A1  - Louwen, Frank
T1  - Prenatal ultrasound screening for fetal anomalies and outcomes in high-risk pregnancies due to maternal HIV infection : a retrospective study
T2  - Infectious diseases in obstetrics and gynecology
N2  - Objective: To assess the prevalence of prenatal screening and of adverse outcome in high-risk pregnancies due to maternal HIV infection. 
Study design: The prevalence of prenatal screening in 330 pregnancies of HIV-positive women attending the department for prenatal screening and/or during labour between January 1, 2002 and December 31, 2012, was recorded. Screening results were compared with the postnatal outcome and maternal morbidity, and mother-to-child transmission (MTCT) was evaluated. 
Results: One hundred of 330 women (30.5%) had an early anomaly scan, 252 (74.5%) had a detailed scan at 20–22 weeks, 18 (5.5%) had a detailed scan prior to birth, and three (0.9%) had an amniocentesis. In seven cases (2.12%), a fetal anomaly was detected prenatally and confirmed postnatally, while in eight (2.42%) an anomaly was only detected postnatally, even though a prenatal scan was performed. There were no anomalies in the unscreened group. MTCT occurred in three cases (0.9%) and seven fetal and neonatal deaths (2.1%) were reported.
Conclusion: The overall prevalence of prenatal ultrasound screening in our cohort is 74.5%, but often the opportunity for prenatal ultrasonography in the first trimester is missed. In general, the aim should be to offer prenatal ultrasonography in the first trimester in all pregnancies. This allows early reassurance or if fetal disease is suspected, further steps can be taken.
Y1  - 2013
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/32274
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-322747
SN  - 1098-0997
SN  - 1064-7449
N1  - Copyright © 2013 A. Reitter et al. This is an open access article distributed under the Creative Commons Attribution License  http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 2013
IS  - Article ID 208482
SP  - 1
EP  - 10
PB  - Hindawi Publishing Corp.
CY  - New York, NY [u.a.]
ER  -