Refine
Year of publication
Document Type
- Preprint (1136) (remove)
Has Fulltext
- yes (1136)
Is part of the Bibliography
- no (1136)
Keywords
- Kollisionen schwerer Ionen (33)
- heavy ion collisions (27)
- Quark-Gluon-Plasma (14)
- equation of state (13)
- QGP (12)
- quark-gluon plasma (10)
- Quark Gluon Plasma (9)
- quark (9)
- Hadron (8)
- Meson (8)
Institute
- Physik (1136) (remove)
We discuss gapless colour superconductivity for neutral quark matter in β equilibrium at zero as well as at nonzero temperature. Basic properties of gapless superconductors are reviewed. The current progress and the remaining problems in the understanding of the phase diagram of strange quark matter are discussed.
Topological semimetal antiferromagnets provide a rich source of exotic topological states which can be controlled by manipulating the orientation of the Néel vector, or by modulating the lattice parameters through strain. We investigate via ab initio density functional theory calculations, the effects of shear strain on the bulk and surface states n two antiferromagnetic EuCd2As2 phases with out-of-plane and in-plane spin configurations. When magnetic moments are along the c-axis, a 3% longitudinal or diagonal shear strain can tune the Dirac semimetal phase to an axion insulator phase, characterized by the parity-based invariant η4I=2. For an in-plane magnetic order, the axion insulator phase remains robust under all shear strains. We further find that for both magnetic orders, the bulk gap increases and a surface gap opens on the (001) surface up to 16 meV. Because of a nonzero η4I index and gapped states on the (001) surface, hinge modes are expected to happen on the side surface states between those gapped surface states. This result can provide a valuable insight in the realization of the long-sought axion states.
We study the phase diagram of a generalized chiral SU(3)-flavor model in mean-field approxi- mation. In particular, the influence of the baryon resonances, and their couplings to the scalar and vector fields, on the characteristics of the chiral phase transition as a function of temperature and baryon-chemical potential is investigated. Present and future finite-density lattice calculations might constrain the couplings of the fields to the baryons. The results are compared to recent lattice QCD calculations and it is shown that it is non-trivial to obtain, simultaneously, stable cold nuclear matter.
The space-time dynamics and pion-HBT radii in central heavy ion-collisions at CERN-SPS and BNL-RHIC are investigated within a hydrodynamic simulation. The dependence of the dynamics and the HBT-parameters on the EoS is studied with different parametrizations of a chiral SU(3) sigma omega model. The selfconsistent collective expansion includes the e ects of e ective hadron masses, generated by the nonstrange and strange scalar condensates. Different chiral EoS show di erent types of phase transitions and even a crossover. The influence of the order of the phase transition and of the latent heat on the space-time dynamics and pion-HBT radii is studied. A small latent heat, i.e. a weak first-order chiral phase transition, or a smooth crossover lead to distinctly di erent HBT predictions than a strong first order phase transition. A quantitative description of the data, both at SPS energies as well as at RHIC energies, appears di cult to achieve within the ideal hydrodynamic approach using the SU(3) chiral EoS. A strong first-order quasi-adiabatic chiral phase transition seems to be disfavored by the pion-HBT data from CERN-SPS and BNL-RHIC.
The measured particle ratios in central heavy-ion collisions at RHIC-BNL are investigated within a chemical and thermal equilibrium chiral SU(3) theta - omega approach. The commonly adopted noninteracting gas calculations yield temperatures close to or above the critical temperature for the chiral phase transition, but without taking into account any interactions. Contrary, the chiral SU(3) model predicts temperature and density dependent e ective hadron masses and e ective chemical potentials in the medium and a transition to a chirally restored phase at high temperatures or chemical potentials. Three di erent parametrizations of the model, which show di erent types of phase transition behaviour, are investigated. We show that if a chiral phase transition occured in those collisions, freezing of the relative hadron abundances in the symmetric phase is excluded by the data. Therefore, either very rapid chemical equilibration must occur in the broken phase, or the measured hadron ratios are the outcome of the dynamical symmetry breaking. Furthermore, the extracted chemical freeze-out parameters di er considerably from those obtained in simple noninteracting gas calculations. In particular, the three models yield up to 35 MeV lower temperatures than the free gas approximation. The in-medium masses turn out di er up to 150 MeV from their vacuum values.
A nonlinear chiral SU(3) approach including the spin 3 2 decuplet is developed to describe dense matter. The coupling constants of the baryon resonances to the scalar mesons are determined from the decuplet vacuum masses and SU(3) symmetry relations. Di erent methods of mass generation show significant differences in the properties of the spin- 3 2 particles and in the nuclear equation of state
Introduction: Until now it is not possible to determine the equation of state (EOS) of hadronic matter from QCD. One succesfully applied alternative way to describe the hadronic world at high densities and temperatures are effective models like the RMF-models [1], where the relevant degrees of freedom are baryons and mesons instead of quarks and gluons. Since approximate chiral symmetry is an essential feature of QCD, it should be a useful concept for building and restricting e ective models. It has been shown [2,3] that effective sigma-omega models including SU(2) chiral symmetry are able to obtain a reasonable description of nuclear matter and finite nuclei. Recently [4] we have shown that an extended SU(3) × SU(3) chiral sigma-omega model is able to describe nuclear matter ground state properties, vacuum properties and finite nuclei satisfactorily. This model includes the lowest SU(3) multiplets of the baryons (octet and decuplet[5]), the spin-0 and the spin-1 mesons as the relevant degrees of freedom. Here we will discuss the predictions of this model for dense, hot, and strange hadronic matter.
A significant drop of the vector meson masses in nuclear matter is observed in a chiral SU(3) model due to the e ects of the baryon Dirac sea. This is taken into account through the summation of baryonic tadpole diagrams in the relativistic Hartree approximation. The appreciable decrease of the in-medium vector meson masses is due to the vacuum polarisation e ects from the nucleon sector and is not observed in the mean field approximation.
Compelling evidence for a new form of matter has been claimed to be formed in Pb+Pb collisions at SPS. We critically review two suggested signatures for this new state of matter: First the suppression of the J/psi , which should be strongly suppressed in the QGP by two different mechanisms, the color-screening [1] and the QCD-photoe ect [2]. Secondly the measured particle, in particular strange hadronic, ratios might signal the freeze-out from a quark-gluon phase.
Compelling evidence for the creation of a new form of matter has been claimed to be found in Pb+Pb collisions at SPS. We discuss the uniqueness of often proposed experimental signatures for quark matter formation in relativistic heavy ion collisions. It is demonstrated that so far none of the proposed signals like J/psi meson production/suppression, strangeness enhancement, dileptons, and directed flow unambigiously show that a phase of deconfined matter has been formed in SPS Pb+Pb collisions. We emphasize the need for systematic future measurements to search for simultaneous irregularities in the excitation functions of several observables in order to come close to pinning the properties of hot, dense QCD matter from data.
Elliptic flow analysis at RHIC with the Lee-Yang Zeroes method in a relativistic transport approach
(2006)
The Lee-Yang zeroes method is applied to study elliptic flow (v_2) in Au+Au collisions at sqrt s =200 A GeV, with the UrQMD model. In this transport approach, the true event plane is known and both the nonflow effects and event-by-event v_2 fluctuations exist. Although the low resolutions prohibit the application of the method for most central and peripheral collisions, the integral and differential elliptic flow from the Lee-Yang zeroes method agrees with the exact v_2 values very well for semi-central collisions.
The cumulant method is applied to study elliptic flow (v_2) in Au+Au collisions at sqrt s=200 AGeV, with the UrQMD model. In this approach, the true event plane is known and both the non-flow effects and event-by-event spatial (epsilon) and v_2 fluctuations exist. Qualitatively, the hierarchy of v_2 's from two, four and six-particle cumulants is consistent with the STAR data, however, the magnitude of v_2 in the UrQMD model is only 60% of the data. We find that the four and six-particle cumulants are good measures of the real elliptic flow over a wide range of centralities except for the most central and very peripheral events. There the cumulant method is affected by the v_2 fluctuations. In mid-central collisions, the four and six-particle cumulants are shown to give a good estimation of the true differential v_2, especially at large transverse momentum, where the two-particle cumulant method is heavily affected by the non-flow effects.
We propose to measure correlations of heavy-flavor hadrons to address the status of thermalization at the partonic stage of light quarks and gluons in high-energy nuclear collisions, shown on the example of azimuthal correlations of D-Dbar pairs. We show that hadronic interactions at the late stage can not disturb these correlations significantly. Thus, a decrease or the complete absence of these initial correlations indicates frequent interactions of heavy-flavor quarks in the partonic stage. Therefore, early thermalization of light quarks is likely to be reached. PACS numbers: 25.75.-q
A canonical partition function for the two-component excluded volume model is derived, leading to two di erent van der Waals approximations. The one is known as the Lorentz-Berthelot mixture and the other has been proposed recently. Both models are analysed in the canonical and grand canonical ensemble. In comparison with the one-component van der Waals excluded volume model the suppression of particle densities is reduced in these two-component formulations, but in two essentially di erent ways. Presently used multi-component models have no such reduction. They are shown to be not correct when used for components with di erent hard-core radii. For high temperatures the excluded volume interaction is refined by accounting for the Lorentz contraction of the spherical excluded volumes, which leads to a distinct enhancement of lighter particles. The resulting e ects on pion yield ratios are studied for AGS and SPS data.
