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To investigate the formation and the propagation of relativistic shock waves in viscous gluon matter we solve the relativistic Riemann problem using a microscopic parton cascade. We demonstrate the transition from ideal to viscous shock waves by varying the shear viscosity to entropy density ratio n/s. Furthermore we compare our results with those obtained by solving the relativistic causal dissipative fluid equations of Israel and Stewart (IS), in order to show the validity of the IS hydrodynamics. Employing the parton cascade we also investigate the formation of Mach shocks induced by a high-energy gluon traversing viscous gluon matter. For n/s = 0.08 a Mach cone structure is observed, whereas the signal smears out for n/s >=0.32.
Meeting Abstract : Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie e.V. (GAA). 17. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie. Osnabrück, 25.-26.11.2010.
ntroduction: Several drugs require dose adjustment in patients with impaired renal function, which however, often goes undetected. Serum creatinine may be normal in patients while renal function is already reduced. The estimated GFR (eGFR) allows a more precise evaluation of the renal function. This study was carried out in a group practice for family medicine, in Frankfurt/ Main, Germany. The exploration aimed at investigating if patients with renal insufficiency were recognised and if their prescriptions were appropriate in terms of dose adjustment or contra-indications.
Methods: In patients (>65yrs) with renal insufficiency (creatinine clearance <60 ml/min), their prescribed medication was retrospectively explored (Observation period 1.1.2008 to 1.4.2009). The Cockroft-Gault formula was used as estimate for the eGFR, using a creatinine value from the patient’s charts. In 90 patients, a second eGFR could be estimated from a second creatinine value obtained within 3-6 months. The recommended dose of each prescription in the SmPC (Fachinformation“) was compared to the dose that had been actually prescribed.
Results: Out of 232 consecutively patients >65 yrs, 102 had an eGFR <60 ml/min, 16 of these had an eGFR <30 ml/min. The eGFR was closely correlated (r2=0.81) with an independent second eGFR. Out of these 102 patients, 48 had a serum creatinine level within the normal range. Renal adjustment was required in 263 of a total of 613 prescriptions. 72 prescriptions in a total of 45 patients were not appropriately adjusted (32) or prescribed despite a contraindication (40). For chronic prescriptions, metformin, ramipril, enalapril, HCTZ, and spironolactone accounted for 70% of inappropriate dosing; the magnitude of misdosing was 1.5 to 4 fold (median 2). 9 temporary prescriptions (of a total of 60 prescriptions) in 8 patients were not adjusted (cefuroxim, cefpodoxim, levofloxacin). We could not prove that patients with normal serum creatinine had a higher rate of inappropriate dosing than those with already elevated creatinine.
Discussion and conclusion: In this GP practice, we have demonstrated a considerable prevalence of inappropriate dosing in patients with impaired renal function. It remains to be elucidated whether surveillance of appropriate dosing in renal impairment can be optimized e.g. with CPOE.
This paper presents a descriptive overview and formal analysis of the use of pronominal clitics for realizing various types of arguments in Persian, with particular emphasis on object clitics in the verbal domain. We argue that pronominal clitics behave more like suffixes than independent syntactic elements; in cases where they take syntactic scope over an NP or a PP, they must be phrasal affixes. We propose an HPSG analysis to account for the morphosyntactic aspects of verbal suffixation of object clitics, possessive clitics, preverbal object clitics, and clitic doubling constructions. Finally, we explore extensions of the analysis to periphrastic verb forms, and we compare our proposals for Persian to previous HPSG work on clitic phenomena in other languages.
This work focuses on the syntax and semantics of the expression vice versa, and shows that its syntactic distribution is much more flexible than semantically related expressions. Although vice versa usually appears in clausal coordinate environments, it can in principle occur in any other type of construction. Second, it can occur as an embedded verb phrase or even as a noun phrase, rather than as an adjunct. This suggests that vice versa is a propositional anaphor that corresponds to a converse of a propositional antecedent. Finally, although the predicates singled out to be interchanged are usually nominal, they can in fact be of virtually any part of speech. I argue that a possible account of the interpretation of vice versa lies at the interface between logical form (with rich decompositional lexical semantics along the lines of Pustejovsky (1995)), and pragmatics (drawing from independent work by Hobbs (1990) and Kehler (2002)).
ecently, pertussis has become a problem also in the adult population, with incidences even higher than in children. Pediatric health care workers (HCWs) are an important source of transmission, exposing very young and immunocompromised patients to an increased risk of potentially severe pertussis infections. Encouraging HCWs to get vaccinated can play a vital role in stopping the transmission of pertussis, thereby reducing institutional outbreaks.
