Depressive mood mediates the influence of social support on health-related quality of life in elderly, multimorbid patients

  • Background: It is not well established how psychosocial factors like social support and depression affect health-related quality of life in multimorbid and elderly patients. We investigated whether depressive mood mediates the influence of social support on health-related quality of life. Methods: Cross-sectional data of 3,189 multimorbid patients from the baseline assessment of the German MultiCare cohort study were used. Mediation was tested using the approach described by Baron and Kenny based on multiple linear regression, and controlling for socioeconomic variables and burden of multimorbidity. Results: Mediation analyses confirmed that depressive mood mediates the influence of social support on health-related quality of life (Sobel's p < 0.001). Multiple linear regression showed that the influence of depressive mood (beta = -0.341, p < 0.01) on health-related quality of life is greater than the influence of multimorbidity (beta = -0.234, p < 0.01). Conclusion: Social support influences health-related quality of life, but this association is strongly mediated by depressive mood. Depression should be taken into consideration in research on multimorbidity, and clinicians should be aware of its importance when caring for multimorbid patients.

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Author:Felix Sebastin Wicke, Corina GüthlinGND, Karola Mergenthal, Jochen GensichenORCiDGND, Christin Löffler, Horst Bickel, Wolfgang Maier, Steffi Gerlinde Riedel-Heller, Siegfried Weyerer, Birgitt Wiese, Hans-Helmut König, Gerhard Schön, Heike Hansen, Hendrik van den Bussche, Martin Scherer, Anne Dahlhaus
URN:urn:nbn:de:hebis:30:3-333989
DOI:https://doi.org/10.1186/1471-2296-15-62
ISSN:1471-2296
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/24708815
Parent Title (English):BMC family practice
Publisher:BioMed Central
Place of publication:London
Document Type:Article
Language:English
Date of Publication (online):2014/04/08
Date of first Publication:2014/04/08
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2014/05/07
Tag:Chronic medical conditions; Coping; Depression; Elderly patients; Family practice; Health-related quality of life; Multimorbidity; Primary care; Social support
Volume:15
Issue:62
Page Number:11
Note:
© 2014 Wicke et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
HeBIS-PPN:364480173
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 2.0