The properties of strange hadronic matter are studied in the context of the modified quark-meson coupling model using two substantially di erent sets of hyperon-hyperon (Y Y ) interactions. The first set is based on the Nijmegen hard core potential model D with slightly attractive Y Y interactions. The second potential set is based on the recent SU(3) extension of the Nijmegen soft-core potential NSC97 with strongly attractive Y Y interactions which may allow for deeply bound hypernuclear matter. The results show that, for the first potential set, the hyperon does not appear at all in the bulk at any baryon density and for all strangeness fractions. The binding energy curves of the resulting N system vary smoothly with density and the system is stable (or metastable if we include the weak force). However, the situation is drastically changed when using the second set where the hyperons appear in the system at large baryon densities above a critical strangeness fraction. We find strange hadronic matter undergoes a first order phase transition from a N system to a N for strangeness fractions fS > 1.2 and baryonic densities exceeding twice ordinary nuclear matter density. Furthermore, it is found that the system built of N is deeply bound. This phase transition a ects significantly the equation of state which becomes much softer and a substantial drop in energy density and pressure are detected as the phase transition takes place. PACS:21.65.+f, 24.85.+p, 12.39Ba
Hot hypernuclear matter is investigated in an explicit SU(3) quark model based on a mean field description of nonoverlapping baryon bags bound by the self-consistent exchange of scalar sigma, zeta and vector omega,phi mesons. The sigma, omega mean fields are assumed to couple to the u, d-quarks while the zeta ,phi mean fields are coupled to the s-quark. The coupling constants of the mean fields with the quarks are assumed to satisfy SU(6) symmetry. The calculations take into account the medium dependence of the bag parameter on the scalar fields sigma, zeta. We consider only the octet baryons N,Lambda,Sigma, Xi in hypernuclear matter. An ideal gas of the strange mesons K and K is introduced to keep zero net strangeness density. Our results for symmetric hypernuclear matter show that a phase transition takes place at a critical temperature around 180 MeV in which the scalar mean fields sigma, zeta take nonzero values at zero baryon density. Furthermore, the bag contants of the baryons decrease significantly at and above this critical temperature indicating the onset of quark deconfinement. The present results imply that the onset of quark deconfinement in SU(3) hypernuclear matter is much stronger than in SU(2) nuclear matter. PACS:21.65.+f, 24.85.+p, 12.39Ba
Irreversibility, steady state, and nonequilibrium physics in relativistic heavy ion collisions
(1999)
Heavy ion collisions at ultrarelativistic energies offer the opportunity to study the irreversibility of multiparticle processes. Together with the many-body decays of resonances, the multiparticle processes cause the system to evolve according to Prigogine s steady states rather than towards statistical equilibrium. These results are general and can be easily checked by any microscopic string-, transport-, or cascade model for heavy ion collisions. The absence of pure equilibrium states sheds light on the di culties of thermal models in describing the yields and spectra of hadrons, especially mesons, in heavy ion collisions at bombarding energies above 10 GeV/nucleon. PACS numbers: 25.75.-q, 05.70.Ln, 24.10.Lx
Homogeneous nucleation of quark gluon plasma, finite size effects and longlived metastable objects
(1998)
The general formalism of homogeneous nucleation theory is applied to study the hadronization pattern of the ultra-relativistic quark-gluon plasma (QGP) undergoing a first order phase transition. A coalescence model is proposed to describe the evolution dynamics of hadronic clusters produced in the nucle- ation process. The size distribution of the nucleated clusters is important for the description of the plasma conversion. The model is most sensitive to the initial conditions of the QGP thermalization, time evolution of the energy den- sity, and the interfacial energy of the plasma hadronic matter interface. The rapidly expanding QGP is first supercooled by about T = T Tc = 4 6%. Then it reheats again up to the critical temperature Tc. Finally it breaks up into hadronic clusters and small droplets of plasma. This fast dynamics occurs within the first 5 10 fm/c. The finite size e ects and fluctuations near the critical temperature are studied. It is shown that a drop of longitudinally expanding QGP of the transverse radius below 4.5 fm can display a long-lived metastability. However, both in the rapid and in the delayed hadronization scenario, the bulk pion yield is emitted by sources as large as 3 4.5 fm. This may be detected experimentally both by a HBT interferometry signal and by the analysis of the rapidity distributions of particles in narrow pT -intervals at small |pT | on an event-by-event basis. PACS numbers: 12.38.Mh, 24.10.Pa, 25.75.-q, 64.60.Qb
We reexamine the scenario of homogeneous nucleation of the quark-gluon plasma produced in ultra-relativistic heavy ion collisions. A generalization of the standard nucleation theory to rapidly expanding system is proposed. The nucleation rate is derived via the new scaling parameter Z. It is shown that the size distribution of hadronic clusters plays an important role in the dynamics of the phase transition. The longitudinally expanding system is supercooled to about 3 6%, then it is reheated, and the hadronization is completed within 6 10 fm/c, i.e. 5 10 times faster than it was estimated earlier, in a strongly nonequilibrium way. PACS: 12.38.Mh; 12.39.Ba; 25.75.-q; 64.60.Qb
Layered {\alpha}-RuCl3 is a promising material to potentially realize the long-sought Kitaev quantum spin liquid with fractionalized excitations. While evidence of this exotic state has been reported under a modest in-plane magnetic field, such behavior is largely inconsistent with theoretical expectations of Kitaev phases emerging only in out-of-plane fields. These predicted field-induced states have been mostly out of reach due to the strong easy-plane anisotropy of bulk crystals, however. We use a combination of tunneling spectroscopy, magnetotransport, electron diffraction, and ab initio calculations to study the layer-dependent magnons, anisotropy, structure, and exchange coupling in atomically thin samples. Due to structural distortions, the sign of the average off-diagonal exchange changes in monolayer {\alpha}-RuCl3, leading to a reversal of magnetic anisotropy to easy-axis. Our work provides a new avenue to tune the magnetic interactions in {\alpha}-RuCl3 and allows theoretically predicted quantum spin liquid phases for out-of-plane fields to be more experimentally accessible.
The maximum recoverable strain of most crystalline solids is less than 1% because plastic deformation or fracture usually occurs at a small strain. In this work, we show that a SrNi2P2 micropillar exhibits pseudoelasticity with a large maximum recoverable strain of ~14% under uniaxial compression via unique reversible structural transformation, double lattice collapse-expansion that is repeatable under cyclic loading. Its high yield strength (~3.8±0.5 GPa) and large maximum recoverable strain bring out the ultrahigh modulus of resilience (~146±19MJ/m3) a few orders of magnitude higher than that of most engineering materials. The double lattice collapse-expansion mechanism shows stress-strain behaviors similar with that of conventional shape memory alloys, such as hysteresis and thermo-mechanical actuation, even though the structural changes involved are completely different. Our work suggests that the discovery of a new class of high performance ThCr2Si2-structured materials will open new research opportunities in the field of pseudoelasticity
We compute bremsstrahlung arising from the acceleration of individual charged baryons and mesons during the time evolution of high-energy Au+Au collisions at the Relativistic Heavy Ion Collider using a microscopic transport model. We elucidate the connection between bremsstrahlung and charge stop- ping by colliding artificial pure proton on pure neutron nuclei. From the inten- sity of low energy bremsstrahlung, the time scale and the degree of stopping could be accurately extracted without measuring any hadronic observables. PACS: 25.75.-q, 13.85.Qk
In this work, the phase diagram of the 2+1-dimensional Gross-Neveu model is investigated with baryon chemical potential as well as chiral chemical potential in the mean-field approximation. We study the theory using two lattice discretizations, which are both based on naive fermions. An inhomogeneous chiral phase is observed only for one of the two discretizations. Our results suggest that this phase disappears in the continuum limit.
In this work, inhomogeneous chiral phases are studied in a variety of Four-Fermion and Yukawa models in 2+1 dimensions at zero and non-zero temperature and chemical potentials. Employing the mean-field approximation, we do not find indications for an inhomogeneous phase in any of the studied models. We show that the homogeneous phases are stable against inhomogeneous perturbations. At zero temperature, full analytic results are presented.
The behavior of hadronic matter at high baryon densities is studied within Ultrarelativistic Quantum Molecular Dynamics (URQMD). Baryonic stopping is observed for Au+Au collisions from SIS up to SPS energies. The excitation function of flow shows strong sensitivities to the underlying equation of state (EOS), allowing for systematic studies of the EOS. Effects of a density dependent pole of the rho-meson propagator on dilepton spectra are studied for different systems and centralities at CERN energies.
Human feline leukaemia virus subgroup C receptor-related proteins 1 and 2 (FLVCR1 and 2) are major facilitator superfamily transporters from the solute carrier family 49. Dysregulation of these ubiquitous transporters has been linked to various haematological and neurological disorders. While both FLVCRs were initially proposed to hold a physiological function in heme transport, subsequent studies questioned this notion. Here, we used structural, computational and biochemical methods and conclude that these two FLVCRs function as human choline transporters. We present cryo-electron microscopy structures of FLVCRs in different inward- and outward-facing conformations, captured in the apo state or in complex with choline in their translocation pathways. Our findings provide insights into the molecular framework of choline coordination and transport, largely mediated by conserved cation-π interactions, and further illuminate the conformational dynamics of the transport cycle. Moreover, we identified a heme binding site on the protein surface of the FLVCR2 N-domain, and observed that heme actively drives the conformational transitions of the protein. This auxiliary binding site might indicate a potential regulatory role of heme in the FLVCR2 transport mechanisms. Our work resolves the contested substrate specificity of the FLVCRs, and sheds light on the process of maintaining cellular choline homeostasis at the molecular level.
