TY - JOUR A1 - Boeckel, Jes-Niels A1 - Oppermann, Jana A1 - Anadol, Remzi A1 - Fichtlscherer, Stephan A1 - Zeiher, Andreas M. A1 - Keller, Till T1 - Analyzing the release of copeptin from the heart in acute myocardial infarction using a transcoronary gradient model T2 - Scientific Reports N2 - Copeptin is the C-terminal end of pre-provasopressin released equimolar to vasopressin into circulation and recently discussed as promising cardiovascular biomarker amendatory to established markers such as troponins. Vasopressin is a cytokine synthesized in the hypothalamus. A direct release of copeptin from the heart into the circulation is implied by data from a rat model showing a cardiac origin in hearts put under cardiovascular wall stress. Therefore, evaluation of a potential release of copeptin from the human heart in acute myocardial infarction (AMI) has been done. Y1 - 2016 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/42525 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-425253 N1 - This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ VL - 6 IS - 20812 SP - 1 EP - 5 ER -