TY  - JOUR
A1  - Golan, Tal
A1  - Davidesco, Ido
A1  - Meshulam, Meir
A1  - Groppe, David M.
A1  - Mégevand, Pierre
A1  - Yeagle, Erin M.
A1  - Goldfinger, Matthew S.
A1  - Harel, Michal
A1  - Melloni, Lucia
A1  - Schroeder, Charles E.
A1  - Deouell, Leon Y.
A1  - Mehta, Ashesh D.
A1  - Malach, Rafael
T1  - Increasing suppression of saccade-related transients along the human visual hierarchy
T2  - eLife
N2  - A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed in higher-level but not early visual cortex. Here, we utilized the broad anatomical coverage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabilizing mechanism operates following small saccades. We compared saccades (1.3°−3.7°) initiated during inspection of large individual visual objects with similarly-sized external stimulus displacements. Early visual cortex sites responded with positive transients to both conditions. In contrast, in both dorsal and ventral higher-level sites the response to saccades (but not to external displacements) was suppressed. These findings indicate that early visual cortex is highly unstable compared to higher-level visual regions which apparently constitute the main target of stabilizing extra-retinal oculomotor influences.
KW  - efferent copy
KW  - electrocorticography
KW  - human
KW  - neuroscience
KW  - saccades
KW  - visual cortex
KW  - visual perception
Y1  - 2017
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46499
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-464992
SN  - 2050-084X
N1  - Copyright Golan et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
VL  - 6
IS  - e27819
SP  - 1
EP  - 15
PB  - eLife Sciences Publications
CY  - Cambridge
ER  -