We study the effects of isovector-scalar meson delta on the equation of state (EOS) of neutron star matter in strong magnetic fields. The EOS of neutron-star matter and nucleon effective masses are calculated in the framework of Lagrangian field theory, which is solved within the mean-field approximation. From the numerical results one can find that the delta-field leads to a remarkable splitting of proton and neutron effective masses. The strength of delta-field decreases with the increasing of the magnetic field and is little at ultrastrong field. The proton effective mass is highly influenced by magnetic fields, while the effect of magnetic fields on the neutron effective mass is negligible. The EOS turns out to be stiffer at B < 10^15G but becomes softer at stronger magnetic field after including the delta-field. The AMM terms can affect the system merely at ultrastrong magnetic field(B > 10^19G). In the range of 10^15 G - 10^18 G the properties of neutron-star matter are found to be similar with those without magnetic fields.
The amount of proton stopping in central Pb+Pb collisions from 20 160 A·GeV as well as hyperon and antihyperon rapidity distributions are calcu- lated within the UrQMD model in comparison to experimental data at 40, 80 and 160 A·GeV taken recently from the NA49 collaboration. Further- more, the amount of baryon stopping at 160 A·GeV for Pb + Pb collisions is studied as a function of centrality in comparison to the NA49 data. We find that the strange baryon yield is reasonably described for central colli- sions, however, the rapidity distributions are somewhat more narrow than the data. Moreover, the experimental antihyperon rapidity distributions at 40, 80 and 160 A·GeV are underestimated by up to factors of 3 - depending on the annihilation cross section employed - which might be addressed to missing multi-meson fusion channels in the UrQMD model. PACS 25.75.+r
We estimate the energy density epsilon pile-up at mid-rapidity in central Pb+Pb collisions from 2 200 GeV/nucleon. epsilon is decomposed into hadronic and partonic contributions. A detailed analysis of the collision dynamics in the framework of a microscopic transport model shows the importance of partonic degrees of freedom and rescattering of leading (di)quarks in the early phase of the reaction for Elab 30 GeV/nucleon. In Pb+Pb collisions at 160 GeV/nucleon the energy density reaches up to 4 GeV/fm3, 95% of which are contained in partonic degrees of freedom.
We study central collision of Pb + Pb at 20, 40, 80 and 160 A·GeV within the UrQMD transport approach and compare rapidity distributions of ,K+,K and with the recent measurements from the NA49 Collaboration at 40, 80 and 160 A·GeV. It is found that the UrQMD model reasonably describes the data, however, systematically overpredicts the yield by < 20%, whereas the K+ yield is underestimated by < 15%. The K yields are in a good agreement with the experimental data, the yields are also in a reasonable correspondence with the data for all energies. We find that hadronic flavour exchange reactions largely distort the information about the initial strangeness production mechanism at all energies considered. PACS: 25.75.+r
We calculate p, ±,K± and (+ 0) rapidity distributions and compare to experimental data from SIS to SPS energies within the UrQMD and HSD transport approaches that are both based on string, quark, diquark (q, ¯q, qq, ¯q ¯q) and hadronic degrees of freedom. The two transport models do not include any explicit phase transition to a quark-gluon plasma (QGP). It is found that both approaches agree rather well with each other and with the experimental rapidity distributions for protons, s, ± and K±. In- spite of this apparent agreement both transport models fail to reproduce the maximum in the excitation function for the ratio K+/ + found experimen- tally between 11 and 40 A·GeV. A comparison to the various experimental data shows that this failure is dominantly due to an insu cient description of pion rapidity distributions rather than missing strangeness . The modest di erences in the transport model results on the other hand can be attributed to di erent implementations of string formation and frag- mentation, that are not su ciently controlled by experimental data for the elementary reactions in vacuum.
The non-equilibrium quantum field dynamics is usually described in the closed-time-path formalism. The initial state correlations are introduced into the generating functional by non-local source terms. We propose a functional approach to the Dyson-Schwinger equation, which treats the non-local and local source terms in the same way. In this approach, the generating functional is formulated for the connected Green functions and one-particle-irreducible vertices. The great advantages of our approach over the widely used two-particle-irreducible method are that it is much simpler and that it is easy to implement the procedure in a computer program to automatically generate the Feynman diagrams for a given process. The method is then applied to a pure gluon plasma to derive the gauge-covariant transport equation from the Dyson-Schwinger equation in the background covariant gauge. We discuss the structure of the kinetic equation and show its relationship with the classical one. We derive the gauge-covariant collision part and present an approximation in the vicinity of equilibrium. The role of the non-local source kernel in the non-equilibrium system is discussed in the context of a free scalar field. PACS numbers: 12.38.Mh, 25.75.-q, 24.85.+p, 11.15.Kc
We derive the kinetic equation for pure gluon QCD plasma in a general way, applying the background field method. We show that the quantum kinetic equation contains a term as in the classical case, that describes a color charge precession of partons moving in the gauge field. We emphasize that this new term is necessary for the gauge covariance of the resulting equation.
We derive the quantum kinetic equation for a pure gluon plasma, applying the background field and closed-time-path method. The derivation is more general and transparent than earlier works. A term in the equation is found which, as in the classical case, corresponds to the color charge precession for partons moving in the gauge field. PACS numbers: 12.38.Mh, 25.75.-q, 24.85.+p, 11.15.Kc
By using the background field method of QCD in a path integral approach, we derive the equation of motion for the classical chromofield and for the gluon in a system containing the gluon and the classical chromofield simul- taneously. This inhomogeneous field equation contains a current term, which is the expectation value of a composite operator including linear, square and cubic terms of the gluon field. We also derive identities which the current should obey from the gauge invariance. We calculate the current at the leading order where the current induced by the gluon is opposite in sign to that induced by the quark. This is just the feature of the non-Abelian gauge field theory which has asymptotic freedom. Physically, the induced current can be treated as the displacement current in the polarized vacuum, and its e ect is equivalent to redefining the field and the coupling constant. PACS: 12.38.-t,12.38.Aw,11.15.-q,12.38.Mh
Abstract
The endoplasmic reticulum (ER) is a key organelle of membrane biogenesis and crucial for the folding of both membrane and secretory proteins. Sensors of the unfolded protein response (UPR) monitor the unfolded protein load in the ER and convey effector functions for maintaining ER homeostasis. Aberrant compositions of the ER membrane, referred to as lipid bilayer stress, are equally potent activators of the UPR. How the distinct signals from lipid bilayer stress and unfolded proteins are processed by the conserved UPR transducer Ire1 remains unknown. Here, we have generated a functional, cysteine-less variant of Ire1 and performed systematic cysteine crosslinking experiments in native membranes to establish its transmembrane architecture in signaling-active clusters. We show that the transmembrane helices of two neighboring Ire1 molecules adopt an X-shaped configuration independent of the primary cause for ER stress. This suggests that different forms of stress converge in a common, signaling-active transmembrane architecture of Ire1.
Summary
The endoplasmic reticulum (ER) is a hotspot of lipid biosynthesis and crucial for the folding of membrane and secretory proteins. The unfolded protein response (UPR) controls the size and folding capacity of the ER. The conserved UPR transducer Ire1 senses both unfolded proteins and aberrant lipid compositions to mount adaptive responses. Using a biochemical assay to study Ire1 in signaling-active clusters, Väth et al. provide evidence that the neighboring transmembrane helices of clustered Ire1 form an ‘X’ irrespectively of the primary cause of ER stress. Hence, different forms of ER stress converge in a common, signaling-active transmembrane architecture of Ire1.
The regeneration of hadronic resonances is discussed for heavy ion collisions at SPS and SIS-300 energies. The time evolutions of Delta, rho and phi resonances are investigated. Special emphasize is put on resonance regeneration after chemical freeze-out. The emission time spectra of experimentally detectable resonances are explored.
We predict transverse and longitudinal momentum spectra and yields of rho 0 and omega mesons reconstructed from hadron correlations in C+C reactions at 2~AGeV. The rapidity and pT distributions for reconstructable rho 0 mesons differs strongly from the primary distribution, while the omega's distributions are only weakly modified. We discuss the temporal and spatial distributions of the particles emitted in the hadron channel. Finally, we report on the mass shift of the rho 0 due to its coupling to the N*(1520), which is observable in both the di-lepton and pi pi channel. Our calculations can be tested with the Hades experiment at GSI, Darmstadt.
Lattice strains of appropriate symmetry have served as an excellent tool to explore the interaction of superconductivity in the iron-based superconductors with nematic and stripe spin-density wave (SSDW) order, which are both closely tied to an orthorhombic distortion. In this work, we contribute to a broader understanding of the coupling of strain to superconductivity and competing normal-state orders by studying CaKFe4As4 under large, in-plane strains of B1g and B2g symmetry. In contrast to the majority of iron-based superconductors, pure CaKFe4As4 exhibits superconductivity with relatively high transition temperature of Tc∼35 K in proximity of a non-collinear, tetragonal, hedgehog spin-vortex crystal (SVC) order. Through experiments, we demonstrate an anisotropic in-plane strain response of Tc, which is reminiscent of the behavior of other pnictides with nematicity. However, our calculations suggest that in CaKFe4As4, this anisotropic response correlates with the one of the SVC fluctuations, highlighting the close interrelation of magnetism and high-Tc superconductivity. By suggesting moderate B2g strains as an effective parameter to change the stability of SVC and SSDW, we outline a pathway to a unified phase diagram of iron-based superconductivity.
Motivated by the wealth of proposals and realizations of nontrivial topological phases in EuCd2As2, such as a Weyl semimetallic state and the recently discussed semimetallic versus semiconductor behavior in this system, we analyze in this work the role of the delicate interplay of Eu magnetism, strain and pressure on the realization of such phases. For that we invoke a combination of a group theoretical analysis with ab initio density functional theory calculations and uncover a rich phase diagram with various non-trivial topological phases beyond a Weyl semimetallic state, such as axion and topological crystalline insulating phases, and discuss their realization.
