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Europeana provides a common access point to digital cultural heritage objects across different cultural domains among which the libraries. The recent development of the Europeana Data Model (EDM) provide new ways for libraries to experiment with Linked Data. Indeed the model is designed as a framework reusing various wellknown standards developed in the Semantic Web Community, such as the Resource Description Framework (RDF), the OAI Object Reuse and Exchange (ORE), and Dublin Core namespaces. It provides new opportunities for libraries to provide rich and interlinked metadata to the Europeana aggregation.
However to be able to provide data to Europeana, libraries need to create mappings from the librarystandard to EDM. This step involves decisions based on domainspecific requirements and on the possibilities offered by EDM. The crossdomain nature of EDM limiting in some cases the completeness of the mappings, extension of the model have been proposed to accommodate the library needs.
The "Digitised Manuscripts to Europeana" project (DM2E) has created an extension of EDM to optimise the mappings of librarydata for manuscripts. This extension is in the form of subclasses and subproperties that further specialise EDM concepts and properties. It includes spatial creation and publishing information, specific contributor and publication type properties and more.
Furthermore the granularity of the mapping has been extended to allow references and annotations on page level as required for scholarly work. As part of this project the metadata of the Hebrew Manuscripts as well as of the Medieval Manuscripts presented in the Digital Collections of the Frankfurt University Library have been mapped to this extension. This includes links to the Integrated Authority File (GND) of the German National Library with further links to the Virtual International Authority File (VIAF).
Based on this development a new comprehensive mapping from the digitalisation metadata format METS/MODS to EDM has been established for all materials of the Frankfurt Judaica in "Judaica Europeana ". It demonstrates today’s capabilities of the creation of linked Data structures in Europeana based on library catalogue data and structural data from the digitalisation process.
Vom 27. Juli bis 05. August 2014 veranstaltete die Akademie BURG FÜRSTENECK die 4. Hessische Schülerakademie für die Mittelstufe (Jgs. 7-9). Es gibt nichts Schöneres als Ferien! Das dachten sicher auch die 60 zwölf- bis fünfzehnjährigen Schülerinnen und Schüler, die sich in den alten Burgmauern trafen. Allerdings entschieden sie sich nach einer aufwändigen Bewerbung dafür, einen Teil ihrer Sommerferien „ganz anders“ zu verbringen. Neugierig und voller Wissensdurst beschäftigten sich die vielfältig begabten jungen Menschen in den Hauptkursen mit folgenden Themen: Zaubern in der Chemie, geheimnisvollen Botschaften in der Mathematik, der Entdeckung des Lebensraums Baum in Biologie, überraschenden Experimenten in der Physik und den Facetten des Teenageralltags, dargestellt im Kurs Kunst und Kultur.
Die Hessische Schülerakademie 2014 stand ganz im Zeichen ihres 10jährigen Bestehens. Seit Gründung der Oberstufenakademie im Jahre 2004 durch Cynthia Hog-Angeloni und Wolfgang Metzler hat sich die "HSAKA" selbstverständlich verändert; das ist bei einem so ambitionierten Projekt auch gar nicht anders denkbar. Die Hessische Schülerakademie hat sich behauptet, indem sie immer wieder neue Impulse aufgenommen und sich beständig um Verbesserung bemüht hat – und sie ist gewachsen.
Cultural heritage reconstructed - Compact Memory and the Frankfurt Digital Judaica Collection
(2014)
Compact Memory, the internet archive of German Jewish periodicals, provides free global internet access to the vast majority of German-Jewish newspapers and periodicals of the 19th and 20th century.
Jewish historical newspapers are the invaluable sources that supply direct and detailed information of the transformation process of Jewry and offer new insights into European Jewish history. The use of these historical sources however is extremely difficult, as complete sets of periodicals are very rarely to be found and they are scattered all over the world in different libraries and archives and in different physical formats (paper, microfilm).
Compact Memory contains the 110 most important Jewish German newspapers and periodicals in Central Europe in the period from 1806-1938, covering the complete range of religious, political, social, cultural and academic aspects of Jewish life. The texts are available partly as full-texts, processed by OCR, partly as graphic documents with corresponding index options. The database offers advanced search options, downloading and printing of articles. Thousands of essays of more than 10.000 individual contributors have been bibliographically indexed.
Compact Memory was established by the Judaica Division of the University Library Frankfurt am Main and in charge today in cooperation with the Aachen Chair of German-Jewish Literary History and the Cologne library Germania Judaica.
Compact Memory is one database within the Digital Collection Judaica which being part of Europeana and other digital portals offers resources for the reconstruction and representation of Jewish cultural heritage.
XIII Nuclei in the Cosmos, 7-11 July, 2014 Debrecen, Hungary.
As an alternative production scenario to the so-called g process, the most abundant p nucleus 92Mo may be produced by a chain of proton-capture reactions in supernovae type Ia. The reactions 90Zr(p,g) and 91Nb(p,g) are the most important reactions in this chain. We have measured the first reaction using high-resolution in-beam g-spectroscopy at HORUS, Cologne, Germany, to contribute to the existing experimental data base. So far, we only investigated the high-energy part of the Gamow window and the analysis is still in progress. We plan to study the second reaction in standard kinematics at the FRANZ facility, Frankfurt, Germany. Current developments at FRANZ will be explained in detail.
