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Uniqueness and Lipschitz stability in electrical impedance tomography with finitely many electrodes
(2019)
For the linearized reconstruction problem in electrical impedance tomography with the complete electrode model, Lechleiter and Rieder (2008 Inverse Problems 24 065009) have shown that a piecewise polynomial conductivity on a fixed partition is uniquely determined if enough electrodes are being used. We extend their result to the full non-linear case and show that measurements on a sufficiently high number of electrodes uniquely determine a conductivity in any finite-dimensional subset of piecewise-analytic functions. We also prove Lipschitz stability, and derive analogue results for the continuum model, where finitely many measurements determine a finite-dimensional Galerkin projection of the Neumann-to-Dirichlet operator on a boundary part.
In this paper we deal with an implementation as well as numerical experiments for the coupling of interior and exterior problems of the elastodynamic wave equation with transparent boundary conditions in 3D as described in a previous paper by this author. In more detail, the FEM‐BEM‐coupling as well as the time discretization by using leapfrog and convolution quadrature is considered. Our aim is to provide an insight into the necessary steps of the implementation. Based on this, we present numerical experiments for a non‐convex domain and analyze the errors.
In vivo functional diversity of midbrain dopamine neurons within identified axonal projections
(2019)
Functional diversity of midbrain dopamine (DA) neurons ranges across multiple scales, from differences in intrinsic properties and connectivity to selective task engagement in behaving animals. Distinct in vitro biophysical features of DA neurons have been associated with different axonal projection targets. However, it is unknown how this translates to different firing patterns of projection-defined DA subpopulations in the intact brain. We combined retrograde tracing with single-unit recording and labelling in mouse brain to create an in vivo functional topography of the midbrain DA system. We identified differences in burst firing among DA neurons projecting to dorsolateral striatum. Bursting also differentiated DA neurons in the medial substantia nigra (SN) projecting either to dorsal or ventral striatum. We found differences in mean firing rates and pause durations among ventral tegmental area (VTA) DA neurons projecting to lateral or medial shell of nucleus accumbens. Our data establishes a high-resolution functional in vivo landscape of midbrain DA neurons.