Motivated by the wealth of proposals and realizations of nontrivial topological phases in EuCd2As2, such as a Weyl semimetallic state and the recently discussed semimetallic versus semiconductor behavior in this system, we analyze in this work the role of the delicate interplay of Eu magnetism, strain and pressure on the realization of such phases. For that we invoke a combination of a group theoretical analysis with ab initio density functional theory calculations and uncover a rich phase diagram with various non-trivial topological phases beyond a Weyl semimetallic state, such as axion and topological crystalline insulating phases, and discuss their realization.
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is required for cell entry and is the major focus for vaccine development. We combine cryo electron tomography, subtomogram averaging and molecular dynamics simulations to structurally analyze S in situ. Compared to recombinant S, the viral S is more heavily glycosylated and occurs predominantly in a closed pre-fusion conformation. We show that the stalk domain of S contains three hinges that give the globular domain unexpected orientational freedom. We propose that the hinges allow S to scan the host cell surface, shielded from antibodies by an extensive glycan coat. The structure of native S contributes to our understanding of SARS-CoV-2 infection and the development of safe vaccines. The large scale tomography data set of SARS-CoV-2 used for this study is therefore sufficient to resolve structural features to below 5 Ångstrom, and is publicly available at EMPIAR-10453.
Cryo-electron tomography (cryo-ET) is a powerful method to elucidate subcellular architecture and to structurally analyse biomolecules in situ by subtomogram averaging (STA). Specimen thickness is a key factor affecting cryo-ET data quality. Cells that are too thick for transmission imaging can be thinned by cryo-focused-ion-beam (cryo-FIB) milling. However, optimal specimen thickness for cryo-ET on lamellae has not been systematically investigated. Furthermore, the ions used to ablate material can cause damage in the lamellae, thereby reducing STA resolution. Here, we systematically benchmark the resolution depending on lamella thickness and the depth of the particles within the sample. Up to ca. 180 nm, lamella thickness does not negatively impact resolution. This shows that there is no need to generate very thin lamellae and thickness can be chosen such that it captures major cellular features. Furthermore, we show that gallium-ion-induced damage extends to depths of up to 30 nm from either lamella surface.
Changes in the efficacies of synapses are thought to be the neurobiological basis of learning and memory. The efficacy of a synapse depends on its current number of neurotransmitter receptors. Recent experiments have shown that these receptors are highly dynamic, moving back and forth between synapses on time scales of seconds and minutes. This suggests spontaneous fluctuations in synaptic efficacies and a competition of nearby synapses for available receptors. Here we propose a mathematical model of this competition of synapses for neurotransmitter receptors from a local dendritic pool. Using minimal assumptions, the model produces a fast multiplicative scaling behavior of synapses. Furthermore, the model explains a transient form of heterosynaptic plasticity and predicts that its amount is inversely related to the size of the local receptor pool. Overall, our model reveals logistical tradeoffs during the induction of synaptic plasticity due to the rapid exchange of neurotransmitter receptors between synapses.
Post-merger gravitational-wave signal from neutron-star binaries: a new look at an old problem
(2023)
The spectral properties of the post-merger gravitational-wave signal from a binary of neutron stars encodes a variety of information about the features of the system and of the equation of state describing matter around and above nuclear saturation density. Characterising the properties of such a signal is an “old” problem, which first emerged when a number of frequencies were shown to be related to the properties of the binary through “quasi-universal” relations. Here we take a new look at this old problem by computing the properties of the signal in terms of the Weyl scalar ψ4. In this way, and using a database of more than 100 simulations, we provide the first evidence for a new instantaneous frequency, f ψ4 0, associated with the instant of quasi timesymmetry in the postmerger dynamics, and which also follows a quasi-universal relation. We also derive a new quasi-universal relation for the merger frequency f h mer, which provides a description of the data that is four times more accurate than previous expressions while requiring fewer fitting coefficients. Finally, consistently with the findings of numerous studies before ours, and using an enlarged ensamble of binary systems we point out that the ℓ = 2, m = 1 gravitational-wave mode could become comparable with the traditional ℓ = 2, m = 2 mode on sufficiently long timescales, with strain amplitudes in a ratio |h 21|/|h 22| ∼ 0.1 − 1 under generic orientations of the binary, which could be measured by present detectors for signals with large signal-to-noise ratio or by third-generation detectors for generic signals should no collapse occur.
Using full 3+1 dimensional general-relativistic hydrodynamic simulations of equal- and unequal-mass neutron-star binaries with properties that are consistent with those inferred from the inspiral of GW170817, we perform a detailed study of the quark-formation processes that could take place after merger. We use three equations of state consistent with current pulsar observations derived from a novel finite-temperature framework based on V-QCD, a non-perturbative gauge/gravity model for Quantum Chromodynamics. In this way, we identify three different post-merger stages at which mixed baryonic and quark matter, as well as pure quark matter, are generated. A phase transition triggered collapse already ≲10ms after the merger reveals that the softest version of our equations of state is actually inconsistent with the expected second-long post-merger lifetime of GW170817. Our results underline the impact that multi-messenger observations of binary neutron-star mergers can have in constraining the equation of state of nuclear matter, especially in its most extreme regimes.
We have calculated the D-meson spectral density at finite temperature within a self-consistent coupled-channel approach that generates dynamically the Lambda_c (2593) resonance. We find a small mass shift for the D-meson in this hot and dense medium while the spectral density develops a sizeable width. The reduced attraction felt by the D-meson in hot and dense matter together with the large width observed have important consequences for the D-meson production in the future CBM experiment at FAIR.
We obtain the D-meson spectral density at finite temperature for the conditions of density and temperature expected at FAIR. We perform a self-consistent coupled-channel calculation taking, as a bare interaction, a separable potential model. The Lambda_c (2593) resonance is generated dynamically. We observe that the D-meson spectral density develops a sizeable width while the quasiparticle peak stays close to the free position. The consequences for the D-meson production at FAIR are discussed.
The D-meson spectral density at finite temperature is obtained within a self-consistent coupled-channel approach. For the bare meson-baryon interaction, a separable potential is taken, whose parameters are fixed by the position and width of the Lambda_c (2593) resonance. The quasiparticle peak stays close to the free D-meson mass, indicating a small change in the effective mass for finite density and temperature. However, the considerable width of the spectral density implies physics beyond the quasiparticle approach. Our results indicate that the medium modifications for the D-mesons in nucleus-nucleus collisions at FAIR (GSI) will be dominantly on the width and not, as previously expected, on the mass.
To be published in J. Phys. G - Proceedings of SQM 2004 : We review the results from the various hydrodynamical and transport models on the collective flow observables from AGS to RHIC energies. A critical discussion of the present status of the CERN experiments on hadron collective flow is given. We emphasize the importance of the flow excitation function from 1 to 50 A.GeV: here the hydrodynamic model has predicted the collapse of the v2-flow ~ 10 A.GeV; at 40 A.GeV it has been recently observed by the NA49 collaboration. Since hadronic rescattering models predict much larger flow than observed at this energy we interpret this observation as evidence for a first order phase transition at high baryon density r b. Moreover, the connection of the elliptic flow v2 to jet suppression is examined. It is proven experimentally that the collective flow is not faked by minijet fragmentation. Additionally, detailed transport studies show that the away-side jet suppression can only partially (< 50%) be due to hadronic rescattering. Furthermore, the change in sign of v1, v2 closer to beam rapidity is related to the occurence of a high density first order phase transition in the RHIC data at 62.5, 130 and 200 A.GeV.
Results from various theoretical approaches and ideas presented at this exciting meeting (summary talk at the 5th International Conference on Physics and Astrophysics of Quark Gluon Plasma (ICPAQGP - 2005)) are reviewed. I also point towards future directions, in particular hydrodynamic behaviour induced by jets traveling through the quark-gluon plasma, which might be worth looking at in more detail.
The experimental signatures of TeV-mass black hole (BH) formation in heavy ion collisions at the LHC is examined. We find that the black hole production results in a complete disappearance of all very high p_T (> 500 GeV) back-to-back correlated di-jets of total mass M > M_f ~ 1 TeV. We show that the subsequent Hawking-decay produces multiple hard mono-jets and discuss their detection. We study the possibility of cold black hole remnant (BHR) formation of mass ~ M_f and the experimental distinguishability of scenarios with BHRs and those with complete black hole decay. Due to the rather moderate luminosity in the first year of LHC running the least chance for the observation of BHs or BHRs at this early stage will be by ionizing tracks in the ALICE TPC. Finally we point out that stable BHRs would be interesting candidates for energy production by conversion of mass to Hawking radiation.