In Germany, HCWs come up with all sorts of reasons for not getting pertussis vaccination. This study was meant to provide information in order to better understand the backgrounds of these attitudes.
A survey was conducted at the children's university hospital in Frankfurt, using an anonymous questionnaire. Survey results were used to design an intervention to increase the immunization rate of staff. Disappointingly, our efforts to increase the acceptance of the immunization program by providing information in advance were not yet satisfying.
Misconception about pertussis vaccination was prevalent especially among nursing staff. The main reasons for non-compliance included: unawareness of an own risk of infection, the belief that pertussis is not a serious illness, fear of side effects, the belief that the pertussis vaccine might trigger the pertussis disease itself, and skepticism about the efficacy of the pertussis vaccination.
We present results of lattice QCD simulations with mass-degenerate up and down and mass-split strange and charm (Nf = 2+1+1) dynamical quarks using Wilson twisted mass fermions at maximal twist. The tuning of the strange and charm quark masses is performed at three values of the lattice spacing a ~ 0:06 fm, a ~ 0:08 fm and a ~ 0:09 fm with lattice sizes ranging from L ~ 1:9 fm to L ~ 3:9 fm. We perform a preliminary study of SU(2) chiral perturbation theory by combining our lattice data from these three values of the lattice spacing.
Based on the notion of a lexicon with default inheritance, I address the problem of how to provide a template for lexical representations that allows us to capture the relatedness between inflected word forms and canonically derived lexemes within a broadly realizational-inferential model of morphology. To achieve this we need to be able to represent a whole host of intermediate types of lexical relatedness that are much less frequently discussed in the literature. These include transpositions such as deverbal participles, in which a word's morphosyntactic class changes (e.g. verb ⇒ adjective) but no semantic predicate is added to the semantic representation and the derived word remains, in an important sense, a "form" of the base lexeme (e.g. the 'present participle form of the verb'). I propose a model in which morphological properties are inherited by default from syntactic properties and syntactic properties are inherited from semantic properties, such as ontological category (the Default Cascade). Relatedness is defined in terms of a Generalized Paradigm Function (perhaps in reality a relation), a generalization of the Paradigm Function of Paradigm Function Morphology (Stump 2001). The GPF has four components which deliver respectively specifications of a morphological form, syntactic properties, semantic representation and a lexemic index (LI) unique to each individuated lexeme in the lexicon. In principle, therefore, the same function delivers derived lexemes as inflected forms. In order to ensure that a newly derived lexeme of a distinct word class can be inflected I assume two additional principles. First, I assume an Inflectional Specifiability Principle, which states that the form component of the GPF (which defines inflected word forms of a lexeme) is dependent on the specification of the lexeme's morpholexical signature, a declaration of the properties that the lexeme is obliged to inflect for (defined by default on the basis of morpholexical class). I then propose a Category Erasure Principle, which states that 'lower' attributes are erased when the GPF introduces a non-trivial change to a 'higher' attribute (e.g. a change to the semantic representation entails erasure of syntactic and morphological information). The required information is then provided by the Default Cascade, unless overridden by specific declarations in the GPF. I show how this model can account for a variety of intermediate types of relatedness which cannot easily be treated as either inflection or derivation, and conclude with a detailed illustration of how the system applies to a particularly interesting type of transposition in the Samoyedic language Sel'kup, in which a noun is transposed to a similitudinal adjective whose form is in paradigmatic opposition to case-marked noun forms, and which is therefore a kind of inflection.
Korean comparative constructions: A constraint-based approach and computational implementation
(2010)
The complexity of comparative constructions in each language has given challenges to both theoretical and computational analyses. This paper first identifies types of comparative constructions in Korean and discusses their main grammatical properties. It then builds a syntactic parser couched upon the typed feature structure grammar, HPSG and proposes a context-dependent interpretation for the comparison. To check the feasibility of the proposed analysis, we have implemented the grammar into the existing Korean Resource Grammar. The results show us that the grammar we have developed here is feasible enough to parse Korean comparative sentences and yield proper semantic representations though further development is needed for a finer model for contextual information.
We describe an empirical method to explore and contrast the roles of default and principal part information in the differentiation of inflectional classes. We use an unsupervised machine learning method to classify Russian nouns into inflectional classes, first with full paradigm information, and then with particular types of information removed. When we remove default information, shared across classes, we expect there to be little effect on the classification. In contrast when we remove principal part information we expect there to be a more detrimental effect on classification performance. Our data set consists of paradigm listings of the 80 most frequent Russian nouns, generated from a formal theory which allows us to distinguish default and principal part information. Our results show that removal of forms classified as principal parts has a more detrimental effect on the classification than removal of default information. However, we also find that there are differences within the defaults and principal parts, and we suggest that these may in part be attributable to stress patterns.