Refine
Year of publication
- 2001 (153) (remove)
Document Type
- Article (153) (remove)
Language
- English (153) (remove)
Has Fulltext
- yes (153)
Keywords
- Englisch (6)
- Polnisch (4)
- Metapher (2)
- Zweitsprachenerwerb (2)
- 16S mtDNA (1)
- 16S rRNA (1)
- 1st order liquid–gas phase transition (1)
- 2-deoxy-D-ribose (1)
- Alzheimer’s disease (1)
- Amerikanisches Englisch (1)
Institute
- Medizin (19)
- Physik (13)
- Institut für Deutsche Sprache (IDS) Mannheim (11)
- Informatik (5)
- Mathematik (4)
- Biowissenschaften (3)
- Georg-Speyer-Haus (3)
- Extern (2)
- Pharmazie (2)
- Rechtswissenschaft (2)
Activated blood coagulation factor (F) XIII (FXIIIa), a transglutaminase comprised of two A and two B subunits in a tetrameric structure (A2B2) of 320 kd, has a central role in the haemostatic system by cross-linking fibrin monomers in the final step of blood coagulation, thus stabilizing the fibrin clot and increasing its resistance to fibrinolysis. In addition, FXIIIa is implicated in the cross-linking of several other proteins, such as a-2-antiplasmin, fibronectin, and collagen. The impact of genetic variations of FXIII in thrombotic disorders has not been studied until recently, when a common polymorphism was described as a new candidate genetic factor influencing the risk of thrombotic diseases. This polymorphism results from a G to T transition in codon 34 of exon 2 of the catalytic FXIII A-subunit gene, leading to the substitution of leucine for valine (FXHIVal34Leu) close to the thrombin activation site. Genotype at this polymorphism is closely related to FXIII fibrin cross-linking activity, and FXIIILeu is associated with increased thrombin activation of FXIII with associated changes in fibrin structure. Initially, FXIII Val34Leu was shown to be significantly less common in British patients with a history of myocardial infarction than in controls, suggesting for the first time a new role for FXIII in a polygenic thrombotic disease. In addition to its proposed protective effect against thrombotic heart diseases, the Leu34 allele has also been correlated with protection against venous thromboembolism and thrombotic cerebral artery occlusion, whereas it seems to confer an increased risk for intracerebral haemorrhage. Because this genetic variation is associated with a higher activity of the enzyme, the mechanism accounting for the putative anti-thrombotic effect of FXIII Val34Leu is not well understood. However, it has been hypothesized that increased rates of FXIII activation could lead to ineffective cross-linking, or that the kinetics of the cross-linking reactions may be disrupted because of the effects of FXIIIa on other proteins. Previous s'tudies have demonstrated that the FXIII Val34Leu polymorphism is highly prevalent in ^[[200~several Caucasian populations, with reported Leu34 allele frequencies of around 0.25, whereas it is less prevalent in populations of African and Asian origin. The known significant ethnic heterogeneity linked to the FXIII Val34Leu polymorphism is of relevance when analyzing its role in vascular diseases. In summary, published studies indicate that blood coagulation FXIII is involved in the multifactorial pathogenesis of vascular diseases and suggest a contribution of FXIII Val34Leu in determining the risk of myocardial infarction, stroke and venous thromboembolism.
Herpes genitalis is caused mainly by herpes simplex virus type 2 (HSV-2) and to a lesser extent but with increasing frequency, by herpes simplex virus type 1 (HSV-1). Today, the diagnosis of genital herpes is based "on laboratory methods. Serology is useful to distinguish primary infection from latent infection and for seroepidemiological investigations. Newer type-specific antibody tests based on single recombinant or purified viral antigens have a higher sensitivity and specificity for detecting anti HSV-2 antibodies. The tests also allow the discrimination between HSV-1 or -2 specific antibodies. Since serology is not able to recognize reactivation, isolation in cell culture remains the standard. If cell culture is not available or optimal transport is not possible and rapid results are needed, direct antigen detection, or in selected cases, the highly sensitive and specific PCR should be used.
Reversible phosphorylation plays important roles in G protein-coupled receptor signaling, desensitization, and endocytosis, yet the precise location and role of in vivo phosphorylation sites is unknown for most receptors. Using metabolic 32P labeling and phosphopeptide sequencing we provide a complete phosphorylation map of the human bradykinin B2 receptor in its native cellular environment. We identified three serine residues, Ser(339), Ser(346), and Ser(348), at the C-terminal tail as principal phosphorylation sites. Constitutive phosphorylation occurs at Ser(348), while ligand-induced phosphorylation is found at Ser(339) and Ser(346)/Ser(348) that could be executed by several G protein-coupled receptor kinases. In addition, we found a protein kinase C-dependent phosphorylation of Ser(346) that was mutually exclusive with the basal phosphorylation at Ser(348) and therefore may be implicated in differential regulation of B2 receptor activation. Functional analysis of receptor mutants revealed that a low phosphorylation stoichiometry is sufficient to initiate receptor sequestration while a clustered phosphorylation around Ser(346) is necessary for desensitization of the B2 receptor-induced phospholipase C activation. This was further supported by the specifically reduced Ser(346)/Ser(348) phosphorylation observed upon stimulation with a nondesensitizing B2 receptor agonist. The differential usage of clustered phosphoacceptor sites points to distinct roles of multiple kinases in controlling G protein-coupled receptor function.
In acute myeloid leukemias (AMLs) with t(8;21), the transcription factor AML1 is juxtaposed to the zinc finger nuclear protein ETO (Eight-Twenty-One), resulting in transcriptional repression of AML1 target genes. ETO has been shown to interact with corepressors, such as N-CoR and mSin3A to form complexes containing histone deacetylases. To define regions of ETO required for maximal repressor activity, we analyzed amino-terminal deletions in a transcriptional repression assay. We found that ETO mutants lacking the first 236 amino acids were not affected in their repressor activity, whereas a further deletion of 85 amino acids drastically reduced repressor function and high molecular weight complex formation. This latter mutant can still homodimerize and bind to N-CoR but shows only weak binding to mSin3A. Furthermore, we could show that a "core repressor domain" comprising nervy homology region 2 and its amino- and carboxyl-terminal flanking sequences recruits mSin3A and induces transcriptional repression. These results suggest that mSin3A and N-CoR bind to ETO independently and that both binding sites cooperate to maximize ETO-mediated transcriptional repression. Thus, ETO has a modular structure, and the interaction between the individual elements is essential for the formation of a stable repressor complex and efficient transcriptional repression.
The binding and activation of the discoidin domain receptor 1 by collagen has led to the conclusion that proteins from the extracellular matrix can directly induce receptor tyrosine kinase-mediated signaling cascades. A region in the extracellular domain of DDR1 homologous to the Dictyostelium discoideum protein discoidin-I is also present in the secreted human protein RS1. Mutations in RS1 cause retinoschisis, a genetic disorder characterized by ablation of the retina. By introducing point mutations into the discoidin domain of DDR1 at positions homologous to the retinoschisis mutations, ligand binding epitopes in the discoidin domain of DDR1 were mapped. Surprisingly, some residues only affected receptor phosphorylation, whereas others influenced both collagen-binding and receptor activation. Furthermore, two truncated DDR1 variants, lacking either the discoidin domain or the stalk region between the discoidin and transmembrane domain, were generated. We showed that (i) the discoidin domain was necessary and sufficient for collagen binding, (ii) only the region between discoidin and transmembrane domain was glycosylated, and (iii) the entire extracellular domain was essential for transmembrane signaling. Using these results, we were able to predict key sites in the collagen-binding epitope of DDR1 and to suggest a potential mechanism of signaling.
The core of photosystem I (PS1) is composed of the two related integral membrane polypeptides, PsaA and PsaB, which bind two symmetrical branches of cofactors, each consisting of two chlorophylls and a phylloquinone, that potentially link the primary electron donor and the tertiary acceptor. In an effort to identify amino acid residues near the phylloquinone binding sites, all tryptophans and histidines that are conserved between PsaA and PsaB in the region of the 10th and 11th transmembrane alpha-helices were mutated in Chlamydomonas reinhardtii. The mutant PS1 reaction centers appear to assemble normally and possess photochemical activity. An electron paramagnetic resonance (EPR) signal attributed to the phylloquinone anion radical (A(1)(-)) can be observed either transiently or after illumination of reaction centers with pre-reduced iron-sulfur clusters. Mutation of PsaA-Trp(693) to Phe resulted in an inability to photo-accumulate A(1)(-), whereas mutation of the analogous tryptophan in PsaB (PsaB-Trp(673)) did not produce this effect. The PsaA-W693F mutation also produced spectral changes in the time-resolved EPR spectrum of the P(700)(+) A(1)(-) radical pair, whereas the analogous mutation in PsaB had no observable effect. These observations indicate that the A(1)(-) phylloquinone radical observed by EPR occupies the phylloquinone-binding site containing PsaA-Trp(693). However, mutation of either tryptophan accelerated charge recombination from the terminal Fe-S clusters.
