Refine
Year of publication
- 2001 (153) (remove)
Document Type
- Article (153) (remove)
Language
- English (153) (remove)
Has Fulltext
- yes (153)
Keywords
- Englisch (6)
- Polnisch (4)
- Metapher (2)
- Zweitsprachenerwerb (2)
- 16S mtDNA (1)
- 16S rRNA (1)
- 1st order liquid–gas phase transition (1)
- 2-deoxy-D-ribose (1)
- Alzheimer’s disease (1)
- Amerikanisches Englisch (1)
Institute
- Medizin (19)
- Physik (13)
- Institut für Deutsche Sprache (IDS) Mannheim (11)
- Informatik (5)
- Mathematik (4)
- Biowissenschaften (3)
- Georg-Speyer-Haus (3)
- Extern (2)
- Pharmazie (2)
- Rechtswissenschaft (2)
We have analyzed a series of eleven mutations in the 49-kDa protein of mitochondrial complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica to identify functionally important domains in this central subunit. The mutations were selected based on sequence homology with the large subunit of [NiFe] hydrogenases. None of the mutations affected assembly of complex I, all decreased or abolished ubiquinone reductase activity. Several mutants exhibited decreased sensitivities toward ubiquinone-analogous inhibitors. Unexpectedly, seven mutations affected the properties of iron-sulfur cluster N2, a prosthetic group not located in the 49-kDa subunit. In three of these mutants cluster N2 was not detectable by electron-paramagnetic resonance spectroscopy. The fact that the small subunit of hydrogenase is homologous to the PSST subunit of complex I proposed to host cluster N2 offers a straightforward explanation for the observed, unforeseen effects on this iron-sulfur cluster. We propose that the fold around the hydrogen reactive site of [NiFe] hydrogenase is conserved in the 49-kDa subunit of complex I and has become part of the inhibitor and ubiquinone binding region. We discuss that the fourth ligand of iron-sulfur cluster N2 missing in the PSST subunit may be provided by the 49-kDa subunit.
A checklist of the world species of Limnichidae (35 genera, 345 species) and Lutrochidae (1 genus, 11 species) is presented. The author, year of publication and page number, synonyms, distribution by country, and a terminal bibliography are given for each genus and species. Biological information is also reviewed.
Depth hermeneutics—as developed by LORENZER within the framework of the Frankfort School's program of critical social research—represents a methodological and systematic approach to psychoanalytic research. The new ways and means by which a neo-Nazi utilises his visit to the Auschwitz Memorial to arouse further anti-Semitism are to be investigated by means of a scene-by-scene interpretation of his filmed appearances—first as a good-mooded tourist, then as a volatile right-wing extremist, as competent expert, and as rebellious adolescent. The aim is to demonstrate how the meaning of these role plays develops within the tension between a manifest and a latent significance. The results of this process of interpretations form the basis for clarifying the question: what patterns of socialisation are used by this "yuppie-neo-Nazi" to fascinate particularly adolescents?? In conclusion, the way in which through his post-modern film-production the producer turns Auschwitz into a test-ground where the neo-Nazi can do "a merry dance on the volcano", is analysed.
A new family Coryphoridae is proposed in the superfamily Ephemerelloidea for the monotypic genus Coryphorus. Characters that distinguish Coryphoridae from all other Ephemerelloidea are discussed. The male imago, male subimago, female imago, and egg of Coryphorus aquilus Peters are described for the first time.
A new key is presented to separate adults of the four currently-recognized species of the genus Cradytes Casey (Insecta: Coleoptera: Melyridae): C. longicollis Casey, C. serricollis (LeConte), C. serrulatus . (LeConte), and C. ursinus Blaisdell. The inaccurate statements in an earlier key to species of Cradytes are discussed.