Investigation of non-canonical terpene biosynthesis

  • Terpenes are one of the largest and most diverse class of natural products, produced by organisms from all kingdoms of life and with important applications in the pharma, flavor and fragrance industries. Well-known examples of terpenes are the pharmaceuticals artemisinin and taxol, the flavor and fragrance compounds menthol, santalol and sclareol, the structural material polyisoprene and the biofuel precursor farnesene. The methods and results presented in this work offer a variety of ways to modify terpene precursors for the creation of new terpene molecules. The application of these methodologies in well-established production systems could lead to the production of new substances, with applications in the industrial fields of pharmaceuticals, flavors and fragrances, and biofuels.

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Metadaten
Author:Laura Drummond
URN:urn:nbn:de:hebis:30:3-640803
DOI:https://doi.org/10.21248/gups.64080
ISBN:978-3-8440-8226-5
Parent Title (German):Schriftenreihe des DECHEMA-Forschungsinstituts ; 25
Publisher:Shaker Verlag
Place of publication:Düren
Referee:Eckhard Boles, Jens Schrader
Document Type:Doctoral Thesis
Language:English
Date of Publication (online):2021/11/12
Date of first Publication:2021/10/27
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Granting Institution:Johann Wolfgang Goethe-Universität
Date of final exam:2021/07/21
Release Date:2021/11/12
Tag:Methyltransferase; Microbiology; Non-canonical terpenes; Prenyl pyrophosphates; Terpenes
Page Number:212
HeBIS-PPN:487689127
Institutes:Biowissenschaften
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Sammlungen:Universitätspublikationen
Sammlung Biologie / Biologische Hochschulschriften (Goethe-Universität)
Licence (German):License LogoDeutsches Urheberrecht