The function of gene sll0033 from Synechocystis 6803 which is homologous to the bacterial crtI-type phytoene desaturase genes was elucidated as a novel carotene isomerase. Escherichia coli transformed with all genes necessary for the formation of ζ-carotene and expressing a ζ-carotene desaturase synthesized the positional isomer prolycopene (7,9,7′,9′Z lycopene) which cannot be cyclized in the subsequent reactions to a- and β-carotene. Upon cotransformation with sll0033, the formation of all-E lycopene is mediated instead.
Toll-like receptors (TLRs) have been found to be key elements in pathogen recognition by the host immune system. Dendritic cells (DCs) are crucial for both innate immune responses and initiation of acquired immunity. Here we focus on the potential involvement of TLR ligand interaction in DC maturation. TLR2 knockout mice and mice carrying a TLR4 mutation (C3H/HeJ) were investigated for DC maturation induced by peptidoglycan (PGN), lipopolysaccharide (LPS), or lipoteichoic acids (LTAs). All stimuli induced maturation of murine bone marrow-derived DCs in control mice. TLR2−/− mice lacked maturation upon stimulation with PGN, as assessed by expression of major histocompatibility complex class II, CD86, cytokine, and chemokine production, fluorescein isothiocyanate-dextran uptake, and mixed lymphocyte reactions, while being completely responsive to LPS. A similar lack of maturation was observed in C3H/HeJ mice upon stimulation with LPS. DC maturation induced by LTAs from two different types of bacteria was severely impaired in TLR2−/−, whereas C3H/HeJ mice responded to LTAs in a manner similar to wild-type mice. We demonstrate that DC maturation is induced by stimuli from Gram-positive microorganisms, such as PGN and LTA, with similar efficiency as by LPS. Finally, we provide evidence that TLR2 and TLR4 interaction with the appropriate ligand is essential for bacteria-induced maturation of DCs.
Nitric oxide (NO) plays an important role in the regulation of the functional integrity of the endothelium. The intracellular reaction of NO with reactive cysteine groups leads to the formation of S-nitrosothiols. To investigate the regulation of S-nitrosothiols in endothelial cells, we first analyzed the composition of the S-nitrosylated molecules in endothelial cells. Gel filtration revealed that more than 95% of the detected S-nitrosothiols had a molecular mass of more than 5000 Da. Moreover, inhibition of de novosynthesis of glutathione using N-butyl-sulfoximine did not diminish the overall cellular S-NO content suggesting that S-nitrosylated glutathione quantitatively plays only a minor role in endothelial cells. Having demonstrated that most of the S-nitrosothiols are proteins, we determined the regulation of the S-nitrosylation by pro-inflammatory and pro-atherogenic factors, such as TNFα and mildly oxidized low density lipoprotein (oxLDL). TNFα and oxLDL induced denitrosylation of various proteins as assessed by Saville-Griess assay, by immunostaining with an anti-S-nitrosocysteine antibody, and by a Western blot approach. Furthermore, the caspase-3 p17 subunit, which has previously been shown to be S-nitrosylated and thereby inhibited, was denitrosylated by TNFα treatment suggesting thatS-nitrosylation and denitrosylation are important regulatory mechanisms in endothelial cells contributing to the integrity of the endothelial cell monolayer.
The ratios of the oxidative phosphorylation complexes NADH:ubiquinone reductase (complex I), succinate:ubiquinone reductase (complex II), ubiquinol:cytochrome c reductase (complex III), cytochrome c oxidase (complex IV), and F1F0-ATP synthase (complex V) from bovine heart mitochondria were determined by applying three novel and independent approaches that gave consistent results: 1) a spectrophotometric-enzymatic assay making use of differential solubilization of complexes II and III and parallel assays of spectra and catalytic activities in the samples before and after ultracentrifugation were used for the determination of the ratios of complexes II, III, and IV; 2) an electrophoretic-densitometric approach using two-dimensional electrophoresis (blue native-polyacrylamide gel electrophoresis and SDS-polyacrylamide gel electrophoresis) and Coomassie blue-staining indices of subunits of complexes was used for determining the ratios of complexes I, III, IV, and V; and 3) two electrophoretic-densitometric approaches that are independent of the use of staining indices were used for determining the ratio of complexes I and III. For complexes I, II, III, IV, and V in bovine heart mitochondria, a ratio 1.1 +/- 0.2:1.3 +/- 0.1:3:6.7 +/- 0.8:3.5 +/- 0.2 was determined.
The inhibitory glycine receptor (GlyR) in developing spinal neurones is internalized efficiently upon antagonist inhibition. Here we used surface labeling combined with affinity purification to show that homopentameric α1 GlyRs generated inXenopus oocytes are proteolytically nicked into fragments of 35 and 13 kDa upon prolonged incubation. Nicked GlyRs do not exist at the cell surface, indicating that proteolysis occurs exclusively in the endocytotic pathway. Consistent with this interpretation, elevation of the lysosomal pH, but not the proteasome inhibitor lactacystin, prevents GlyR cleavage. Prior to internalization, α1 GlyRs are conjugated extensively with ubiquitin in the plasma membrane. Our results are consistent with ubiquitination regulating the endocytosis and subsequent proteolysis of GlyRs residing in the plasma membrane. Ubiquitin-conjugating enzymes thus may have a crucial role in synaptic plasticity by determining postsynaptic receptor numbers.
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). In this study we have investigated the function of the CBP-associated members of the p160/steroid receptor coactivator family in the transcriptional activation by STAT6. We found that only one of them, NCoA-1, acts as a coactivator for STAT6 and interacts directly with the transactivation domain of STAT6. The N-terminal part of NCoA-1 interacts with the far C-terminal part of the STAT6 transactivation domain but does not interact with the other members of the STAT family. This domain of NCoA-1 has a strong inhibitory effect on STAT6-mediated transactivation when overexpressed in cells, illustrating the importance of NCoA-1 for STAT6-mediated transactivation. In addition, we showed that both coactivators CBP and NCoA-1 bind independently to specific regions within the STAT6 transactivation domain. Our results suggest that multiple contacts between NCoA-1, CBP, and STAT6 are required for transcriptional activation. These findings provide new mechanistic insights into how STAT6 can recruit coactivators required for IL-4-dependent transactivation.
We have analyzed a series of eleven mutations in the 49-kDa protein of mitochondrial complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica to identify functionally important domains in this central subunit. The mutations were selected based on sequence homology with the large subunit of [NiFe] hydrogenases. None of the mutations affected assembly of complex I, all decreased or abolished ubiquinone reductase activity. Several mutants exhibited decreased sensitivities toward ubiquinone-analogous inhibitors. Unexpectedly, seven mutations affected the properties of iron-sulfur cluster N2, a prosthetic group not located in the 49-kDa subunit. In three of these mutants cluster N2 was not detectable by electron-paramagnetic resonance spectroscopy. The fact that the small subunit of hydrogenase is homologous to the PSST subunit of complex I proposed to host cluster N2 offers a straightforward explanation for the observed, unforeseen effects on this iron-sulfur cluster. We propose that the fold around the hydrogen reactive site of [NiFe] hydrogenase is conserved in the 49-kDa subunit of complex I and has become part of the inhibitor and ubiquinone binding region. We discuss that the fourth ligand of iron-sulfur cluster N2 missing in the PSST subunit may be provided by the 49-kDa subunit.
We consider J/ψ production in heavy ion collisions at RHIC energies in the statistical coalescence model with exact (canonical ensemble) charm conservation. Charm quark–antiquark pairs are assumed to be created in primary hard parton collisions, but open and hidden charm particles are formed at the hadronization stage according to the laws of statistical mechanics. The dependence of the J/ψ production on both the number of nucleon participants and the collision energy is studied. The model predicts J/ψ suppression for low energies, whereas at the highest RHIC energy the model reveals J/ψ enhancement.
