TY  - JOUR
A1  - Wicke, Felix Sebastin
A1  - Güthlin, Corina
A1  - Mergenthal, Karola
A1  - Gensichen, Jochen
A1  - Löffler, Christin
A1  - Bickel, Horst
A1  - Maier, Wolfgang
A1  - Riedel-Heller, Steffi Gerlinde
A1  - Weyerer, Siegfried
A1  - Wiese, Birgitt
A1  - König, Hans-Helmut
A1  - Schön, Gerhard
A1  - Hansen, Heike
A1  - Bussche, Hendrik van den
A1  - Scherer, Martin
A1  - Dahlhaus, Anne Maren
T1  - Depressive mood mediates the influence of social support on health-related quality of life in elderly, multimorbid patients
T2  - BMC family practice
N2  - Background: It is not well established how psychosocial factors like social support and depression affect health-related quality of life in multimorbid and elderly patients. We investigated whether depressive mood mediates the influence of social support on health-related quality of life.
Methods: Cross-sectional data of 3,189 multimorbid patients from the baseline assessment of the German MultiCare cohort study were used. Mediation was tested using the approach described by Baron and Kenny based on multiple linear regression, and controlling for socioeconomic variables and burden of multimorbidity.
Results: Mediation analyses confirmed that depressive mood mediates the influence of social support on health-related quality of life (Sobel's p < 0.001). Multiple linear regression showed that the influence of depressive mood (beta = -0.341, p < 0.01) on health-related quality of life is greater than the influence of multimorbidity (beta = -0.234, p < 0.01).
Conclusion: Social support influences health-related quality of life, but this association is strongly mediated by depressive mood. Depression should be taken into consideration in research on multimorbidity, and clinicians should be aware of its importance when caring for multimorbid patients.
KW  - Multimorbidity
KW  - Chronic medical conditions
KW  - Coping
KW  - Primary care
KW  - Family practice
KW  - Social support
KW  - Health-related quality of life
KW  - Depression
KW  - Elderly patients
Y1  - 2014
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/33398
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-333989
SN  - 1471-2296
N1  - © 2014 Wicke et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
VL  - 15
IS  - 62
PB  - BioMed Central
CY  - London
ER  -