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By replacing the irises in an electron linac by a slit one gets a structure capable of focussing/defocussing an electron beam (rf-quadrupoles). Therefore one can think of a combination of rf- and conventional magnetic quadrupoles for transversal focussing in linear-colliders. Furthermore they can meet the demands of BNS-damping without initial energy spread. Considering multibunch-operation of a collider, the long-range wake behaviour of this kind of structure has to be investigated. A three-cell structure has been built and investigated for dipole-type transversal long-range wakes. The experimental results are compared to numerical simulations done with MAFIA.
Mode propagation in an iris type accelerator section loaded with single heavily HOM-damped cells
(1994)
The wakefield effects in accelerator sections for future linear colliders will be reduced either by damping by detuning or by a combination of both. For the DESY/THD linac [1] it is forseen to employ heavily HOM-damped cells to provide a strong coupling to the TE/TM11-dipole passband as well as to the TM/TE11-dipole passband. For our experiments we have used wall-slotted damping cells. This leads to several problems concerning the propagation of fundamental and HOM-modes. Experimental investigations have been done. Results are presented.
The effect of a single HOM-damper cell within a channel of undamped cells is described theoretically using an equivalent circuit model. From this a simple equation can be derived which relates the Q-value of the single damping-cell, the bandwidth of the passband under consideration, and the additional phase shift which is introduced by the damper cell to provide energy flow into the damper cell. This equation immediately shows the limitations of such single cell damping systems. Comparisons with experimental results are shown.
The operation of a Free Electron Laser (FEL) in the ultraviolet or in the X-ray regime requires the acceleration of electron bunches with an rms length of 25 to 50 mikrometer. The wakefields generated by these sub picosecond bunches extend into the frequency range well beyond the threshold for Cooper pair breakup (about 750 GHz) in superconducting niobium at 2 K. It is shown, that the superconducting cavities can indeed be operated with 25 mikrometer bunches without suffering a breakdown of superconductivity (quench), however at the price of a reduced quality factor and an increased heat transfer to the superfluid helium bath. This was first shown by wakefield calculations based on the diffraction model [1]. In the meantime a more conventional method of computing wake fields in the time domain by numerical methods was developed and used for the wakefield calculations [2]. Both methods lead to comparable results: the operation of TESLA with 25 mikrometer bunches is possible but leads to an additional heat load due to the higher order modes (HOMs). Therefore HOM dampers for these high frequencies are under construction [3]. These dampers are located in the beam pipes between the 9-cell cavities. So it is of interest, if there are trapped modes in the cavity due to closed photon orbits. In this paper we investigate the existence of trapped modes and the distribution of heat load over the surface of the TESLA cavity by numerical photon tracking.
A new method for measuring quality factors in cavities is presented. This method is capable of measuring Q-factors in heavily damped as well as in undamped cavities. In addition, the possibility of separating overlapping modes and measuring their Q-factors is provided. Measurements on HOM (higher order mode) damped cavities for the DESY/THD linear collider project are presented
Determination of field strength and quality factor of heavily HOM damped accelerator cavities
(1992)
Two methods of of measuring field strength in accelerator cavities, heavily damped with respect to higher order modes (HOM), are presented. From the results of the field measurements the coupling (damping) factor and thus the quality factor of the damped resonator can be derived. Measurements of a pillbox resonator with heavily damped TM110-mode (Q < 20) demonstrate the usefulness of the techniques presented, even in this extreme range.
Accelerating cavities exchange HOM power through interconnecting beam pipes in case of signal frequencies above the cut-off of their propagating waveguide modes. This may lead either to improved HOM damping or - in the case most severe - to unwanted phase coherence of fields to the beam. Therefore the knowledge of the scattering properties of a cavity as a line element is needed to analyse all kinds of RF cavity-cavity interaction. Since there is a lack of measurement tools capable to provide a multidimensional scattering matrix at a given frequency point, we have been developing a method for this purpose. It uses a set of 2-port S-parameters of the device under test, embedded in a number of geometrically different RF environments. The application of the method is demonstrated with copper models of TESLA cavities.
Introduction: The German PID-NET registry was founded in 2009, serving as the first national registry of patients with primary immunodeficiencies (PID) in Germany. It is part of the European Society for Immunodeficiencies (ESID) registry. The primary purpose of the registry is to gather data on the epidemiology, diagnostic delay, diagnosis, and treatment of PIDs.
Methods: Clinical and laboratory data was collected from 2,453 patients from 36 German PID centres in an online registry. Data was analysed with the software Stata® and Excel.
Results: The minimum prevalence of PID in Germany is 2.72 per 100,000 inhabitants. Among patients aged 1–25, there was a clear predominance of males. The median age of living patients ranged between 7 and 40 years, depending on the respective PID. Predominantly antibody disorders were the most prevalent group with 57% of all 2,453 PID patients (including 728 CVID patients). A gene defect was identified in 36% of patients. Familial cases were observed in 21% of patients. The age of onset for presenting symptoms ranged from birth to late adulthood (range 0–88 years). Presenting symptoms comprised infections (74%) and immune dysregulation (22%). Ninety-three patients were diagnosed without prior clinical symptoms. Regarding the general and clinical diagnostic delay, no PID had undergone a slight decrease within the last decade. However, both, SCID and hyper IgE- syndrome showed a substantial improvement in shortening the time between onset of symptoms and genetic diagnosis. Regarding treatment, 49% of all patients received immunoglobulin G (IgG) substitution (70%—subcutaneous; 29%—intravenous; 1%—unknown). Three-hundred patients underwent at least one hematopoietic stem cell transplantation (HSCT). Five patients had gene therapy.
Conclusion: The German PID-NET registry is a precious tool for physicians, researchers, the pharmaceutical industry, politicians, and ultimately the patients, for whom the outcomes will eventually lead to a more timely diagnosis and better treatment.