For statistical multifragmentation model the critical indices α′,β,γ′,δ are calculated as functions of the Fisher parameter τ. It is found that these indices have different values than in Fisher's droplet model. Some peculiarities of the scaling relations are discussed. The basic model predicts for the index τ a narrow range of values, 1.799<τ<1.846, which is consistent with two experiments on nuclear multifragmentation.
In high energy p(p)+p interactions the mean multiplicity and transverse mass spectra of neutral mesons from η to ϒ (m≅0.5–10 GeV/c2) and the transverse mass spectra of pions (mT> 1 GeV/c2) reveal a remarkable behaviour: they follow, over more than 10 orders of magnitude, the power-law function: Cm(T)−P. The parameters C and P are energy dependent, but similar for all mesons produced at the same collision energy. This scaling resembles that expected in the statistical description of hadron production: the parameter P plays the role of a temperature and the normalisation constant C is analogous to the system volume. The fundamental difference is, however, in the form of the distribution function. In order to reproduce the experimental results and preserve the basic structure of the statistical approach the Boltzmann factor e−E∗/T appearing in standard statistical mechanics has to be substituted by a power-law factor (E∗/Λ)−P.
Crustal structure at the western end of the North Anatolian Fault Zone from deep seismic sounding
(2001)
The first deep seismic sounding experiment in Northwestern Anatolia was carried out in October 1991 as part of the "German - Turkish Project on Earthquake Prediction Research" in the Mudurnu area of the North Anatolian Fault Zone. The experiment was a joint enterprise by the Institute of Meteorology and Geophysics of Frankfurt University, the Earthquake Research Institute (ERI) in Ankara, and the Turkish Oil Company (TPAO). Two orthogonal profiles, each 120 km in length with a crossing point near Akyazi, were covered in succession by 30 short period tape recording seismograph stations with 2 km station spacing. 12 shots, with charge sizes between 100 and 250 kg, were fired and 342 seismograms out of 360 were used for evaluation. By coincidence an M b = 4.5 earthquake located below Imroz Island was also recorded and provided additional information on Moho and the sub-Moho velocity. A ray tracing method orginally developed by Weber (1986) was used for travel time inversion. From a compilation of all data two generalized crustal models were derived, one with velocity gradients within the layers and one with constant layer velocities. The latter consists of a sediment cover of about 2 km with V p » 3.6 km/s, an upper crystalline crust down to 13 km with V p » 5.9 km/s, a middle crust down to 25 km depth with V p » 6.5 km/s, a lower crust down to 39 km Moho depth with V p » 7.0 km/s and V p » 8.05 km/s below the Moho. The structure of the individual profiles differs slightly. The thickest sediment cover is reached in the Izmit-Sapanca-trough and in the Akyazi basin. Of particular interest is a step of about 4 km in the lower crust near Lake Sapanca and probably an even larger one in the Moho (derived from the Imroz earthquake data). After the catastrophic earthquake of Izmit on 17 August 1999 this significant heterogeneity in crustal structure appears in a new light with regard to the possible cause of the Izmit earthquake. Heterogeneities in structure are frequently also heterogeneities in strength and stress that impede or even lock rupture. The Izmit earthquake is discussed in relation to a large stepover or jog at the North Anatolian Fault.
The present study is the second in a three-part series (the first appearing in <i>Sefarad </i>59 [1999] pp. 3-42; the third being in press) on the phenomenon of Neo- Latin and Romance-Language —Spanish and Portuguese— poetry of the Sephardim in Hamburg and Frankfurt am Main from the early seventeenth to the midnineteenth centuries. Our collection expands the original poetic corpus from twenty-eight to forty-five works. In an historical and critical Introduction to the poems, the authors distinguish the creative genius of a new type of literary discourse, one which meshes neo-classical strophic forms with inspiration from Sephardic orthodox Judaism as it was practiced in the Dutch Netherlands, biblical events and Jewish philosophical constructs. In addition to the evaluation and edition of the poems and, in the cases of Neo-Latin works, their translation to English, the Introduction includes an argument for substantiating book printing of Sephardic-authored books in Frankfurt am Main during the period 1614-1634 as well as sporadically throughout the remainder of the seventeenth century.<br><br>Nuestro estudio representa la segunda parte (la primera apareció en <i>Sefarad</i> 59 [1999] págs. 3-42; la tercera está en prensa) de un trabajo sobre la poesía en latín y lenguas romances —español y portugués— de los sefardíes de Hamburgo y de Frankfurt am Main desde principios del siglo XVII hasta mediados del XVIII. Aquí el <i>corpus poetarum</i> se amplía de veintiocho a cuarenta y cinco obras; estas nuevas poesías evidencian un espíritu neoclasicista mezclado ingeniosamente con un discurso apegado a un judaísmo ortodoxo-sefardí tal como entonces se practicaba en los países protestantes del norte de Europa. En el apartado introductorio, que es tanto descriptivo como evaluativo de la obra poética, se defiende la tesis de que la ciudad protestante de Frankfurt am Main con su feria del libro anual servía como lugar de impresión para ciertas obras producidas por autores sefardíes durante los años 1614-1632 y esporádicamente durante el resto del siglo XVII.
UICC classification accurately predicts overall survival but not recurrence-risk. We report here data of overall and first site-specific recurrence following curative surgery useful for the development of recurrence-oriented preventive target therapies. Patients who underwent resection for gastric cancer were stratified according to curability of surgery [curative (R0) vs non-curative resection], extent of surgery [limited (D1) vs extended (D2) node dissection] and pathological nodal/serosal status. The intent-to-treat principle, log-rank test and Cox regression analysis were used for statistical analysis of time-to-event (recurrence, death) endpoints. Curative resection only produced a chance of cure whereas survival was very poor following non-curative resection (P < 0.0001). For D2 R0 subgroup of patients, a pathological serosa and a node state-based classification into three groups, proved to be of clinical implication. Risk of recurrence after a median follow-up of 92 months was low among patients with both serosa and node-negative cancer (first group; 11%), moderate among those with either serosa or node-positive cancer (second group; 53%) and very high among those with both serosa and node-positive cancer (third group; 83%). In multivariate analysis, the relative risks of recurrence and death from gastric cancer among patients in the second and third groups, as compared to those in the first, were 7.07 (95% CI, 2.36–21.17; P = 0.0002) and 16.19 (95% CI, 5.76–45.54; P < 0.0001) respectively. First site-specific recurrence analysis revealed: low rate of loco-regional recurrence alone (12%), serosa state determinant factor of the site-recurrence (peritoneal for serosa-positive and haematogenous for serosa-negative cancers) and dramatic increase of all types of recurrence by the presence of nodal metastases. Our findings demonstrate that a pathological serosa- and node-based classification is very simple and predicts accurately site-specific recurrence-risks. Furthermore they reveal that risk of recurrence following curative D2 surgery alone is low for serosa- and node-negative cancers, but very high in serosa- and node-positive cancers suggesting the need for new therapeutic strategies in this subgroup of patients.
Aim: To study the transepithelial transport characteristics of the polyamine putrescine in human intestinal Caco-2 cell monolayers to elucidate the mechanisms of the putrescine intestinal absorption.
Methods: The transepithelial transport and the cellular accumulation of putrescine was measured using Caco-2 cell monolayers grown on permeable filters.
Results: Transepithelial transport of putrescine in physiological concentrations ( > 0.5 mM) from the apical to basolateral side was linear. Intracellular accumulation of putrescine was higher in confluent than in fully differentiated Caco-2 cells, but still negligible (less than 0.5%) of the overall transport across the monolayers in apical to basolateral direction.EGF enhanced putrescine accumulation in Caco-2 cells by four fold, as well as putrescine conversion to spermidine and spermine by enhancing the activity of S adenosylmethionine decarboxylase. However, EGF did not have any significant influence on putrescine flux across the Caco- 2 cell monolayers. Excretion of putrescine from Caco-2 cells into the basolateral medium did not exceed 50 picomoles, while putrescine passive flux from the apical to the basolateral chamber, contributed hundreds of micromoles polyamines to the basolateral chamber.
