TY - JOUR A1 - Krebs, Mischa A1 - Schmenger, Kai A1 - Neumann, Konrad A1 - Weigl, Paul A1 - Moser, Walter A1 - Nentwig, Georg-Hubertus T1 - Long-term evaluation of ANKYLOS dental implants : 1. 20-year life table analysis of a longitudinal study of more than 12,500 implants T2 - Clinical implant dentistry and related research N2 - Purpose: Scientific evidence is limited regarding the long-term (>10 years) outcomes of large enough numbers of implants (>500) to allow for reliable comparison of subgroups. The purpose of this study was to analyze the outcomes of dental implants placed in an active University Clinic setting and followed for up to 20 years. Materials and Methods: Data documenting the implant placement, prosthetic reconstruction, and annual follow-up of patients treated at Frankfurt University were extracted from a Structured Query Language database and patients’ written records and evaluated statistically. Results: Between April of 1991 and May of 2011, 12,737 ANKYLOS® (DENTSPLY Implants Manufacturing GmbH, Mannheim, Germany) implants were placed in 4,206 patients for a variety of clinical indications. The Kaplan–Meier cumulative survival rate (CSR) was 93.3% after 204 months. Most of the failures (198/1.6%) occurred during the first year after implant placement and before prosthesis delivery. A significantly higher (p < .001) number of implants placed in the mandible and in hard quality bone failed than those placed in the maxilla or in weak and normal quality bone. Female patients had significantly higher CSRs (93.7% 204 months) than male patients (92.8% 204 months/p = .029). The implants showed low rates of peri-implant bone loss after 204 months (horizontal: 21 mm: 85.7%, vertical: 21 mm: 85.2%). Conclusion: ANKYLOS dental implants followed for up to 20 years have high CSRs and low rates of peri-implant bone loss. KW - clinical research KW - clinical study KW - crestal bone loss KW - implant KW - implant survival KW - long-term survival KW - marginal bone loss KW - survival rate Y1 - 2013 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/31648 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-316483 SN - 1708-8208 SN - 1523-0899 N1 - © 2013 The Authors. Clinical Implant Dentistry and Related Research published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/3.0/, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. VL - 2013 IS - S1 SP - 275 EP - 286 PB - Wiley-Blackwell CY - Oxford [u.a.] ER -