Patent foramen ovale : story closed?

  • The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with an excess of complications in the interventional arm, two large recent trials suggest a benefit with regard of preventing further ischemic strokes. With this discrepancy in results it is important to discuss recent trials in detail and evolve an informed clinical approach for daily practice.

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Author:Martin Köhrmann, Peter Dieter Schellinger, Georgios Tsivgoulis, Thorsten Steiner
URN:urn:nbn:de:hebis:30:3-490821
DOI:https://doi.org/10.5853/jos.2018.03097
ISSN:2287-6391
ISSN:2287-6405
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/30732440
Parent Title (English):Journal of stroke
Publisher:Korean Stroke Society
Place of publication:Seoul
Document Type:Article
Language:English
Year of Completion:2019
Date of first Publication:2019/01/31
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2019/02/19
Tag:Foramen ovale; Intracranial embolism; Stroke; patent
Volume:21
Issue:1
Page Number:8
First Page:23
Last Page:30
Note:
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
HeBIS-PPN:446488569
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (English):License LogoCreative Commons - Namensnennung-Nicht kommerziell 4.0