Conclusion: Transepithelial transport of putrescine across Caco-2 cell monolayers occurs in passive diffusion, and is not influenced when epithelial cells are stimulated to proliferate by a potent mitogen such as EGF.
We may consider narratology - the structural study of narratives - in two ways, each of them implying a slightly different 'before' and 'after'. First, this important endeavor in 20th century literary studies may be regarded as the study of a specific narrative 'logic', the formal structures that unite all narratives, fictional and factual, literary and non-literary. Secondly, narratology may be regarded as the study of specific 'texts' with specific cultural functions - storehouses of 'memory' on the one hand and, on the other, 'meaning-generating devices' integrating human action with time and place, ending up in cognition, identity, values, pragmatic norms, etc. In spite of the fact that both trends diminish the role of the specific medium of a given narrative, focusing instead on a general logic or on general functions, both of them refer 'de facto' to literature as a primary field of study; moreover, they are both children, twins one might argue, of the linguistic turn at the turn of the last century, and they both 'de facto' constantly refer to language as a primary field of study. This paradigmatic shift emphasized a specific medium and its specific logic in a general perspective without losing grip of the specificity. A lesson may be learned if we quickly repaint the history and perspective of this turn in a few broad strokes.
The point of my explanation is simply that in its "deep-structure" even 'A Handful of Dust' (and 'a fortiori', as we shall see, other novels by Waugh) attaches itself to the mode of the historical novel, which is only in a very qualified way the descendant of the epic, as Lukacs would have us believe.
Bipartite graphs occur in many parts of mathematics, and their embeddings into orientable compact surfaces are an old subject. A new interest comes from the fact that these embeddings give dessins d’enfants providing the surface with a unique structure as a Riemann surface and algebraic curve. In this paper, we study the (surprisingly many different) dessins coming from the graphs of finite cyclic projective planes. It turns out that all reasonable questions about these dessins — uniformity, regularity, automorphism groups, cartographic groups, defining equations of the algebraic curves, their fields of definition, Galois actions — depend on cyclic orderings of difference sets for the projective planes. We explain the interplay between number theoretic problems concerning these cyclic ordered difference sets and topological properties of the dessin like e.g. the Wada property that every vertex lies on the border of every cell.
Depth hermeneutics—as developed by LORENZER within the framework of the Frankfort School's program of critical social research—represents a methodological and systematic approach to psychoanalytic research. The new ways and means by which a neo-Nazi utilises his visit to the Auschwitz Memorial to arouse further anti-Semitism are to be investigated by means of a scene-by-scene interpretation of his filmed appearances—first as a good-mooded tourist, then as a volatile right-wing extremist, as competent expert, and as rebellious adolescent. The aim is to demonstrate how the meaning of these role plays develops within the tension between a manifest and a latent significance. The results of this process of interpretations form the basis for clarifying the question: what patterns of socialisation are used by this "yuppie-neo-Nazi" to fascinate particularly adolescents?? In conclusion, the way in which through his post-modern film-production the producer turns Auschwitz into a test-ground where the neo-Nazi can do "a merry dance on the volcano", is analysed.
The cyanoprokaryotic genus Romeria is traditionally classified as the simplest filamentous cyanobacterium, occurring scarcely in freshwater reservoirs. Three species were described originally, which are known from the temperate zone, and which are usually cited in all identification manuals of this cyanoprokaryotic group. However, other species were found recently, also in other biotopes (benthos, cryoseston, marine plankton), and now the number of registered species increased to 19. The problem is, that they were not yet isolated in culture, and nothing is known about ultrastructure and molecular characters of any Romeria species. Recently, two mass developments of two planktic species were found in freshwater reservoirs in Brazil and in Czech Republic, which enabled, at least, the study of their morphological variability and cell structure. It was found, that Romeria is evidently very interesting cyanobacterium with close relations to other simple filamentous species, as well as to simple coccoid types living in solitary, rod-like cells. The review of the whole genus, which is included in this article, is necessary for further research of this important cyanobacterial type.
Germination of fresh seeds of the rare arid zone shrub Grevillea kennedyana F. Muell. (family Proteaceae) is most successful at 10°C with light, and 15°C with or without light. The seeds were non-dormant and did not require further germination enhancing substances, such as smoke or fire to achieve > 80% success. These results do not support the role of fire in the management strategies suggested in the Recovery Plan for this species. Grevillea kennedyana seeds are orthodox and can be dried at 15°C and 15% RH and stored at 4 and -18°C for a short period. In relating the results of this trial to the germination requirements of Grevillea kennedyana in the field, it appears that successful germination will require low temperatures (i.e. < 15°C in winter) at the time of seasonal rainfall. Further studies are required to determine the cause of the poor seedling recruitment observed in the field.
Doryanthes palmeri is a giant, flowering succulent herb endemic to north-east NSW and south-east Queensland. Prior to this study, only two D. palmeri sites had been reported in NSW. This study revealed a further nine sites, all of which are restricted to the Mt Warning caldera.
Doryanthes palmeri occurs on infertile lithosols or grows as a lithophyte on bare rock. It occurs in a narrow band of vegetation along the cliff-tops and on steep cliff-faces or rocky ledges in montane heath next to subtropical rainforest, wet sclerophyll forest or warm temperate forest. There are around 6000 mature D. palmeri plants in north-east NSW. Populations at each site occur as clusters on a relatively small amount of the available habitat. The area of occupancy of D. palmeri is less than 1 km2 with an average distance between sites of 6.3 km. However, the distribution consists of four groups of populations with an average of 15 km between the groups suggesting a poor ability to disperse.
There appear to be limits to the extent that plants can expand at some sites which are due mainly to low recruitment of juveniles into the population, illegal seed harvesting and the competition of faster growing native or weed species. The present populations, therefore, are restricted to their current exposed positions. The small restricted, fragmented distribution and current threats to the population suggests that D. palmeri should be regarded as a vulnerable species.
A 0.6 ha area in North Wahroonga, Sydney NSW, where the plant and soil cover had been completely removed to expose the underlying sandstone rock surface, was examined in 1997, c. 70 years after the disturbance ceased. The area has remained relatively undisturbed since the 1920s, and the revegetation has been allowed to proceed unhindered. In total, 146 species were encountered in and around the area, 126 of them occurring in the quarried area. Twenty-six of these species are not native to the area, but they occurred almost exclusively in the south-east quarry working, which is adjacent to the closest residential area. The three quarry workings were clearly floristically distinct from each other, with the south-east quarry working differing from the other two in having many unique species (mainly the introduced species) and the east working being floristically de-pauperate. None of the measured soil physical or chemical variables was particularly correlated with the variation in floristic composition. There was a partial distinction between the plant species composition of the quarried area and the adjacent undisturbed area, with 17% of the native species encountered not occurring in the quarried area and a further 10% showing a significantly lower abundance in this area. However, the distinctive south-east quarry working was floristically no more different from the rest of the quarry than was the native area last burnt in 1990 from the native area last burnt in 1968, and the quadrats in the long-unburnt native area were rather similar in species composition to those of the north and east quarry workings. However, many of the species in long-unburnt vegetation will be represented in the community solely by a soil seedbank, and so this comparison of above-ground vegetation may be artificial. The soil structure and fertility both showed no consistent differences between the native area and the quarried area.
Native plant species were recorded on a small mown remnant of Blue Gum High Forest in Observatory Park, Pennant Hills, in northwestern Sydney, in 1979 and 1988. In 1989 an area was set aside in the Park, in which mowing was stopped and bush regeneration commenced and is ongoing. Native species were recorded 5 times over the following 11 years, during which time the number of native species recorded rose from 47 to 126. The result demonstrates the potential for mown bushland sites containing native species to regenerate with appropriate treatment.
Ecological data in tabular form are provided on 325 plant species of the families Rutaceae to Zygophyllaceae, 236 native and 89 exotics, occurring in the Sydney region, defined by the Central Coast and Central Tablelands botanical subdivisions of New South Wales (approximately bounded by Lake Macquarie, Orange, Crookwell and Nowra). Relevant Local Government Areas are Auburn, Ashfield, Bankstown, Bathurst, Baulkham Hills, Blacktown, Blayney, Blue Mountains, Botany, Burwood, Cabonne, Camden, Campbelltown, Canterbury, Cessnock, Concord, Crookwell, Drummoyne, Evans, Fairfield, Greater Lithgow, Gosford, Hawkesbury, Holroyd, Hornsby, Hunters Hill, Hurstville, Kiama, Kogarah, Ku-Ring-Gai, Lake Macquarie, Lane Cove, Leichhardt, Liverpool, Manly, Marrickville, Mosman, Mulwaree, North Sydney, Oberon, Orange, Parramatta, Penrith, Pittwater, Randwick, Rockdale, Ryde, Rylstone, Shellharbour, Shoalhaven, Singleton, South Sydney, Strathfield, Sutherland, Sydney City, Warringah, Waverley, Willoughby, Wingecarribee, Wollondilly, Wollongong, Woollahra and Wyong. The study area falls within the Sydney Basin IBRA Bioregion.