The production of Large Extra Dimension (LXD) Black Holes (BHs), with a new, fundamental mass scale of M_f = 1 TeV, has been predicted to occur at the Large Hadron Collider, LHC, with the formidable rate of 10^8 per year in p-p collisions at full energy, 14 TeV, and at full luminosity. We show that such LXD-BH formation will be experimentally observable at the LHC by the complete disappearance of all very high p_t (> 500 GeV) back-to-back correlated Di-Jets of total mass M > M_f = 1 TeV. We suggest to complement this clear cut-off signal at M > 2*500 GeV in the di-jet-correlation function by detecting the subsequent, Hawking-decay products of the LXD-BHs, namely either multiple high energy (> 100 GeV) SM Mono-Jets (i.e. away-side jet missing), sprayed off the evaporating BHs isentropically into all directions or the thermalization of the multiple overlapping Hawking-radiation in a eckler-Kapusta-Plasma. Microcanonical quantum statistical calculations of the Hawking evaporation process for these LXD-BHs show that cold black hole remnants (BHRs) of Mass sim M_f remain leftover as the ashes of these spectacular Di-Jet-suppressed events. Strong Di-Jet suppression is also expected with Heavy Ion beams at the LHC, due to Quark-Gluon-Plasma induced jet attenuation at medium to low jet energies, p_t < 200 GeV. The (Mono-)Jets in these events can be used to trigger for Tsunami-emission of secondary compressed QCD-matter at well defined Mach-angles, both at the trigger side and at the awayside (missing) jet. The Machshock-angles allow for a direct measurement of both the equation of state EoS and the speed of sound c_s via supersonic bang in the "big bang" matter. We discuss the importance of the underlying strong collective flow - the gluon storm - of the QCD- matter for the formation and evolution of these Machshock cones. We predict a significant deformation of Mach shocks from the gluon storm in central Au+Au collisions at RHIC and LHC energies, as compared to the case of weakly coupled jets propagating through a static medium. A possible complete stopping of pt > 50 GeV jets at the LHC in 2-3 fm yields nonlinear high density Mach shocks in he quark gluon plasma, which can be studied in the complex emission and disintegration pattern of the possibly supercooled matter. We report on first full 3-dimensional fluid dynamical studies of the strong effects of a first order phase transition on the evolution and the Tsunami-like Mach shock emission of the QCD matter.
A critical discussion of the present status of the CERN experiments on charm dynamics and hadron collective flow is given. We emphasize the importance of the flow excitation function from 1 to 50 A·GeV: here the hydrodynamic model has predicted the collapse of the v1-flow and of the v2-flow at 10 A·GeV; at 40 A·GeV it has been recently observed by the NA49 collaboration. Since hadronic rescattering models predict much larger flow than observed at this energy we interpret this observation as potential evidence for a first order phase transition at high baryon density B. A detailed discussion of the collective flow as a barometer for the equation of state (EoS) of hot dense matter at RHIC follows. Here, hadronic rescattering models can explain < 30% of the observed elliptic flow, v2, for pT > 2 GeV/c. This is interpreted as evidence for the production of superdense matter at RHIC with initial pressure far above hadronic pressure, p > 1 GeV/fm3. We suggest that the fluctuations in the flow, v1 and v2, should be measured in future since ideal hydrodynamics predicts that they are larger than 50 % due to initial state fluctuations. Furthermore, the QGP coe cient of viscosity may be determined experimentally from the fluctuations observed. The connection of v2 to jet suppression is examined. It is proven experimentally that the collective flow is not faked by minijet fragmentation. Additionally, detailed transport studies show that the awayside jet suppression can only partially (< 50%) be due to hadronic rescattering. We, finally, propose upgrades and second generation experiments at RHIC which inspect the first order phase transition in the fragmentation region, i.e. at µB 400 MeV (y 4 5), where the collapse of the proton flow should be seen in analogy to the 40 A·GeV data. The study of Jet-Wake-riding potentials and Bow shocks caused by jets in the QGP formed at RHIC can give further information on the equation of state (EoS) and transport coe cients of the Quark Gluon Plasma (QGP).
Strangeness enhancement is discussed as a feature specific to relativistic nuclear collisions which create a fireball of strongly interacting matter at high energy density. At very high energy this is suggested to be partonic matter, but at lower energy it should consist of yet unknown hadronic degrees of freedom. The freeze-out of this high density state to a hadron gas can tell us about properties of fireball matter. The hadron gas at the instant of its formation captures conditions directly at the QCD phase boundary at top SPS and RHIC energy, chiefly the critical temperature and energy density.
A steep maximum occurs in the Wroblewski ratio between strange and non-strange quarks created in central nucleus-nucleus collisions, of about A=200, at the lower SPS energy square root s approximately equal to 7 GeV. By analyzing hadronic multiplicities within the grand canonical statistical hadronization model this maximum is shown to occur at a baryochemical potential of about 450 MeV. In comparison, recent QCD lattice calculations at finite baryochemical potential suggest a steep maximum of the light quark susceptibility, to occur at similar mu B, indicative of "critical fluctuation" expected to occur at or near the QCD critical endpoint. This endpoint hat not been firmly pinned down but should occur in the 300 MeV < mu c B < 700 MeV interval. It is argued that central collisions within the low SPS energy range should exhibit a turning point between compression/heating, and expansion/cooling at energy density, temperature and mu B close to the suspected critical point. Whereas from top SPS to RHIC energy the primordial dynamics create a turning point far above in epsilon and T, and far below in mu B. And at lower AGS energies the dynamical trajectory stays below the phase boundary. Thus, the observed sharp strangeness maximum might coincide with the critical square root s at which the dynamics settles at, or near the QCD endpoint.
A selection of recent data referring to Pb+Pb collisions at the SPS CERN energy of 158 GeV per nucleon is presented which might describe the state of highly excited strongly interacting matter both above and below the deconfinement to hadronization (phase) transition predicted by lattice QCD. A tentative picture emerges in which a partonic state is indeed formed in central Pb+Pb collisions which hadronizes at about T = 185 MeV, and expands its volume more than tenfold, cooling to about 120 MeV before hadronic collisions cease. We suggest further that all SPS collisions, from central S+S onward, reach that partonic phase, the maximum energy density increasing with more massive collision systems.
Hadronic yields and yield ratios observed in Pb+Pb collisions at the SPS energy of 158 GeV per nucleon are known to resemble a thermal equilibrium population at T=180 +/- 10 MeV, also observed in elementary e+ + e- to hadron data at LEP. We argue that this is the universal consequence of the QCD parton to hadron phase transition populating the maximum entropy state. This state is shown to survive the hadronic rescattering and expansion phase, freezing in right after hadronization due to the very rapid longitudinal and transverse expansion that is inferred from Bose-Einstein pion correlation analysis of central Pb+Pb collisions.
With new data available from the SPS, at 40 and 80 GeV/A, I review the systematics of bulk hadron multiplicities, with prime focus on strangeness production. The classical concept of strangeness enhancement in central AA collisions is reviewed, in view of the statistical hadronization model which suggests to understand strangeness enhancement to arise chiefly in the transition from the canonical to the grand canonical version of that model. I. e. enhancement results from the fading away of canonical suppression. The model also captures the striking strangeness maximum observed in the vicinity of sqrt s approx 8 GeV. A puzzle remains in the understanding of apparent grand canonical order at the lower SPS, and at AGS energies.
Relativistic nucleus-nucleus collisions create a "fireball" of strongly interacting matter at high energy density. At very high energy this is suggested to be partonic matter, but at lower energy it should consist of yet unknown hadronic, perhaps coherent degrees of freedom. The freeze-out of this high density state to a hadron gas can tell us about properties of fireball matter. Date (v1): Thu, 19 Dec 2002 12:52:34 GMT (146kb) Date (revised v2): Thu, 16 Jan 2003 15:11:47 GMT (146kb) Date (revised v3): Wed, 14 May 2003 12:49:35 GMT (146kb)
Dissociation rates of J / psi's with comoving mesons : thermal versus nonequilibrium scenario.
(1998)
We study J/psi dissociation processes in hadronic environments. The validity of a thermal meson gas ansatz is tested by confronting it with an alternative, nonequilibrium scenario. Heavy ion collisions are simulated in the frame- work of the microscopic transport model UrQMD, taking into account the production of charmonium states through hard parton-parton interactions and subsequent rescattering with hadrons. The thermal gas and microscopic transport scenarios are shown to be very dissimilar. Estimates of J/psi survival probabilities based on thermal models of comover interactions in heavy ion collisions are therefore not reliable.
Charmonium production and absorption in heavy ion collisions is studied with the Ultrarelativisitic Quantum Molecular Dynamics model. We compare the scenario of universal and time independent color-octet dissociation cross sections with one of distinct color-singlet J/psi, psi 2 and CHIc states, evolving from small, color transparent configurations to their asymptotic sizes. The measured J/psi production cross sections in pA and AB collisions at SPS energies are consistent with both purely hadronic scenarios. The predicted rapidity dependence of J/psi suppression can be used to discriminate between the two experimentally. The importance of interactions with secondary hadrons and the applicability of thermal reaction kinetics to J/psi absorption are in- vestigated. We discuss the e ect of nuclear stopping and the role of leading hadrons. The dependence of the 2/J/psi ratio on the model assumptions and the possible influence of refeeding processes is also studied.
We study J/psi suppression in AB collisions assuming that the charmonium states evolve from small, color transparent configurations. Their interaction with nucleons and nonequilibrated, secondary hadrons is simulated us- ing the microscopic model UrQMD. The Drell-Yan lepton pair yield and the J/psi /Drell-Yan ratio are calculated as a function of the neutral transverse en- ergy in Pb+Pb collisions at 160 GeV and found to be in reasonable agreement with existing data.
Measured hadron yields from relativistic nuclear collisions can be equally well understood in two physically distinct models, namely a static thermal hadronic source vs. a time-dependent, nonequilibrium hadronization o a quark-gluon plasma droplet. Due to the time-dependent particle evapora- tion o the hadronic surface in the latter approach the hadron ratios change (by factors of <H 5) in time. Final particle yields reflect time averages over the actual thermodynamic properties of the system at a certain stage of the evolution. Calculated hadron, strangelet and (anti-)cluster yields as well as freeze-out times are presented for di erent systems. Due to strangeness distillation the system moves rapidly out of the T, µq plane into the µs-sector. Classif.: 25.75.Dw, 12.38.Mh, 24.85.+p
The deconfinement transition region between hadronic matter and quark-gluon plasma is studied for finite volumes. Assuming simple model equations of state and a first order phase transition, we find that fluctuations in finite volumes hinder a sharp separation between the two phases around the critical temperature, leading to a rounding of the phase transition. For reaction volumes expected in heavy ion experiments, the softening of the equation of state is reduced considerably. This is especially true when the requirement of exact color-singletness is included in the QGP equation of state.
