Maximilian Münchhoff, Helga Mairhofer, Hans Nitschko, Natascha Grzimek-Koschewa, Dieter Hoffmann, Annemarie Berger, Holger Rabenau, Marek Widera, Nikolaus Ackermann, Regina Konrad, Sabine Zange, Alexander Graf, Stefan Krebs, Helmut Blum, Andreas Sing, Bernhard Liebl, Roman Wölfel, Sandra Ciesek, Christian Drosten, Ulrike Protzer, Stephan Böhm, Oliver Till Keppler
- Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. While most assays performed well, we identified detection problems in a commonly used assay that may have resulted in false-negative test results during the first weeks of the pandemic.
Metadaten| Author: | Maximilian Münchhoff, Helga Mairhofer, Hans Nitschko, Natascha Grzimek-Koschewa, Dieter Hoffmann, Annemarie BergerGND, Holger RabenauORCiDGND, Marek WideraORCiDGND, Nikolaus Ackermann, Regina Konrad, Sabine Zange, Alexander Graf, Stefan Krebs, Helmut Blum, Andreas Sing, Bernhard Liebl, Roman Wölfel, Sandra CiesekORCiDGND, Christian DrostenORCiDGND, Ulrike Protzer, Stephan Böhm, Oliver Till KepplerORCiDGND |
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| URN: | urn:nbn:de:hebis:30:3-547349 |
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| DOI: | https://doi.org/10.2807/1560-7917.ES.2020.25.24.2001057 |
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| ISSN: | 1560-7917 |
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| Pubmed Id: | https://pubmed.ncbi.nlm.nih.gov/32583765 |
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| Parent Title (French): | Eurosurveillance |
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| Publisher: | European Centre for Disease Prevention and Control |
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| Place of publication: | Stockholm |
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| Document Type: | Article |
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| Language: | English |
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| Year of Completion: | 2020 |
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| Date of first Publication: | 2020/06/18 |
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| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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| Release Date: | 2020/07/06 |
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| Tag: | COVID-19; PCR; SARS-CoV-2; diagnostic test |
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| Volume: | 25 |
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| Issue: | 24, Art. 2001057 |
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| Page Number: | 5 |
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| First Page: | 1 |
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| Last Page: | 5 |
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| Note: | This work is licensed under a Creative Commons Attribution 4.0 International License. |
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| HeBIS-PPN: | 467551979 |
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| Institutes: | Medizin / Medizin |
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| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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| Sammlungen: | Universitätspublikationen |
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| Licence (German): |  Creative Commons - Namensnennung 4.0 |
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Creative Commons - Namensnennung 4.0