Families are: Rutaceae, Salicaceae, Sambucaceae, Santalaceae, Sapindaceae, Sapotaceae, Scrophulariaceae, Selaginaceae, Simaroubaceae, Solanaceae, Stackhousiaceae, Sterculiaceae, Stylidiaceae, Symplocaceae, Thymelaeaceae, Tremandraceae, Tropaeolaceae, Ulmaceae, Urticaceae, Valerianaceae, Verbenaceae, Viburnaceae, Violaceae, Viscaceae, Vitaceae, Winteraceae, Zygophyllaceae.
Data are derived from herbarium collections, literature and field observations. It is hoped that the many, often alarming gaps in the information available will stimulate much-needed research into the ecology of more of the species. Information is provided so far as available to us for each plant species in the following categories:
Life History: Growth form, vegetative spread, longevity, primary juvenile period (time from germination to fruiting), reproduction, flowering and fruiting times, fruit/seed type, dispersal, establishment and growth, fire response, interaction with other organisms.
Distribution: Status/origin (native/naturalised), botanical subregions, distribution in Sydney area, selected locations.
Habitat: Habitat, altitude, annual rainfall, typical local abundance, vegetation, substrate, exposure.
Conservation: Conservation status.
Habitat details and population sizes are provided for six populations of the rare leafless saprophytic terrestrial orchid Cryptostylis hunteriana Nichols (family Orchidaceae) from the Wyong-southern Lake Macquarie area of New South Wales. The extent of potential habitat based on known sites on the Central Coast is examined in a regional context, and annual targeted surveys in similar habitat are suggested. Apart from a population of unknown size in Ku-ring-gai Chase National Park, no populations of Cryptostylis hunteriana are at present within conservation reserves on the Central Coast. The paucity of records in the region suggests that any information about ecology or habitat will be beneficial to conservation and management. Adoption of a landscape approach may be the most appropriate avenue to ensure long term conservation. Due to the limited records, the poor representation in reserves and the species' cryptic nature, assessment and survey of all known populations of Cryptostylis hunteriana in New South Wales should be undertaken, prior to a review of its current conservation status.
The Rutaceae is an important worldwide family. In Australia, members of the family have radiated across the landscape from rainforests, moist and dry eucalypt forests, heaths, alpine areas and deserts.
Some 71 native taxa (in 14 genera) of Rutaceae occur in the Sydney Region, representing some 3% of the native vascular plant flora of the region. Species richness is greatest in heaths, woodlands and dry forests on sandstone derived soils. A number of species occur in moist forest, while a few species occur in riparian forests, rainforests or forests on clay soils or soils derived from granite. The most species rich genera are Boronia and Zieria (both 18 species). Fifteen species in the region are rare or threatened at the state or national level, with a further 2 species poorly known and likely candidates as threatened species. There are 17 species endemic to the Sydney region, 11 of which are rare or threatened.
Most species flower in winter to spring with seeds released in October to December. There are two basic modes of dispersal in the family in the Sydney Region. Firstly, a few species, generally associated with rainforests, disperse seeds widely via fleshy fruits that are taken by birds and probably mammals. Secondly, most Rutaceae species have limited dispersal ability and have short range initial ballistic dispersal of seeds from fruits at maturity followed by secondary seed dispersal primarily by ants. In this latter group, seeds are generally dispersed less than a few metres. There is a high level of seed dormancy at seed release. Members of the Rutaceae are likely to have persistent soil seedbanks with germination linked to fire, except perhaps for species in rainforest or rainforest margins (where the nature of possible seedbanks is unknown). Heating of the soil during fire is one mechanism for breaking seed dormancy and allowing germination. Other mechanisms, i.e. smoke and the interaction of fire related germination cues may also be important. Fire is a widespread disturbance affecting vegetation in the Sydney Region. Within the Rutaceae in the Sydney region, a mixture of fire-sensitive and resprouting species occur, although details for many species are lacking. To maintain the floristic diversity in the family, effective management of such plant communities requires sufficient times between fires for seedlings to flower and replenish the soil seedbanks, as well as for juveniles of resprouting species to become fire-resistant.
The ecology of Rutaceae species remains poorly understood, a pattern typical across Australia, with a few notable exceptions. There have been no comprehensive demographic studies of members of the family in Sydney, and only limited attempts to examine aspects of the biology of the species in the family. In particular, the seed biology and ecology of the family and the impact of fire on species are poorly understood. This review poses a number of questions for research on members of the Rutaceae.
The vegetation of Kinchega National Park (latitude 32°18'–32°40'S and longitude 142°10'–142°25'E) in far western New South Wales was assessed using intensive quadrat sampling and mapped using extensive ground truthing and interpretation of aerial photographs and Landsat Thematic Mapper satellite images. Three hundred and fifty two species of vascular plants were recorded from this survey, which, together with other records indicates the presence of 503 species from 69 families including 100 (20%) exotic species. Fifteen vegetation communities were identified and mapped, the most widespread being Maireana species low open-shrubland, Acacia victoriae open-shrubland and Eucalyptus largiflorens openwoodland. The Park also contains a number of rare or threatened species and vegetation communities. One hundred and fifty years of grazing by introduced herbivores coupled with the impact of a modified hydrological regime has resulted in degradation of many of these communities.
The vegetation of Narran Lake Nature Reserve (4527 ha) in the central north of New South Wales approximately 30 km west of Cumborah (29°43', 147°29') in the Walgett Shire on the North Western Plains and the Darling River Plains Bioregion is described. Seven communities are defined based on flexible UPGMA analysis of cover-abundance scores of all vascular plant taxa. These communities are mapped based on ground truthing, air photo interpretation and geological substrate. All communities are simple in structure being primarily woodlands, shrublands and herbfields. Communities are: 1) Mixed Low Woodlands, 2) Mulga Low Woodlands, 3) Triodia Hummock Grasslands, 4) Chenopod Low Open Shrublands, 5) Ephemeral Herbfields, 6) Riparian Open Forests, and 7) Lignum Shrubby Thickets. A total of 325 taxa were recorded including two species listed under the NSW Threatened Species Conservation Act (1995), Lepidium monoplocoides and Goodenia macbarroni. An additional 11 species are considered to be at their geographic limit or disjunct in their distribution; 11% are exotic in origin.
Clearing of native woody vegetation in the New South Wales northern wheatbelt was mapped for the period 1985–2000. The study area comprises the Moree 1:250,000 scale map sheet and portions of adjacent map sheets. Unpublished draft mapping of native woody vegetation types, based on 1985 aerial photography and a large set of floristic data from field surveys, was used as a baseline for this study. Mapping of clearing was carried out by intensive visual interpretation of Landsat TM satellite imagery. Systematic validation, which compared the satellite interpretation to low-level aerial photography at randomly allocated point locations, showed that the method was highly accurate in detecting vegetation clearing including in the open woodlands and shrublands that characterise much of the study area. Comparisons with previously published mapping of statewide clearing patterns, based on an automated classification of Landsat TM imagery, showed that our intensive visual interpretation detected substantially more clearing. Average annual clearing rates were 8 times higher that those derived from the previous mapping.
Results of the study show that substantial clearing of native woody vegetation is continuing in the northern wheatbelt. Over 110,000 ha of native woody vegetation were cleared between 1985 and 2000. Clearing rates were highest in the four year monitoring period that preceded the introduction of the Native Vegetation Conservation Act. The subsequent two year monitoring period saw substantially lower clearing rates, though further monitoring is needed to determine if this trend will continue. An analysis of spatial patterns highlighted continued high rates of loss in the most depleted parts of the study area. Results for individual vegetation types indicate that regrowth open shrublands and woodlands and Coolabah (Eucalyptus coolabah) dominated woodlands were the most heavily cleared.
