TY  - JOUR
A1  - Frantz, Laurent A. F.
A1  - Haile, James
A1  - Lin, Audrey T.
A1  - Scheu, Amelie
A1  - Geörg, Christina
A1  - Benecke, Norbert
A1  - Alexander, Michelle
A1  - Linderholm, Anna
A1  - Mullin, Victoria E.
A1  - Daly, Kevin G.
A1  - Battista, Vincent M.
A1  - Price, Max
A1  - Gron, Kurt J.
A1  - Alexandri, Panoraia
A1  - Arbogast, Rose-Marie
A1  - Arbuckle, Benjamin
A1  - Bălăşescu, Adrian
A1  - Barnett, Ross
A1  - Bartosiewicz, László
A1  - Baryshnikov, Gennady
A1  - Bonsall, Clive
A1  - Borić, Dušan
A1  - Boroneanţ, Adina
A1  - Bulatović, Jelena
A1  - Çakırlar, Canan
A1  - Carretero, José-Miguel
A1  - Chapman, John
A1  - Church, Mike
A1  - Crooijmans, Richard
A1  - DeCupere, Bea
A1  - Detry, Cleia
A1  - Dimitrijević, Vesna
A1  - Dumitraşcu, Valentin
A1  - Du Plessis, Louis
A1  - Edwards, Ceiridwen
A1  - Erek, Cevdet Merih
A1  - Erim Özdoğan, Aslı
A1  - Ervynck, Anton
A1  - Fulgione, Domenico
A1  - Gligor, Mihai
A1  - Götherström, Anders
A1  - Gourichon, Lionel
A1  - Groenen, Martien A. M.
A1  - Helmer, Daniel
A1  - Hongo, Hitomi
A1  - Horwitz, Liora Kolska
A1  - Irving-Pease, Evan K.
A1  - Lebrasseur, Ophélie
A1  - Lesur, Joséphine
A1  - Malone, Caroline
A1  - Manaserya, Ninna
A1  - Marciniak, Arkadiusz
A1  - Martlew, Holley
A1  - Mashkour, Marjan
A1  - Matthews, Roger
A1  - Motuzaitė Matuzevičiūtė, Giedrė
A1  - Maziar, Sepideh
A1  - Meijaard, Erik
A1  - McGovern, Tom
A1  - Megens, Hendrik-Jan
A1  - Miller, Rebecca
A1  - Mohaseb, Azadeh Fatemeh
A1  - Orschiedt, Jörg
A1  - Orton, David
A1  - Papathanasiou, Anastasia
A1  - Parker Pearson, Michael
A1  - Pinhasi, Ron
A1  - Radmanović, Darko
A1  - Ricaut, François-Xavier
A1  - Richards, Mike
A1  - Sabin, Richard
A1  - Sarti, Lucia
A1  - Schier, Wolfram
A1  - Sheikhi, Shiva
A1  - Stephan, Elisabeth
A1  - Stewart, John R.
A1  - Stoddart, Simon
A1  - Tagliacozzo, Antonio
A1  - Tasić, Nenad N.
A1  - Trantalidou, Katerina
A1  - Tresset, Anne
A1  - Valdiosera, Cristina
A1  - Hurk, Youri van den
A1  - Poucke, Sophie van
A1  - Vigne, Jean-Denis
A1  - Yanevich, Alexander
A1  - Zeeb-Lanz, Andrea
A1  - Triantafyllidis, Alexandros
A1  - Gilbert, M. Thomas P.
A1  - Schibler, Jörg
A1  - Rowley-Conwy, Peter
A1  - Zeder, Melinda
A1  - Peters, Joris
A1  - Cucchi, Thomas
A1  - Bradley, Daniel G.
A1  - Dobney, Keith
A1  - Burger, Joachim
A1  - Evin, Allowen
A1  - Girdland-Flink, Linus
A1  - Larson, Greger
T1  - Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe
T2  - Proceedings of the National Academy of Sciences of the United States of America
N2  - Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in the Near East, and mitochondrial DNA (mtDNA) suggests that pigs arrived in Europe alongside farmers ∼8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local European wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hypotheses, we obtained mtDNA sequences from 2,099 modern and ancient pig samples and 63 nuclear ancient genomes from Near Eastern and European pigs. Our analyses revealed that European domestic pigs dating from 7,100 to 6,000 y BP possessed both Near Eastern and European nuclear ancestry, while later pigs possessed no more than 4% Near Eastern ancestry, indicating that gene flow from European wild boars resulted in a near-complete disappearance of Near East ancestry. In addition, we demonstrate that a variant at a locus encoding black coat color likely originated in the Near East and persisted in European pigs. Altogether, our results indicate that while pigs were not independently domesticated in Europe, the vast majority of human-mediated selection over the past 5,000 y focused on the genomic fraction derived from the European wild boars, and not on the fraction that was selected by early Neolithic farmers over the first 2,500 y of the domestication process.
KW  - domestication
KW  - evolution
KW  - gene flow
KW  - Neolithic
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/50856
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-508567
SN  - 0027-8424
SN  - 1091-6490
VL  - 116
IS  - 35
SP  - 17231
EP  - 17238
PB  - National Acad. of Sciences
CY  - Washington, DC
ER  -