TY - JOUR A1 - Al Naimi, Ammar A1 - Jennewein, Lukas A1 - Mouzakiti, Niki A1 - Louwen, Frank A1 - Bahlmann, Franz T1 - The effect of the onset of labor on the characteristics of the cesarean scar T2 - International journal of gynecology & obstetrics N2 - Objective: To assess the effect of cesarean section (CS) timing, elective versus unplanned, on the residual myometrial thickness (RMT) and CS scars. Methods: This is a prospective single-blinded observational cohort study with 186 observations. Patients indicated to undergo first singleton CS were preoperatively recruited. Exclusion criteria were history of repeated CS, vertical hysterotomy, diabetes, and additional uterine surgeries. Sonographic examination was performed for assessing the RMT ratio, the presence of a niche, fibrosis, and the distance from the scar to the internal os (SO) 1 year after CS. Power analysis was performed with 0.05 α, 0.1 β, and all statistical analyses were conducted with Stata®. Results: Wilcoxon rank-sum test for the association between CS timing, RMT ratio and SO showed Z values of −0.59 and −4.94 (P = 0.553 and P < 0.001), respectively. There was no association between CS timing and niches and fibrosis (P > 0.99 and P = 0.268, respectively). Linear regression between SO and the extent of cervical dilatation showed a −0.45 β (95% confidence interval −0.68 to −0.21) and a 10.22-mm intercept (P < 0.001). Conclusion: RMT is independent of the timing of CS, but the SO distance shows a negative linear relationship with the cervical dilatation. KW - cesarean section KW - niche KW - residual myometrial thickness Y1 - 2021 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63913 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-639134 SN - 1879-3479 N1 - This study was supported by the Dr. Senckenberg Foundation, Frankfurt am Main. N1 - Early View: Online Version before inclusion in an issue N1 - Version of Record: http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hebis:30:3-627782 VL - 2021 IS - online version before inclusion in an issue SP - 1 EP - 5 PB - Wiley CY - Hoboken, NJ ER -