Systematic screening of bryophytes for antitumor agents
- References are made to cytotoxic and/or antitumor compounds that have been isolated - ansamitocin P-3 from Claopodium crispifolium (Hook.) Ren. & Card. and Anomodon attenuatus Hueb., or an associated actinomycete, and ohioensins and pallidisetums from Polytrichum spp. Several hundred collections, which have been obtained from temperate regions of North America during 1990 and 1991, are currently being screened in new bioassays; active sesquiterpene lactones have been recently isolated from species of Porella. The methodologies of collecting and screening bryophyte samples are discussed with consideration to costs based on expected number of samples that might be collected in a day, the diversity in the collections as related to phytogeography and vegetation types, and the bryophyte cover that is vanishing in many forest regions of the United States. The difficulties in obtaining large collections for isolation of active agents are also discussed by examplerecollection of Claopodium crispifolium.
Author: | Richard W. Spjut, David G. I. Kingston, John M. Cassady |
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URN: | urn:nbn:de:hebis:30:3-302312 |
ISSN: | 0935-5626 |
Parent Title (English): | Tropical bryology |
Publisher: | D. Quandt, Univ. Bonn, Nees Inst. für Biodiversität d. Pflanzen |
Place of publication: | Bonn |
Document Type: | Article |
Language: | English |
Year of Completion: | 1992 |
Year of first Publication: | 1992 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2013/07/12 |
Issue: | 6 |
Page Number: | 10 |
First Page: | 193 |
Last Page: | 202 |
Note: | The layout of the electronic version of this contribution differs from the layout of the original version published in the printed volume. |
HeBIS-PPN: | 348855869 |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 58 Pflanzen (Botanik) / 580 Pflanzen (Botanik) |
Sammlungen: | Sammlung Biologie / Sondersammelgebiets-Volltexte |
Zeitschriften / Jahresberichte: | Tropical Bryology / Tropical Bryology, Volume 6 (1992) |
: | urn:nbn:de:hebis:30:3-301399 |
Licence (German): | Deutsches Urheberrecht |