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Angular distributions for elastic and inelastic transitions in 20Ne + 16O scattering have been measured at E(20Ne)=50 MeV. For the 0+, 2+, and 4+ members of the 20Ne ground-state rotational band, the angular distributions exhibit pronounced backward peaking characteristic of an alpha -cluster exchange mechanism. The analysis of the ground-state transition in the first-order elastic transfer model yields no satisfactory fit although microscopic cluster form factors and full recoil corrections are employed. A coupled channels calculation for the 0+, 2+, and 4+ transitions reveals very strong coupling effects, indicating that the coherent superposition of first-order optical model and distorted-wave Born-approximation amplitudes may not be an adequate model for these reactions. NUCLEAR REACTIONS 16O(20Ne, 16O) and 16O(20Ne, 20Ne), elastic and inelastic transfer; E=50MeV; measured sigma (Ef , theta ); optical model + DWBA, and CCBA analyses.