Senecio garlandii F. Muell. ex Belcher (Asteraceae) is a perennial subshrub found mainly on rocky outcrops in the South Western Slopes, New South Wales. It is listed as vulnerable in state, national and international listings. An assessment of its conservation status found i) Senecio garlandii has been recorded from about ten localities, ii) it has a relatively large (225 km) north to south distribution from Temora, NSW to Chiltern, Vic., iii) most populations were either within the reserve system (Ulandra, The Rock, Table Top Nature Reserves) or in areas managed for conservation, iv) large populations (> 30,000 individuals) were recorded at The Rock and Table Top Nature Reserves, v) the species appeared capable of regenerating in both the absence and presence of fire, and vi) the populations did not appear to be under direct threat.
However, the known localities were highly disjunct and only three localities had substantiated recordings of large populations, while others had very small populations (e.g. < 200 individuals at Ulandra Nature Reserve). In addition, the species was largely restricted to rocky outcrops and on these it was generally restricted to the upper parts of the east- to south-facing talus slopes, often immediately below cliff lines (a small area of occupancy). Application of the IUCN red list criteria would indicate that Senecio garlandii should not be classified as vulnerable. Monitoring is needed to determine whether the populations are in decline or otherwise.
As a consequence of vegetation survey carried out in sandstone environments of the upper Hunter Valley over recent years, a number of new populations of significant plant species have been recorded. The opportunity is taken here to document some of these finds, and also to suggest some revisions to the current conservation risk codes. Twenty-three species are discussed: Acacia bulgaensis, Angophora euryphylla, Callitris rhomboidea, Banksia penicillata, Cynanchum elegans, Eucalyptus aenea, Eucalyptus dealbata, Eucalyptus fergusonii subsp. dorsiventralis, Eucalyptus nubila, Eucalyptus prominula, Gonocarpus longifolius, Grevillea johnsonii, Grevillea montana, Melaleuca groveana, Pomaderris bodalla, Pomaderris brunnea, Pomaderris precaria, Pomaderris queenslandica, Pomaderris reperta, Pomaderris sericea, Prostanthera cryptandroides subsp. cryptandroides, Prostanthera hindii, and Rulingia procumbens. Voucher specimens have been lodged for new populations of all taxa (except some populations of Cynanchum elegans) at State herbaria.
Kinchega National Park reserves significant stands of Eucalyptus largiflorens open woodland on the Darling River floodplain, low open Maireana pyramidata shrubland and Casuarina pauper/Alectryon oleifolius open woodland on dune systems. We identify four key issues for the conservation of flora in Kinchega National Park, western NSW. These are:
1) There is an urgent need to initiate regeneration in a number of long-lived perennial trees and shrubs. Failure to do so will lead to local population declines and extinction in a number of species. Reduction in grazing impacts of rabbits and goats is needed. Some degree of rabbit control has been achieved over the last few years through a combination of the effects of the rabbit calicivirus disease (RCD) and an extensive rabbit control program for the reserve.
2) The need to initiate a water plan of management for the reserve to overcome the problem of changes in water flows, flood periodicity and flood magnitude that have occurred in response to water regulation activities on the Darling River.
3) Management of several threatened species and ecological communities on the reserve, in particular the nationally vulnerable species Acacia carneorum and Solanum karsense. Kinchega NP is the only conservation reserve containing populations of these species and these populations are significant for both species.
4) Management of weeds, in particular those with bird-dispersed fruits as these species have the potential to become severe problems on the park.
Other issues that are likely to be significant in the future are salinity impacts and the interaction between grazing pressure, regeneration and climate change.
Australian subtropical rainforests and plant populations have become increasingly fragmented since European settlement. Managing relict populations and remnants within the landscape matrix is dependent upon our understanding of plant reproductive biology. The incidence of autogamous self-compatibility and dioecy was investigated in subtropical rainforests, near Taree, in the Manning Valley (northern New South Wales). The proportion of dioecious species in rainforests of the region is high (~17%), but varies among sites. The potential for hermaphroditic species to self-pollinate was examined by bagging inflorescences in the field. Of the > 30 species (in 14 families) studied, nine species exhibited high levels of selfcompatibility. These were predominantly pioneer and edge species, but other pioneer species were self-incompatible. Different behaviour occurred within families. Twenty species (in 13 families) regenerated from basal coppice or root suckers following bushfire. The significance of knowledge of reproductive biology for management is discussed.
Barbula geminata C. Muell. is Barbula crinita K.F. Schultz; Barbula austroruralis C. Muell. is Tortula antarctica (Hampe) Wils. in Hook. f.; Hymenostomum olivaceum C. Muell. ex Geheeb is Weissia controversa Hedw.; Hymenostomum sullivanii C. Muell. ex Geheeb is Weissia patula (Knight) A.J. Fife. Furthermore, comments are given on several nomina nuda.
Book Review
(2001)
This book is absolutely unique in several respects. There exists bryological glossaries, usually in bryophyte floras. Most have no figures to illustrate the terms, and some have few drawings. And there exists the “Glossarium Polyglottum Bryologicae” published by the Missouri Botanical Garden, which is comprehensive but lacks any figures. Everybody having held identification courses in bryology knows the problems of beginners, who does not know what to imagine under terms, which are in common use in bryology, and even explanations in a glossary can give the beginner no real idea. This book gives an enumeration and definition of thousands of terms and illustrates hundreds.
Felipponea assimilis (Müll.Hal.) O’Shea is the correct name to be used for all African collections of Felipponea, a species found in Uruguay, Brazil, Bolivia, southern and eastern Africa and the East African islands. Hypnum maritimum Müll.Hal. and Cladomnion montevidensis Müll.Hal. are new synonyms. Lectotypes are selected for Neckera assimilis Müll.Hal., Cladomnion montevidensis Müll.Hal. and Braunia peristomata Dixon in Sim & Dixon.
A number of collections from Africa identified as Phyllodon scutellifolius or Glossadelphus serpyllifolius belong to Bryocrumia vivicolor, previously known only from America and Asia. Phyllodon scutellifolius is known only from one (possibly two) collections from Madagascar, and Glossadelphus serpyllifolius is a synonym of Bryocrumia vivicolor.
Nord Kivu: c. 6 km north of Lubero, on sandy soil of tree-shaded road cutting, c. 1800m, 0º 8' S, 29º 14' E, 11 Aug 1988. C.R. Stevenson Z 78f, det. E.W. Jones (BM, & herb. C.R. Stevenson). Growing mixed with Frullania serrata, Pilotrichella, Trachypodopsis, etc. Distrib.: Annobon, Bioko, Burundi, Cameroun, Kenya, Rwanda, Sao Tome, Tanzania.
A survey of the literature and collections in the Monteverde Cloud Forest Preserve and adjacent pastureland yielded a total of 198 epiphytic bryophyte taxa (120 species of hepatics in 50 genera, 77 species of moss in 48 genera, and 1 hornwort): 178 in the primary forest, 63 in the secondary forest, and 84 in the pastureland.
The first record of a sporophyte of Muscites confertus Goeppert & Berendt described as fossil species from Baltic amber revealed that this species can be attributed to the genus Hypnodontopsis. It is very similar to the extant H. mexicana known from only two collections in Mexico and Uganda, but seems to differ in the absence of pluripapillose laminal cells. Therefore Muscites confertus is combined as new to the genus Hypnodontopsis.
Hypnum cupressiforme, Entodon macropus, Homalia glabella and Calyptothecium duplicatum are recorded as new from Dominican amber. Earlier records of Neckera spec. have to be transferred to Calyptothecium duplicatum. These records raise the total number of all mosses known from Dominican amber to 14. All mosses so far reported from Dominican amber are extant species which occur today in the Dominican Republic. This could indicate that the mossflora in the island of Hispaniola has not changed during the past 20-40 Mio years, but also falsifications of fossils in amber have to be taken into account, which can be suspected from the quality of some of the specimens.