We present the results of two-pion production in tagged quasi-free np collisions at a deutron incident beam energy of 1.25 GeV/c measured with the High-Acceptance Di-Electron Spectrometer (HADES) installed at GSI. The specific acceptance of HADES allowed for the first time to obtain high-precision data on π+π− and π−π0 production in np collisions in a region corresponding to large transverse momenta of the secondary particles. The obtained differential cross section data provide strong constraints on the production mechanisms and on the various baryon resonance contributions (∆∆, N(1440), N(1520), ∆(1600)). The invariant mass and angular distributions from the np → npπ+π −and np → ppπ−π0 reactions are compared with different theoretical model predictions.
We have measured the radiative neutron-capture cross section and the total neutron-induced cross section of one of the most important isotopes for the s process, the 25Mg. The measurements have been carried out at the neutron time-of-flight facilities n_TOF at CERN (Switzerland) and GELINA installed at the EC-JRC-IRMM (Belgium). The cross sections as a function of neutron energy have been measured up to approximately 300 keV, covering the energy region of interest to the s process. The data analysis is ongoing and preliminary results show the potential relevance for the s process.
We discuss recent applications of the partonic perturbative QCD based cascade model BAMPS with focus on heavy-ion phenomenology in the hard and soft momentum range. First, the elliptic flow and suppression of charm and bottom quarks are studied at LHC energies. Thereafter, we compare in a detailed study the standard Gunion-Bertsch approximation of the matrix elements for inelastic processes to the exact results in leading order perturbative QCD. Since a disagreement is found, we propose an improved Gunion-Bertsch matrix element, which agrees with the exact result in all phase space regions.
We investigate the properties of the QCD matter across the deconfinement phase transition. In the scope of the parton-hadron string dynamics (PHSD) transport approach, we study the strongly interacting matter in equilibrium as well as the out-of equilibrium dynamics of relativistic heavy-ion collisions. We present here in particular the results on the electromagnetic radiation, i.e. photon and dilepton production, in relativistic heavy-ion collisions and the relevant correlator in equilibrium, i.e. the electric conductivity. By comparing our calculations for the heavy-ion collisions to the available data, we determine the relative importance of the various production sources and address the possible origin of the observed strong elliptic flow ν2 of direct photons.
We present results for calculating fusion cross-sections using a new microscopic approach based on a time-dependent density-constrained DFT calculations. The theory is implemented by using densities and other information obtained from TDDFT time-evolution of the nuclear system as a constraint on the density for DFT calculations.
Aims: We have provided evidence in former studies that cytokines (IL-8, TNF alpha, LBP, TGFß) measured in blood correlate negatively with lung function in deltaF508 homozygous patients. GAP junction proteins might be of importance for the influx of blood cells into the lung. Our aim was to assess the relationship between connexin genotypes and cytokines (IL-8, TNF-alpha, LBP, TGFß) in induced sputum and serum, and lung disease.
Methods: 36 patients homozygous for deltaF508 (median age 18 y, m/f 16/20, FEV1(%) 77) were examined. Sequence analysis was performed for genes encoding GAP junction protein alpha 1 (GJA1/connexin 43) and gap junction protein alpha 4 (GJA4/connexin 37). Cytokines were assessed in serum and induced sputum (IS) by chemiluminescence (DPC Biermann, Bad Homburg, Germany) as well as leukocyte counts.
Results: DNA analysis was performed in 35 patients. Whereas GJA1 showed only one rare heterozygous synonymous SNP (rs138386744) in one patient, four common SNPs were detected in GJA4. Two were synonymous changes, but the third variant (rs41266431) predicts an amino acid substitution (GTA → valine, ATA → isoleucine) as well as the fourth SNP (rs1764391: CCC→proline, TCC→serine). For rs41266431 patients with homozygosity for the G variant had higher IL-8 levels (median: 13.3/8.0 pg/ml, p=0.07) in serum as well as leukocytes in sputum (median: 2050/421 /µl p=0.041) than those showing heterozygosity (G/A). In individuals > 30 years lung function (FEV1 41.3/84.83 % predicted, p=0.07) was worse.
Conclusion: SNP rs41266431 seems a promising candidate for further investigations, suggesting GJA4 a potential disease modifying gene.
Modeling the effects of neuronal morphology on dendritic chloride diffusion and GABAergic inhibition
(2014)
Poster presentation at the Twenty Third Annual Computational Neuroscience Meeting: CNS*2014 Québec City, Canada. 26-31 July 2014.
Gamma-aminobutyric acid receptors (GABAARs) are ligand-gated chloride (Cl−) channels which mediate the majority of inhibitory neurotransmission in the CNS. Spatiotemporal changes of intracellular Cl− concentration alter the concentration gradient for Cl− across the neuronal membrane and thus affect the current flow through GABAARs and the efficacy of GABAergic inhibition. However, the impact of complex neuronal morphology on Cl− diffusion and the redistribution of intracellular Cl− is not well understood. Recently, computational models for Cl− diffusion and GABAAR-mediated inhibition in realistic neuronal morphologies became available [1-3]. Here we have used computational models of morphologically complex dendrites to test the effects of spines on Cl− diffusion. In all dendritic morphologies tested, spines slowed down longitudinal Cl− diffusion along dendrites and decreased the amount and spatial spread of synaptically evoked Cl− changes. Spine densities of 2-10 spines/µm decreased the longitudinal diffusion coefficient of Cl− to 80-30% of its value in smooth dendrites, respectively. These results suggest that spines are able to limit short-term ionic plasticity [4] at dendritic GABAergic synapses.