Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link
- The proteasome inhibitor Bortezomib has been identified as a potent enhancer of TRAIL-induced apoptosis in several human cancers. However, the identification of the underlying molecular mechanisms of this synergistic cell death induction has been ongoing over the last years. A recent study identifies a new mechanism of action for the synergism of TRAIL and Bortezomib.
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| Author: | Simone FuldaORCiDGND |
|---|---|
| URN: | urn:nbn:de:hebis:30-102383 |
| URL: | http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=277&path[]=421 |
| DOI: | https://doi.org/10.18632/oncotarget.277 |
| ISSN: | 1949-2553 |
| Parent Title (English): | Oncotarget |
| Publisher: | Impact Journals LLC |
| Place of publication: | [S.l.] |
| Document Type: | Article |
| Language: | English |
| Date of Publication (online): | 2011/05/16 |
| Date of first Publication: | 2011/05/16 |
| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Release Date: | 2011/08/08 |
| Tag: | TRAIL; apoptosis; cancer; chemotherapy; proteasome inhibitor |
| Volume: | 2 |
| Issue: | 5 |
| Page Number: | 4 |
| First Page: | 418 |
| Last Page: | 421 |
| Note: | Copyright: © Fulda. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| HeBIS-PPN: | 272535168 |
| Institutes: | Medizin / Medizin |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Sammlungen: | Universitätspublikationen |
| Licence (German): |  Creative Commons - Namensnennung 3.0 |
