TY - JOUR A1 - Meybohm, Patrick A1 - Richards, Toby A1 - Isbister, James A1 - Hofmann, Axel A1 - Shander, Aryeh A1 - Goodnough, Lawrence Tim A1 - Muñoz, Manuel A1 - Gombotz, Hans A1 - Weber, Christian Friedrich A1 - Choorapoikayil, Suma A1 - Spahn, Donat Rudolf A1 - Zacharowski, Kai T1 - Patient blood management bundles to facilitate implementation T2 - Transfusion medicine reviews N2 - More than 30% of the world's population are anemic with serious economic consequences including reduced work capacity and other obstacles to national welfare and development. Red blood cell transfusion is the mainstay to correct anemia, but it is also 1 of the top 5 overused procedures. Patient blood management (PBM) is a proactive, patient-centered, and multidisciplinary approach to manage anemia, optimize hemostasis, minimize iatrogenic blood loss, and harness tolerance to anemia. Although the World Health Organization has endorsed PBM in 2010, many hospitals still seek guidance with the implementation of PBM in clinical routine. Given the use of proven change management principles, we propose simple, cost-effective measures enabling any hospital to reduce both anemia and red blood cell transfusions in surgical and medical patients. This article provides comprehensive bundles of PBM components encompassing 107 different PBM measures, divided into 6 bundle blocks acting as a working template to develop institutions' individual PBM practices for hospitals beginning a program or trying to improve an already existing program. A stepwise selection of the most feasible measures will facilitate the implementation of PBM. In this manner, PBM represents a new quality and safety standard. KW - Anemia KW - Blood loss KW - Blood transfusion KW - Hemostasis KW - Patient blood management Y1 - 2016 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/45891 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-458916 SN - 1532-9496 SN - 0887-7963 N1 - © 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). VL - 31 IS - 1 SP - 62 EP - 71 PB - Elsevier CY - Amsterdam [u. a.] ER -