We present a RQMD calculation of antiproton yields and their momentum distribution in Ne + NaF collisions at 2 GeV/u. The antiprotons can be produced below threshold due to multi-step excitations for which meson-baryon interactions play a considerable role. In this system the annihilation probability for an initially produced antiproton is predicted to be about 65%.
We calculate the evolution of quark-gluon-plasma droplets during the hadronization in a thermodynamical model. It is speculated that cooling as well as strangeness enrichment allow for the formation of strangelets even at very high initial entropy per baryon S/Ainit H 500 and low initial baryon numbers of Ainit B H 30. It is shown that the droplet with vanishing initial chemical potential of strange quarks and a very moderate chemical potential of up/down quarks immediately charges up with strangeness. Baryon densi- ties of H 2 0 and strange chemical potentials of µs > 350 MeV are reached if strangelets are stable. The importance of net baryon and net strangeness fluctuations for the possible strangelet formation at RHIC and LHC is em- phasized. Pacs-Classif.: 25.15.tr, 12.38.Mh, 24.85.tp
A study of secondary Drell-Yan production in nuclear collisions is presented for SPS energies. In addition to the lepton pairs produced in the initial collisions of the projectile and target nucleons, we consider the potentially high dilepton yield from hard valence antiquarks in produced mesons and antibaryons. We calculate the secondary Drell-Yan contributions taking the collision spectrum of hadrons from the microscopic model URQMD. The con- tributions from meson-baryon interactions, small in hadron-nucleus interac- tions, are found to be substantial in nucleus-nucleus collisions at low dilepton masses. Preresonance collisions of partons may further increase the yields.
We study the thermodynamic properties of infinite nuclear matter with the Ultrarelativistic Quantum Molecular Dynamics (URQMD), a semiclassical transport model, running in a box with periodic boundary conditions. It appears that the energy density rises faster than T4 at high temperatures of T approx. 200 - 300 MeV. This indicates an increase in the number of degrees of freedom. Moreover, We have calculated direct photon production in Pb+Pb collisions at 160 GeV/u within this model. The direct photon slope from the microscopic calculation equals that from a hydrodynamical calculation without a phase transition in the equation of state of the photon source.
In the framework of RQMD we investigate antiproton observables in massive heavy ion collisions at AGS energies and compare to preliminary results of the E878 collaboration. We focus here on the considerable influence of the real part of an antinucleon nucleus optical potential on the ¯p momentum spectra. Pacs-numbers: 14.20 Dh, 25.70.-z
We want to draw the attention to the dynamics of a (finite) hadronizing quark matter drop. Strange and antistrange quarks do not hadronize at the same time for a baryon-rich system1. Both the hadronic and the quark matter phases enter the strange sector fs 6= 0 of the phase diagram almost immediately, which has up to now been neglected in almost all calculations of the time evolution of the system. Therefore it seems questionable, whether final particle yields reflect the actual thermodynamic properties of the system at a certain stage of the evolution. We put special interest on the possible formation of exotic states, namely strangelets (multistrange quark clusters). They may exist as (meta-)stable exotic isomers of nuclear matter 2. It was speculated that strange matter might exist also as metastable exotic multi-strange (baryonic) objects (MEMO s 3). The possible creation in heavy ion collisions of long-lived remnants of the quark-gluon-plasma, cooled and charged up with strangeness by the emission of pions and kaons, was proposed in 1,4,5. Strangelets can serve as signatures for the creation of a quark gluon plasma. Currently, both at the BNL-AGS and at the CERN-SPS experiments are carried out to search for MEMO s and strangelets, e. g. by the E864, E878 and the NA52 collaborations9,
Under temperature or pressure tuning, tetragonal EuPd2Si2 is known to undergo a valence transition from nearly divalent to nearly trivalent Eu accompanied by a volume reduction. Albeit intensive work, its microscopic origin is still being discussed. Here, we investigate the mechanism of the valence transition under volume compression by ab initio density functional theory (DFT) calculations. Our analysis of the electronic and magnetic properties of EuPd2Si2 when approaching the valence transition shows an enhanced c-f hybridization between localized Eu 4f states and itinerant conduction states (Eu 5d, Pd 4d, and Si 3p) where an electronic charge redistribution takes place. We observe that the change in the electronic structure is intimately related to the volume reduction where Eu-Pd(Si) bond lengths shorten and, for the transition to happen, we trace the delicate balance between electronic bandwidth, crystal field splitting, Coulomb repulsion, Hund's coupling and spin-orbit coupling. In a next step we compare and benchmark our DFT results to surface-sensitive photoemission data in which the mixed-valent properties of EuPd2Si2 are reflected in a simultaneous observation of divalent and trivalent signals from the Eu 4f shell. The study serves as well to explore the limits of density functional theory and the choice of exchange correlation functionals to describe such a phenomenon as a valence transition.
Under temperature or pressure tuning, tetragonal EuPd2Si2 is known to undergo a valence transition from nearly divalent to nearly trivalent Eu accompanied by a volume reduction. Albeit intensive work, its origin is not yet completely understood. Here, we investigate the mechanism of the valence transition under volume compression by density functional theory calculations (DFT). Our analysis suggests that the transition is a consequence of an enhanced c−f hybridization between localized Eu 4f states and itinerant conduction states (Eu 5d, Pd 4d, and Si 3p) where the interplay of the electronic bandwidth, crystal field environment, Coulomb repulsion, Hund's coupling and spin-orbit coupling plays a crucial role for the transition to happen. The change in the electronic structure is intimately related to the volume reduction where Eu-Pd(Si) bond lengths shorten. In a next step we compare our DFT results to surface-sensitive photoemission data in which the mixed-valent properties of EuPd2Si2 are reflected in a simultaneous observation of divalent and trivalent signals from the Eu 4f shell.
Although iron-based catalysts are regarded as a promising alternative to precious metal catalysts, their precise electronic structures during catalysis still pose challenges for computational descriptions. A particularly urgent question is the influence of the environment on the electronic structure, and how to describe this properly with computational methods. Here, we study an iron porphyrin chloride complex adsorbed on a graphene sheet using density functional theory calculations to detail how much the electronic structure is influenced by the presence of a graphene layer. Our results indicate that weak interactions due to van der Waals forces dominate between the porphyrin complex and graphene, and only a small amount of charge is transferred between the two entities. Furthermore, the interplay of the ligand field environment, strong p − d hybridization, and correlation effects within the complex are strongly involved in determining the spin state of the iron ion. By bridging molecular chemistry and solid state physics, this study provides first steps towards a joint analysis of the properties of iron-based catalysts from first principles.
The discovery of the 1144-phase, e.g. CaKFe4As4, creates opportunities to build novel intermetallics with alternative stacking of two parent compounds. Here we formalize the idea by defining a class of bulk crystalline solids with A-B stacking (including 1144-phases and beyond), which is a generalization of hetero-structures from few-layer or thin-film semi-conductors to bulk intermetallics. Theoretically, four families of phosphides \textit{AB}(TM)4P4 (TM=Fe, Ru, Co, Ni) are investigated by first-principles calculations, wherein configurational, vibrational and electronic degrees of freedom are considered. It predicts a variety of stable 1144-phases (especially Ru- and Fe-phosphides). Stability rules are found and structural/electronic properties are discussed. Experimentally, we synthesize high-purity CaKRu4P4 as a proof of principle example. The synthetic method is simple and easily applied. Moreover, it alludes to a strategy to explore complex multi-component compounds, facilitated by a phase diagram coordinated by collective descriptors.
The discovery of the 1144-phase, e.g. CaKFe4As4, creates opportunities to build novel intermetallics with alternative stacking of two parent compounds. Here we formalize the idea by defining a class of bulk crystalline solids with A-B stacking (including 1144-phases and beyond), which is a generalization of hetero-structures from few-layer or thin-film semi-conductors to bulk intermetallics. Theoretically, four families of phosphides \textit{AB}(TM)4P4 (TM=Fe, Ru, Co, Ni) are investigated by first-principles calculations, wherein configurational, vibrational and electronic degrees of freedom are considered. It predicts a variety of stable 1144-phases (especially Ru- and Fe-phosphides). Stability rules are found and structural/electronic properties are discussed. Experimentally, we synthesize high-purity CaKRu4P4 as a proof of principle example. The synthetic method is simple and easily applied. Moreover, it alludes to a strategy to explore complex multi-component compounds, facilitated by a phase diagram coordinated by collective descriptors.
The discovery of the 1144-phase, e.g. CaKFe4As4, creates opportunities to build novel intermetallics with alternative stacking of two parent compounds. Here we formalize the idea and introduce a concept, namely hetero-crystals (HC), to describe a unique class of bulk crystalline solids with such A-B stacking (including 1144-phases and beyond). HC generalizes hetero-structures from few-layer or thin-film semi-conductors to bulk intermetallics. We illustrate the HC concept with the example of 1144-phases. Theoretically, four families of phosphides \textit{AB}(TM)4P4 (TM=Fe, Ru, Co, Ni) are investigated by first-principles calculations, wherein configurational, vibrational and electronic degrees of freedom are considered. It predicts a variety of stable 1144-phases (especially Ru- and Fe-phosphides). Stability rules are found and structural/electronic properties are discussed. Experimentally, we synthesize high-purity CaKRu4P4 as a proof of principle example of such a HC. The synthetic method is simple and can be applied to other HC. Moreover, HC alludes to a new strategy to explore complex multi-component compounds, facilitated by a new phase diagram coordinated by collective descriptors.