Six altitudinal transects through temperate rain forests were studied at different latitudes in the South and North Island of New Zealand with respect to species numbers of bryophytes, cover and phytomass of epiphytic bryophytes, composition of life forms and ratio liverworts : mosses. Phytodiversity of bryophytes is almost constant from the lowlands to the high montane belt but decreases in the subalpine belt. Similarly, phytomass and cover increase with elevation but decrease in the subalpine belt. The percentage of liverworts increases accordingly and can reach maxima of 80-90%. The most significant life forms are tails and wefts characteristic for hyperhygric conditions, pendents for cloud belts and cushions for subalpine belts. The altitudinal gradient is much stronger then the latitudinal gradient, that means the differences between the elevations within a transect are more important than the differences between the transects. They are attributed to the humidity. The temperate rain forests of New Zealand have similar bryological characteristics as the tropical rain forests in equatorial latitudes in 2000 – 3000 m altitude but differ in the drier subalpine belt and higher phytomass.
The altitudina l distribution of selected species of epiphyllous Lejeuneaceae shows 6 groups (table 1 and 2): I (only lower than 500 m) Cololejeunea setiloba; II (1-1600m) Aphanolejeunea costaricensis, A. moralesiae, Cololejeunea cardiocarpa, C. guadelupensis, C. linopteroides, C. obliqua, C. papillifera, C. standleyi, Colura verdoornii, Cyclolejeunea chitonia, C. peruviana, Diplasiolejeunea brunnea, Microlejeunea epiphylla, Rectolejeunea berteroana, R. cf. emarginuliflora, Stictolejeunea squamata; III (1-3000m) Aphanolejeunea angustissima, Colura tortifolia, Diplasiolejeunea cavifolia, D. pellucida, Drepanolejeunea inchoata, Dr. lichenicola, Lejeunea laetevirens, Odontolejeunea lunulata; IV (only 500-1600m) Aphanolejeunea cingens, A. longifolia, A. pustulosa, Cyclolejeunea accedens, C. convexistipa, Diplasiolejeunea grolleana, D. unidentata, Harpalejeunea uncinata, Lejeunea filipes, Odontolejeunea decemdentata; V (500-3000m) Anoplolejeunea conferta, Aphanolejeunea crenata, A. ephemeroides, Colura tenuicornis, Diplasiolejeunea alata, Drepanolejeunea infundibulata, Dr. mosenii, Lejeunea flava, Omphalanthus filiformis; VI (only above 1600-3000m) Aphanolejeunea camillii, Cololejeunea fefeana, Diplasiolejeunea costaricensis sp.nov., D. involuta.
Taxonomic results of the Bryotrop expedition to Zaire and Rwanda : 33., Splachnaceae, Tayloria
(2001)
A revision of the african species of the genus has been published by Koponen & Weber (1972). Out of eight African species named by O´Shea (1995) two quite common ones have been found on the BRYOTROP III Expedition. Abbreviations: KB = Kahuzi-Biega National Park, Zaire, Ny = Nyungwe Forest, Rwanda, Ka = Mt. Karisimbi, Rwanda. For the descriptions of the collecting sites see Fischer (1993).
On the distribution of Astrobunus laevipes CANESTRINI, 1872 (Arachnida: Opiliones) in Central Europe
(2001)
Published data and unpublished communications show that the range of Astrobunus laevipes in Central Europe is much larger than previously believed. The present review extends the list of records to the German states of Baden-Württemberg, Hessia, Rhineland Palatinate, Bavaria, Northrhine-Westfalia, Saxony, and Lower Saxony and provides a map of the present distribution in Germany. Furthermore, it lists new findings of A. laevipes in the Czech Republic and Hungary (Rakaca/Serehat Valley). Records of A. laevipes in Austria are not included in this review.
Representatives of Oonopidae are tiny spiders, usually of a pale colour, with 6 oval eyes. Systematically, they belong to Dysderoidea, which include about 120 genera (CODDINGTON & LEVI 1991), but Oonopidae, alone, include 51 genera and more than 70 species (PLATNICK 1989). They are distributed all over the world, except for Antarctica, but most of the species come from the tropics. In Europe, there are 6 genera of oonopid spiders, represented by about 20 species (PLATNICK 1989). But only 6 species have been known from the Central Europe until recently (NENTWIG 1991). In Slovakia, only 2 species of oonopid spiders, Oonops domesticus Dalmas, 1916 and Triaeris stenaspis Simon, 1891, have been recorded so far (GAJDOS et al. 1999).
Definition: Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are both cholestatic liver diseases. A common feature of these disorders is the accumulation of bile acids in the liver and blood, presumably because of decreased biliary secretion and reduced bile flow.
Etiology: Etiology and pathogenesis of PBC and PSC are still unknown. PBC is considered to be an autoimmune disease. Immunological mechanisms may also be involved in PSC since there is an association with ulcerative colitis and autoantibodies can be detected. Furthermore, genetic factors seem to play an important role in both diseases.
Therapy: Since the pathogenesis of both diseases is unclear, there is no definite causal treatment. However, ursodeoxycholic acid (UDCA) was shown to be highly effective. Other drugs which can be used alone or in combination with UDCA are promising and might further improve the outcome of the diseases.
Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels. Angiogenesis is regulated by several endogenous stimulators and inhibitors of endothelial cell migration, proliferation and tube formation. Under physiological conditions these mediators of endothelial cell growth are in balance and vessel growth is limited. In fact, within the angiogenic balance endothelial cell turnover is sufficient to maintain a functional vascular wall but does not allow vessel growth. Tumor growth an progression has successfully been correlated to the serum concentration of angiogenic mediators. Furthermore, the vascular density of tumor tissues could be correlated to the clinical course of the disease in several tumor entities. Within the last years several new mediators of endothelial cell growth have been isolated e.g. angiopoietin 1, angiopoietin 2, midkine, pleiotropin, leptin and maspin. In this review we discuss the mechanisms leading to tumor angiogenesis and describe some of the newer mediators of endothelial cell stimulation and inhibition.
In view of the tremendous success of Victor Klemperer's diaries testimoning his personal experience as a Jew in Nazi Germany, this article discusses the specific contribution of witness literature to the knowledge of history. During the Holocaust period, in the face of death, true historical knowledge was essentially reduced to personal experience. Klemperer's clandestine journal exposes how the collective trauma affected everybody through the daily speech patterns, dictated by the Nazis' appropriation of the German language. In this memory of Alltagsgeschichte as a critical history of language can be seen the specific contribution of Literature of testimony. The function of Klemperers chronicle of 'Lingua Tertii Imperii' to develop the readers linguistic sensitivity, in order to enable them to reappropriate their language.
In the present context of the triumph of capitalism over real socialism, this article points out that, despite their ideological differences, both systems are bound to the same conception of history-as-progress. In contrast, it recalls Walter Benjamin's philosophy of history, marked by the critique of progress in the name of a revolutionary time, which interrupts history's chronological continuum. Benjamin's perspective is used to study the conflict of temporalities among the Soviet artists in the two decades after the October Revolution: on the one hand, the anarchic, autonomous and critical time of interruption – which is the time of avant-gade –, on the other hand, the synchronization with the ideas of a progressive time as ordered by the Communist Patty; this is the time of vanguard, whose capitalist Counterpart is fashion.
Taxonomy, phylogeny, and biogeography of the genus Asydates Casey (Insecta: Coleoptera: Melyridae)
(2001)
The genus Asydates Casey (Coleoptera: Melyridae) is revised, containing three species from Arizona and California: A. explanatus Casey; A. inyoensis (Blaisdell), new combination; and A. rufiuentris Casey. The monotypic genus Pseudasydates Blaisdell is placed in synonymy with Asydates Casey, syn. nov., and Asydates puncticeps Blaisdell is placed in synonymy with Asydates explanatus Casey, syn. nov. A key separating adults of Asydates species is provided, and the results of a computerized cladistic analysis of Asydates species are presented. GIS mapping of Asydates species distributions indicates that these species are nearly allopatric, with A. explanatus found in the lower Colorado River basin and adjacent deserts, A. inyoensis restricted to the Inyo and White Mountains, and A. rufiuentris found in the coastal plain and coastal mountains near Santa Barbara. Geographic hypotheses of character evolution within Asydates are developed by combining the results of cladistic analysis and GIS mapping.
Information on the immature stages of Australasian Tabanidae found in published literature dealt with only 17 species, all so far known only from Australia and none representing the genus Chrysops Meigen. Two of the four Australasian species of Chrysops are found on the island of New Guinea, and both, C. albicinctus Wulp and C. australis Ricardo, are described and illustrated.
