Neurophysiological correlates of motor planning and movement initiation in ACL-reconstructed individuals : a case–control study

  • Introduction Current: evidence suggests that the loss of mechanoreceptors after anterior cruciate ligament (ACL) tears might be compensated by increased cortical motor planning. This occupation of cerebral resources may limit the potential to quickly adapt movements to unforeseen external stimuli in the athletic environment. To date, studies investigating such neural alterations during movement focused on simple, anticipated tasks with low ecological validity. This trial, therefore, aims to investigate the cortical and biomechanical processes associated with more sport-related and injury-related movements in ACL-reconstructed individuals. Methods and analysis: ACL-reconstructed participants and uninjured controls will perform repetitive countermovement jumps with single leg landings. Two different conditions are to be completed: anticipated (n=35) versus unanticipated (n=35) successful landings. Under the anticipated condition, participants receive the visual information depicting the requested landing leg prior to the jump. In the unanticipated condition, this information will be provided only about 400 msec prior to landing. Neural correlates of motor planning will be measured using electroencephalography. In detail, movement-related cortical potentials, frequency spectral power and functional connectivity will be assessed. Biomechanical landing quality will be captured via a capacitive force plate. Calculated parameters encompass time to stabilisation, vertical peak ground reaction force, and centre of pressure path length. Potential systematic differences between ACL-reconstructed individuals and controls will be identified in dependence of jumping condition (anticipated/ unanticipated, injured/uninjured leg and controls) by using interference statistics. Potential associations between the cortical and biomechanical measures will be calculated by means of correlation analysis. In case of statistical significance (α<0.05.) further confounders (cofactors) will be considered. Ethics and dissemination: The independent Ethics Committee of the University of Frankfurt (Faculty of Psychology and Sports Sciences) approved the study. Publications in peer-reviewed journals are planned. The findings will be presented at scientific conferences. Trial status: At the time of submission of this manuscript, recruitment is ongoing. Trial registration number: NCT03336060; Pre-results.
Author:Florian GiescheORCiD, Tobias EngeroffORCiDGND, Jan WilkeORCiDGND, Daniel NiedererORCiDGND, Lutz VogtGND, Winfried BanzerGND
Pubmed Id:
Parent Title (English):BMJ open
Publisher:BMJ Publishing Group
Place of publication:London
Document Type:Article
Year of Completion:2018
Date of first Publication:2018/09/19
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2018/09/25
Tag:ACL rupture; central nervous system modifications; cortical activity; neurocognition; neuromuscular function; neuroplasticity
Issue:9, e023048
Page Number:9
First Page:1
Last Page:9
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:
Institutes:Psychologie und Sportwissenschaften / Sportwissenschaften
Wissenschaftliche Zentren und koordinierte Programme / Starker Start ins Studium: Qualitätspakt Lehre
Dewey Decimal Classification:7 Künste und Unterhaltung / 79 Sport, Spiele, Unterhaltung / 790 Freizeitgestaltung, darstellende Künste, Sport
Open-Access-Publikationsfonds:Psychologie und Sportwissenschaften
Licence (English):License LogoCreative Commons - Namensnennung-Nicht kommerziell 4.0