The yields of strange particles are calculated with the UrQMD model for p,Pb(158 AGeV)Pb collisions and compared to experimental data. The yields are enhanced in central collisions if compared to proton induced or peripheral Pb+Pb collisions. The enhancement is due to secondary interactions. Nevertheless, only a reduction of the quark masses or equivalently an increase of the string tension provides an adequate description of the large observed enhancement factors (WA97 and NA49). Furthermore, the yields of unstable strange resonances as the Lambda star(1520) resonance or the phi meson are considerably affected by hadronic rescattering of the decay products.
We investigate the effects of strong color fields and of the associated enhanced intrinsic transverse momenta on the phi-meson production in ultrarelativistic heavy ion collisions at RHIC. The observed consequences include a change of the spectral slopes, varying particle ratios, and also modified mean transverse momenta. In particular, the composition of the production processes of phi-mesons, that is, direct production vs. coalescence-like production, depends strongly on the strength of the color fields and intrinsic transverse momenta and thus represents a sensitive probe for their measurement.
The disappearance of flow
(1995)
We investigate the disappearance of collective flow in the reaction plane in heavy-ion collisions within a microscopic model (QMD). A systematic study of the impact parameter dependence is performed for the system Ca+Ca. The balance energy strongly increases with impact parameter. Momentum dependent interactions reduce the balance energies for intermediate impact parameters b ~ 4.5 fm. Dynamical negative flow is not visible in the laboratory frame but does exist in the contact frame for the heavy system Au+Au. For semi-peripheral collisions of Ca+Ca with b ~ 6.5 fm a new two-component flow is discussed. Azimuthal distributions exhibit strong collectiv flow signals, even at the balance energy.
We make predictions for the kaon interferometry measurements in Au+Au collisions at the Relativistic Heavy Ion Collider (RHIC). A first order phase transition from a thermalized Quark-Gluon-Plasma (QGP) to a gas of hadrons is assumed for the transport calculations. The fraction of kaons that are directly emitted from the phase boundary is considerably enhanced at large transverse momenta K T ~ 1 GeV/c. In this kinematic region, the sensitivity of the R out/R side ratio to the QGP-properties is enlarged. Here, the results of the 1-dimensional correlation analysis are presented. The extracted interferometry radii, depending on K-Theta, are not unusually large and are strongly affected by momentum resolution effects.
We present calculations of two-pion and two-kaon correlation functions in relativistic heavy ion collisions from a relativistic transport model that includes explicitly a first-order phase transition from a thermalized quark-gluon plasma to a hadron gas. We compare the obtained correlation radii with recent data from RHIC. The predicted R_side radii agree with data while the R_out and R_long radii are overestimated. We also address the impact of in-medium modifications, for example, a broadening of the rho-meson, on the correlation radii. In particular, the longitudinal correlation radius R_long is reduced, improving the comparison to data.
We calculate the Gaussian radius parameters of the pion-emitting source in high energy heavy ion collisions, assuming a first order phase transition from a thermalized Quark-Gluon-Plasma (QGP) to a gas of hadrons. Such a model leads to a very long-lived dissipative hadronic rescattering phase which dominates the properties of the two-pion correlation functions. The radii are found to depend only weakly on the thermalization time tau i, the critical temperature T c (and thus the latent heat), and the specific entropy of the QGP. The dissipative hadronic stage enforces large variations of the pion emission times around the mean. Therefore, the model calculations suggest a rapid increase of R out/R side as a function of K T if a thermalized QGP were formed.
Directed and elliptic flow
(1999)
We compare microscopic transport model calculations to recent data on the directed and elliptic flow of various hadrons in 2 - 10 A GeV Au+Au and Pb (158 A GeV) Pb collisions. For the Au+Au excitation function a transition from the squeeze-out to an in-plane enhanced emission is consistently described with mean field potentials corresponding to one incompressibility. For the Pb (158 A GeV) Pb system the elliptic flow prefers in-plane emission both for protons and pions, the directed flow of protons is opposite to that of the pions, which exhibit anti-flow. Strong directed transverse flow is present for protons and Lambdas in Au (6 A GeV) Au collisions as well. Both for the SPS and the AGS energies the agreement between data and calculations is remarkable.
The centrality dependence of (multi-)strange hadron abundances is studied for Pb(158 AGeV)Pb reactions and compared to p(158 GeV)Pb collisions. The microscopic transport model UrQMD is used for this analysis. The predicted Lambda/pi-, Xi-/pi- and Omega-/pi- ratios are enhanced due to rescattering in central Pb-Pb collisions as compared to peripheral Pb-Pb or p-Pb collisions. A reduction of the constituent quark masses to the current quark masses m_s \sim 230 MeV, m_q \sim 10 MeV, as motivated by chiral symmetry restoration, enhances the hyperon yields to the experimentally observed high values. Similar results are obtained by an ad hoc overall increase of the color electric field strength (effective string tension of kappa=3 GeV/fm). The enhancement depends strongly on the kinematical cuts. The maximum enhancement is predicted around midrapidity. For Lambda's, strangeness suppression is predicted at projectile/target rapidity. For Omega's, the predicted enhancement can be as large as one order of magnitude. Comparisons of Pb-Pb data to proton induced asymmetric (p-A) collisions are hampered due to the predicted strong asymmetry in the various rapidity distributions of the different (strange) particle species. In p-Pb collisions, strangeness is locally (in rapidity) not conserved. The present comparison to the data of the WA97 and NA49 collaborations clearly supports the suggestion that conventional (free) hadronic scenarios are unable to describe the observed high (anti-)hyperon yields in central collisions. The doubling of the strangeness to nonstrange suppression factor, gamma_s \approx 0.65, might be interpreted as a signal of a phase of nearly massless particles.
Invited talk at the 7th International Conference on Strangeness in Quark Matter, SQM 2003, Atlantic Beach, North Carolina, USA, 12-17 Mar, 2003. 11 pages, 12 figures. Journal-ref: J.Phys. G30 (2004) S139-S150. We review recent developments in the field of microscopic transport model calculations for ultrarelativistic heavy ion collisions. In particular, we focus on the strangeness production, for example, the phi-meson and its role as a messenger of the early phase of the system evolution. Moreover, we discuss the important e ects of the (soft) field properties on the multiparticle system. We outline some current problems of the models as well as possible solutions to them
Invited talk at the XXXIII International Symposium on Multiparticle Dynamics, Krakow, Poland, 5-11 Sept, 2003. 5 pages, 1 figure Journal-ref: Acta Phys.Polon. B35 (2004) 23-28. We review the recent developments on microscopic transport calculations for two-particle correlations at low relative momenta in ultrarelativistic heavy ion collisions at RHIC.
Invited talk at the International Workshop XXX on Gross Properties of Nuclei and Nuclear Excitations - Ultrarelativistic Heavy-Ion Collisions, Jan. 13-19, 2002, Hirschegg, Austria. Report-no: LBNL-49674. We discuss predictions for the pion and kaon interferometry measurements in relativistic heavy ion collisions at SPS and RHIC energies. In particular, we confront relativistic transport model calculations that include explicitly a first-order phase transition from a thermalized quark-gluon plasma to a hadron gas with recent data from the RHIC experiments. We critically examine the "HBT-puzzle" both from the theoretical as well as from the experimental point of view. Alternative scenarios are briefly explained.
RuO2: a puzzle to be solved
(2023)
Altermagnetism is a topic that has lately been gaining attention and the RuO2 compound is among one of the most studied altermagnetic candidates. However, the survey of available literature on RuO2 properties suggests that there is no consensus about the magnetism of this material. By performing density functional theory calculations, we show that the electronic properties of stoichiometric RuO2 are described in terms of a smaller Hubbard U within DFT+U than the value required to have magnetism. We further argue that Ru vacancies can actually aid the formation of a magnetic state in RuO2. This in turn suggests that a characterization of the amount of Ru vacancies in experimental samples might help the resolution of the controversy between the different experimental results.
The severity of the COVID-19 pandemic, caused by the SARS-CoV-2 coronavirus, calls for the urgent development of a vaccine. The primary immunological target is the SARS-CoV-2 spike (S) protein. S is exposed on the viral surface to mediate viral entry into the host cell. To identify possible antibody binding sites not shielded by glycans, we performed multi-microsecond molecular dynamics simulations of a 4.1 million atom system containing a patch of viral membrane with four full-length, fully glycosylated and palmitoylated S proteins. By mapping steric accessibility, structural rigidity, sequence conservation and generic antibody binding signatures, we recover known epitopes on S and reveal promising epitope candidates for vaccine development. We find that the extensive and inherently flexible glycan coat shields a surface area larger than expected from static structures, highlighting the importance of structural dynamics in epitope mapping.
Living cells constantly remodel the shape of their lipid membranes. In the endo-plasmic reticulum (ER), the reticulon homology domain (RHD) of the reticulophagy regulator 1 (RETR1/FAM134B) forms dense autophagic puncta that are associated with membrane removal by ER-phagy. In molecular dynamics (MD) simulations, we find that FAM134B-RHD spontaneously forms clusters, driven in part by curvature-mediated attraction. At a critical size, the FAM134B-RHD clusters induce the formation of membrane buds. The kinetics of budding depends sensitively on protein concentration and bilayer asymmetry. Our MD simulations shed light on the role of FAM134B-RHD in ER-phagy and show that membrane asymmetry can be used to modulate the kinetics barrier for membrane remodeling.
