Prostaglandin e2 labour induction with intravaginal (minprostin) versus intracervical (prepidil) administration at term : randomized study of maternal and neonatal outcome and patient’s perception using the osgood semantic differential scales

  • Aim. To compare the efficacy, safety, and patient’s perception of two prostaglandin E2 application methods for induction of labour. Method. Above 36th weeks of gestation, all women, who were admitted to hospital for induction of labour, were prospectively randomised to intravaginal 1 mg or intracervical 0.5 mg irrespective of cervical Bishop score. The main outcome variables were induction-to-delivery interval, number of foetal blood samples, PDA rate, rate of oxytocin augmentation, rate of vaginal delivery, and patient’s perception using semantic differential questionnaire. Results. Thirty-nine patients were enrolled in this study. There was no statistical significant difference between the two groups in regard to perceptions of induction. The median induction delivery time using intravaginal versus intracervical administration was 29.9 versus 12.8 hours, respectively (). No statistically difference between the groups was detected in regard to parity, gestation age, cervical Bishop score, number of foetal blood samples, PDA rate, rate of oxytocin augmentation, and mode of birth. Summary. Irrespective of the cervical Bishop Score, intracervical gel had a shorter induction delivery time without impingement on the women’s perception of induction.

Download full text files

Export metadata

Author:Joscha Reinhard, Roberta Rösler, Juping Yuan, Sven Schiermeier, Eva HerrmannORCiD, Michael H. R. Eichbaum, Frank LouwenGND
Pubmed Id:
Parent Title (English):BioMed research international
Place of publication:New York [u. a.]
Contributor(s):Louiza Belkacemi
Document Type:Article
Year of Completion:2014
Date of first Publication:2014/12/29
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2019/08/05
Issue:Art. 682919
Page Number:7
First Page:1
Last Page:6
Copyright © 2014 Joscha Reinhard et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 3.0