The cholevine beetles inhabiting burrows of Geomys and Thomomys pocket gophers (Rodentia: Geomyidae) are reviewed. Catops geomysi n. sp. and Ptomaphagus geomysi n. sp. are described. Both of these species and Ptomaphagus schwarzi Hatch appear to be regular and obligate inhabitants of Geomys burrows b~t are not host specific. Nemadus hornii Hatch, Sciodrepoides watsoni horn ian us (Blanchard), Catops s~mplex Say, Ptomaphagus cavernicola Schwarz, Ptomaphagus consobrinus (LeConte), Ptomaphagus fisus Horn, and Ptomaphagus texanus Horn were less frequently collected and are probably facultative inhabitants of Geomys burrows, as well as nests or dens of other small mammals. Ptomaphagus nevadicus Horn is an inhabitant of ~)Urrows of Thomomys pocket gophers in western North America. A key to the species of Ptomaphagus III the southeastern Gulf Coastal Plain, from non-cave habitats, is provided to aid in their identification.
A list of 35 scale insects collected from 72 ornamental plant species in Sao Carlos, Sao Paulo, Brazil is provided. Regarding host specificity, 30 scale insects were polyphagous, 4 oligophagous, and 1 monophagous. A total of 102 coccoid/plant associations are recorded, 29 of which are new host records for the species; 60 are new host records for the species in Brazil. Pulvinaria urbicola Cockerell, 1893 (Coccidae), Phenacoccus similis Granara de Willink, 1983 (Pseudococcidae), and Orthezia molinarii (Morrison, 1952) (Ortheziidae) are recorded for the first time in Brazil. In addition, we describe the injury caused by scale insects on ornamental plants.
This paper reports on the scarab beetles collected during a survey of nonparasitic arthopods living in burrows of the southeastern pocket gopher (Geomys pinetus Rafinesque, Geomyidae). Three new species are described: Aphodius bakeri, A. baileyi and A. gambrinus. A key to species of Aphodius occurring in these burrows is presented. Distributional data is provided for species of Aphodius and one species of Euphoria
occurring in this microhabitat. Aspects of life histories of burrow inhabiting insects are speculated upon.
This study is a contribution to the knowledge of the weevil species present in the State of Guanajuato, Mexico. During this study, 73 genera and 125 species were identified. The subfamilies best represented were Baridinae, Curculioninae and Entiminae with 24, 24 and 23 species, respectively. The genera best represented were Geraeus and Anthonomus with seven species and Conotrachelus with six, Of the 125 species identified, 18 represent new country records. Of the weevil species found in Guanajuato, 53.7% are Neotropical, 26% are Nearctic, 18.4% are cosmopolitan, and the remainder (1.9%) previously were known only from the West Indies.
Records and descriptions are given for the 10 known species in six genera of Bruchidae from the Archipelago including Sennius falcatus New Species and Acanthoscelides rossi New Species. Amblycerus (Spermophagus) insulamm (Blair) is synonymized with Amblycems piurae (Pierce), New Synonymy. Five of the species herein treated are new records for the Archipelago, and 8 of the 10 are also known from mainland South America, principally Ecuador.
Texas has one of the most diverse orthopteroid assemblages of any state in the United States, reflecting the varied habitats found in the state. Three hundred and eighty-nine species and 78 subspecies of orthopteroid insects (Blattodea, Mantodea, Phasmatodea, and Orthoptera) have published records for the state of Texas. This is the first such comprehensive checklist for Texas and should aid future work on these groups in this area.
New nomenclatural changes are presented for selected North American mordellid beetles (Coleoptera: Mordellidae). The following five genera are newly recorded fi.·om the United States: Mordellaria Ermisch 1950, Falsomordellistena Ermisch 1941, Mordellina Schilsky 1908, Mordellochroa Emery 1876, and
Pseudotolida Ermisch 1950. The following species are transferred from Tomoxia and represent new combinations: Mordellaria borealis (LeConte 1862), Mordellaria fascifera (LeConte 1878), Mordellaria latipalpis (Ray 1946), Mordellaria serval (Say 1835), and Mordellaria undulata (Melsheimer 1845). The following species are transferred fi.·om Mordellistena and represent new combinations: Falsomordellistena hebraica (LeConte 1862) and Falsomordellistena pubescens (Fabricius 1798); Mordellina blatchleyi (Liljeblad 1945), Mordellina pilosella (Ray 1947), Mordellina pustulata (Melsheimer 1845), Mordellina ustulata (LeConte 1862), and Mordellina wichhami (Liljeblad 1945); Mordellochroa scapularis (Say 1824); Pseudotolida
arida (LeConte 1862), Pseudotolida hnausi (Liljeblad 1945), and Pseudotolida lutea (Melsheimer 1845). Mordellina ustulata (LeConte 1862) represents a return to species rank after being treated as a subspecies of Mordellistena andreae LeConte 1862. There are a total of 17 genera of Mordellidae in America north of Mexico.
A new key is presented to separate adults of the four currently-recognized species of the genus Cradytes Casey (Insecta: Coleoptera: Melyridae): C. longicollis Casey, C. serricollis (LeConte), C. serrulatus . (LeConte), and C. ursinus Blaisdell. The inaccurate statements in an earlier key to species of Cradytes are discussed.
Hydrocolus heggiensis : a new species from Georgia and South Carolina (Coleoptera: Dytiscidae)
(2001)
Hydrocolus heggiensis, a new species of predacious water beetle, is described from granite monadnocks in Georgia and one location in South Carolina. It most closely resembles H. stagnalis (Gemminger and Harold) but differs in range, genitalia, and elytral punctation. Photographs, drawings, and an interpolation of the new species into existing keys are given.
Epimechus curvipes Dietz is designated as type species of the genus Epimechus Dietz. Ten additional species from western North America, including four new species, are assigned to the genus: E. aemulus Fall; E. flavirostris Fall; E. mimicus Dietz; E. adspersus Dietz; E. mobilis Fall; E. nevadicus Dietz; E. molina, new species (Arizona, Baja California Norte); E. combustus, new species (Arizona, New Mexico, Utah); E. signum, new species (Arizona, Coahuila, Colorado, New Mexico, Saskatchewan, Texas, Utah) and E. hesperius, new species (Arizona, California, Colorado, Guanajuato, Idaho, Nevada, New Mexico, Nuevo Leon, South Dakota, Texas, Utah, Wyoming). These are distinguished from other Anthonomini by the short, simple tarsal claws. The names Epimeclws modicus Fall, E. soriculus Dietz, and E. nanulus Fall are placed in new synonymy under E. curvipes. Lectotypes are designated for E. adspersus and E. nevadicus. Two species formerly in Epimechus are transferred the subgenus Cnemocyllus Dietz in Anthonomus Germar: E. arenicolor Fall as Anthonomus arenicolor (Fall), new combination, and E. canoides Fall as Anthonomus canoides (Fall), new combination. Adults of species of Epimechus have been collected on plants in the genera Baccharis, Chrysothamnus, Ericameria, Gutierrezia, Haplopappus, Senecio and Tetradymia (all Asteraceae).
Rhyssa neotropicae n. sp. is the first Rhyssa to be recorded from the New World tropics, where it was collected in cloud forest at 1800 m on Monte Uyuca near Zamorano, Honduras. It is closely related to the Nearctic R. hoferi Rohwer and R. howdenorum Townes but differs from all other Rhyssa by its complexly yellow and black marked head and body, whose color pattern mimics that of aggressive social vespid wasps (Agelaia) which occur in the same habitat. Rhyssa howdenorum Townes is recorded for the first time from Florida and Oklahoma. The genus Rhyssella, previously unknown in Florida, is represented in that state by R. perfulua n. sp., distinctive in its mostly orange brown coloration, and by R. humida (Say), a black and white species with fulvous on the thoracic pleura and propodeum.
A new family Coryphoridae is proposed in the superfamily Ephemerelloidea for the monotypic genus Coryphorus. Characters that distinguish Coryphoridae from all other Ephemerelloidea are discussed. The male imago, male subimago, female imago, and egg of Coryphorus aquilus Peters are described for the first time.
Based on adult character states, a key is provided to the seven known species of Oreodicastes Maindron 1905 (type species Oxyglossus subcyaneus Chaudoir 1843). Two new species (with type locality) are described: O. virginia (Fa zenda dos Campos, Virginia, state of Minas Gerais, Brazil) and O. zikani (Macieiras, Itatiaia, state of Rio de Janeiro, Brazil).