Experiment NA49 at the Cern SPS uses a large acceptance detector for a systematic study of particle yields and correlations in nucleus-nucleus, nucleon-nucleus and nucleon-nucleon collisions. Preliminary results for Pb+Pb collisions at 40, 80 and 158 A*GeV beam energy are shown and compared to measurements at lower and higher energies.
During infection the SARS-CoV-2 virus fuses its viral envelope with cellular membranes of its human host. Initial contact with the host cell and membrane fusion are both mediated by the viral spike (S) protein. Proteolytic cleavage of S at the S2′ site exposes its 40 amino acid long fusion peptide (FP). Binding of the FP to the host membrane anchors the S2 domain of S in both the viral and the host membrane. The reorganization of S2 then pulls the two membranes together. Here we use molecular dynamics (MD) simulations to study the two core functions of the SARS-CoV-2 FP: to attach quickly to cellular membranes and to form an anchor strong enough to withstand the mechanical force during membrane fusion. In eight 10 μs-long MD simulations of FP in proximity to endosomal and plasma membranes, we find that FP binds spontaneously to the membranes and that binding proceeds predominantly by insertion of two short amphipathic helices into the membrane interface. Connected via a flexible linker, the two helices can bind the membrane independently, yet binding of one promotes the binding of the other by tethering it close to the target membrane. By simulating mechanical pulling forces acting on the C-terminus of the FP we then show that the bound FP can bear forces up to 250 pN before detaching from the membrane. This detachment force is more than ten-fold higher than an estimate of the force required to pull host and viral membranes together for fusion. We identify a fully conserved disulfide bridge in the FP as a major factor for the high mechanical stability of the FP membrane anchor. We conclude, first, that the sequential binding of two short amphipathic helices allows the SARS-CoV-2 FP to insert quickly into the target membrane, before the virion is swept away after shedding the S1 domain connecting it to the host cell receptor. Second, we conclude that the double attachment and the conserved disulfide bridge establish the strong anchoring required for subsequent membrane fusion. Multiple distinct membrane-anchoring elements ensure high avidity and high mechanical strength of FP-membrane binding.
Gasdermin-D (GSDMD) is the ultimate effector of pyroptosis, a form of programmed cell death associated with pathogen invasion and inflammation. After proteolytic cleavage by caspases activated by the inflammasome, the GSDMD N-terminal domain (GSDMDNT) assembles on the inner leaflet of the plasma membrane and induces the formation of large membrane pores. We use atomistic molecular dynamics simulations to study GSDMDNT monomers, oligomers, and rings in an asymmetric plasma membrane mimetic. We identify distinct interaction motifs of GSDMDNT with phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) and phosphatidylserine (PS) head-groups and describe differential lipid binding between the pore and prepore conformations. Oligomers are stabilized by shared lipid binding sites between neighboring monomers acting akin to double-sided tape. We show that already small GSDMDNT oligomers form stable, water-filled and ion-conducting membrane pores bounded by curled beta-sheets. In large-scale simulations, we resolve the process of pore formation by lipid detachment from GSDMDNT arcs and lipid efflux from partial rings. We find that that high-order GSDMDNT oligomers can crack under the line tension of 86 pN created by an open membrane edge to form the slit pores or closed GSDMDNT rings seen in experiment. Our simulations provide a detailed view of key steps in GSDMDNT-induced plasma membrane pore formation, including sublytic pores that explain nonselective ion flux during early pyroptosis.
We propose to measure azimuthal correlations of heavy-flavor hadrons to address the status of thermalization at the partonic stage of light quarks and gluons in high-energy nuclear collisions. In particular, we show that hadronic interactions at the late stage cannot significantly disturb the initial back-to-back azimuthal correlations of DDbar pairs. Thus, a decrease or the complete absence of these initial correlations does indicate frequent interactions of heavy-flavor quarks and also light partons in the partonic stage, which are essential for the early thermalization of light partons.
Recurrent cortical network dynamics plays a crucial role for sequential information processing in the brain. While the theoretical framework of reservoir computing provides a conceptual basis for the understanding of recurrent neural computation, it often requires manual adjustments of global network parameters, in particular of the spectral radius of the recurrent synaptic weight matrix. Being a mathematical and relatively complex quantity, the spectral radius is not readily accessible to biological neural networks, which generally adhere to the principle that information about the network state should either be encoded in local intrinsic dynamical quantities (e.g. membrane potentials), or transmitted via synaptic connectivity. We present two synaptic scaling rules for echo state networks that solely rely on locally accessible variables. Both rules work online, in the presence of a continuous stream of input signals. The first rule, termed flow control, is based on a local comparison between the mean squared recurrent membrane potential and the mean squared activity of the neuron itself. It is derived from a global scaling condition on the dynamic flow of neural activities and requires the separability of external and recurrent input currents. We gained further insight into the adaptation dynamics of flow control by using a mean field approximation on the variances of neural activities that allowed us to describe the interplay between network activity and adaptation as a two-dimensional dynamical system. The second rule that we considered, variance control, directly regulates the variance of neural activities by locally scaling the recurrent synaptic weights. The target set point of this homeostatic mechanism is dynamically determined as a function of the variance of the locally measured external input. This functional relation was derived from the same mean-field approach that was used to describe the approximate dynamics of flow control.
The effectiveness of the presented mechanisms was tested numerically using different external input protocols. The network performance after adaptation was evaluated by training the network to perform a time delayed XOR operation on binary sequences. As our main result, we found that flow control can reliably regulate the spectral radius under different input statistics, but precise tuning is negatively affected by interneural correlations. Furthermore, flow control showed a consistent task performance over a wide range of input strengths/variances. Variance control, on the other side, did not yield the desired spectral radii with the same precision. Moreover, task performance was less consistent across different input strengths.
Given the better performance and simpler mathematical form of flow control, we concluded that a local control of the spectral radius via an implicit adaptation scheme is a realistic alternative to approaches using classical “set point” homeostatic feedback controls of neural firing.
Author summary How can a neural network control its recurrent synaptic strengths such that network dynamics are optimal for sequential information processing? An important quantity in this respect, the spectral radius of the recurrent synaptic weight matrix, is a non-local quantity. Therefore, a direct calculation of the spectral radius is not feasible for biological networks. However, we show that there exist a local and biologically plausible adaptation mechanism, flow control, which allows to control the recurrent weight spectral radius while the network is operating under the influence of external inputs. Flow control is based on a theorem of random matrix theory, which is applicable if inter-synaptic correlations are weak. We apply the new adaption rule to echo-state networks having the task to perform a time-delayed XOR operation on random binary input sequences. We find that flow-controlled networks can adapt to a wide range of input strengths while retaining essentially constant task performance.
Recurrent cortical network dynamics plays a crucial role for sequential information processing in the brain. While the theoretical framework of reservoir computing provides a conceptual basis for the understanding of recurrent neural computation, it often requires manual adjustments of global network parameters, in particular of the spectral radius of the recurrent synaptic weight matrix. Being a mathematical and relatively complex quantity, the spectral radius is not readily accessible to biological neural networks, which generally adhere to the principle that information about the network state should either be encoded in local intrinsic dynamical quantities (e.g. membrane potentials), or transmitted via synaptic connectivity. We present two synaptic scaling rules for echo state networks that solely rely on locally accessible variables. Both rules work online, in the presence of a continuous stream of input signals. The first rule, termed flow control, is based on a local comparison between the mean squared recurrent membrane potential and the mean squared activity of the neuron itself. It is derived from a global scaling condition on the dynamic flow of neural activities and requires the separability of external and recurrent input currents. We gained further insight into the adaptation dynamics of flow control by using a mean field approximation on the variances of neural activities that allowed us to describe the interplay between network activity and adaptation as a two-dimensional dynamical system. The second rule that we considered, variance control, directly regulates the variance of neural activities by locally scaling the recurrent synaptic weights. The target set point of this homeostatic mechanism is dynamically determined as a function of the variance of the locally measured external input. This functional relation was derived from the same mean-field approach that was used to describe the approximate dynamics of flow control.
The effectiveness of the presented mechanisms was tested numerically using different external input protocols. The network performance after adaptation was evaluated by training the network to perform a time delayed XOR operation on binary sequences. As our main result, we found that flow control can reliably regulate the spectral radius under different input statistics, but precise tuning is negatively affected by interneural correlations. Furthermore, flow control showed a consistent task performance over a wide range of input strengths/variances. Variance control, on the other side, did not yield the desired spectral radii with the same precision. Moreover, task performance was less consistent across different input strengths.
Given the better performance and simpler mathematical form of flow control, we concluded that a local control of the spectral radius via an implicit adaptation scheme is a realistic alternative to approaches using classical “set point” homeostatic feedback controls of neural firing.
Author summary How can a neural network control its recurrent synaptic strengths such that network dynamics are optimal for sequential information processing? An important quantity in this respect, the spectral radius of the recurrent synaptic weight matrix, is a non-local quantity. Therefore, a direct calculation of the spectral radius is not feasible for biological networks. However, we show that there exist a local and biologically plausible adaptation mechanism, flow control, which allows to control the recurrent weight spectral radius while the network is operating under the influence of external inputs. Flow control is based on a theorem of random matrix theory, which is applicable if inter-synaptic correlations are weak. We apply the new adaption rule to echo-state networks having the task to perform a time-delayed XOR operation on random binary input sequences. We find that flow-controlled networks can adapt to a wide range of input strengths while retaining essentially constant task performance.