TY - JOUR A1 - Kennedy, Mark A1 - Kreppner, Jana A1 - Knights, Nicky A1 - Kumsta, Robert A1 - Maughan, Barbara A1 - Golm, Dennis A1 - Hill, Jonathan A1 - Rutter, Michael A1 - Schlotz, Wolff A1 - Sonuga-Barke, Edmund T1 - Adult disinhibited social engagement in adoptees exposed to extreme institutional deprivation : examination of its clinical status and functional impact T2 - The British journal of psychiatry N2 - Background: Early-life institutional deprivation produces disinhibited social engagement (DSE). Portrayed as a childhood condition, little is known about the persistence of DSE-type behaviours into, presentation during, and their impact on, functioning in adulthood. Aims: We examine these issues in the young adult follow-up of the English and Romanian Adoptees study. Method: A total of 122 of the original 165 Romanian adoptees who had spent up to 43 months as children in Ceauşescu's Romanian orphanages and 42 UK adoptees were assessed for DSE behaviours, neurodevelopmental and mental health problems, and impairment between ages 2 and 25 years. Results: Young adult DSE behaviour was strongly associated with early childhood deprivation, with a sixfold increase for those who spent more than 6 months in institutions. However, although DSE overlapped with autism spectrum disorder and attention-deficit hyperactivity disorder symptoms it was not, in itself, related to broader patterns of mental health problems or impairments in daily functioning in young adulthood. Conclusions: DSE behaviour remained a prominent, but largely clinically benign, young adult feature of some adoptees who experienced early deprivation. Y1 - 2018 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46735 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-467354 SN - 1472-1465 SN - 0007-1250 N1 - Copyright: © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY) licence. VL - 211 IS - 5 SP - 289 EP - 295 PB - The Royal College of Psychiatrists CY - London ER -