TY - JOUR A1 - Abdel Tawab, Mona A1 - Schmitz, Mario A1 - Kamlot, Stefan A1 - Schubert-Zsilavecz, Manfred T1 - Dosing accuracy of two disposable insulin pens according to new ISO 11608-1: 2012 requirements. T2 - Journal of diabetes science and technology N2 - OBJECTIVE: The aim was to compare 2 disposable insulin pens, FlexTouch® (Novo Nordisk, insulin aspart) and SoloSTAR® (Sanofi, insulin glulisine), according to new ISO 11608-1:2012 requirements for dosing accuracy. METHODS: Sixty pens of each type were tested at 1, 40, and 80 U doses. Following the new ISO requirements, each dose was delivered from the front, middle, and rear one-third of the pen. Statistical analysis was performed using Student's t test. RESULTS: Both pens delivered all doses within ISO limits. The difference between the average measured dose and the target dose was significantly smaller for SoloSTAR than FlexTouch at 40 U (P = .009) and 80 U (P = .008), but not at 1 U (P = .417). CONCLUSION: Both insulin pens fulfilled the dosing accuracy requirements defined by ISO 11608-1:2012 at all 3 dosage levels. KW - disposable insulin pens KW - dosing accuracy KW - FlexTouch KW - SoloSTAR Y1 - 2015 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/39563 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-395633 VL - 10 IS - 1 SP - 157 EP - 161 PB - Sage CY - Thousand Oaks, Calif. ER -