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This article deals with the literary depiction of Prince Felix Lichnowsky viewed through the lens of the Czech translation of the verse epic Atta Troll. The translation was published in 1953 and is linked to the translation work of Eduard Petiška. The aim of the study is to illuminate the correspondences or differences arising from the comparison of the original version with its translation.
Die Frage ist, ob Blumenbergs explizite Überlegungen zum Phänomen der Epochenschwelle - vor allem in der 'Legitimität der Neuzeit' - sich auch in seinen anderen begriffs- und metapherngeschichtlichen Studien niederschlagen bzw. in welchem Verhältnis beide Theorieelemente zueinander stehen. Dieser Frage widmen sich die folgenden Anmerkungen. Sie versuchen beide Bereiche in Blumenbergs Denken aufeinander zu beziehen, ihre Kohärenz zu untersuchen und sie in eine produktive Spannung miteinander zu bringen.
Background: Research has implicated that changes in zinc (Zn) metabolism may be associated with the biological underpinnings of eating disorders, in particular anorexia nervosa. However, to date research on the role of Zn in patients with bulimia nervosa (BN) is scarce.
Objective: We aimed to explore serum Zn concentrations in young patients with BN, with a focus on the stage of the disorder, comparing acutely ill and recovered patients with BN with healthy controls.
Methods: Serum Zn concentrations were obtained from healthy controls and from acutely ill and remitted young patients with BN. Mean duration of remission was 4.0±3.5 years.
Results: Remitted patients showed elevated serum Zn concentrations when compared to controls (Cohen’s d=2.022), but concentrations were still in the normal range. Acutely ill patients also had higher serum Zn levels when compared to controls (all values still being within the reference range, Cohen’s d=0.882). There was no difference between acutely ill and remitted patients with BN in serum Zn concentrations. Of note, remitted patients had a significantly higher body weight when compared to the other two groups. Overall, there were no significant differences in dietary preferences with regard to Zn containing foods between the groups.
Conclusion: The present study provides preliminary evidence that the underlying factors for changes in Zn serum concentrations in young patients with BN do not vary with regard to the stage of illness (acute versus remitted BN). Further prospective research is needed in order to disentangle the possible interplay between serum Zn status and bulimic eating behaviors.
Aus der Distanz von beinahe zwei Dekaden werden der Literaturstreit und die daran anschließende Stasi-Debatte in dem selbsterkundenden Buch Stadt der Engel als Gewaltdiskurs wahrgenommen und ambivalent reflektiert. Die erzählerische Reflexion dieses Diskurses ist allerdings in ein Geflecht von Gewaltnarrativen eingebettet, das nur schwer zu entwirrenund zu entschlüsseln ist. Der vielschichtige Text ist jedoch nicht auf die literarische Vergegenwärtigung der strukturellen Gewalt im DDR-Regime oder der symbolischen Gewalt in den medialen Kontroversen zu reduzieren, ebenso wäre die Einschränkung auf die quälende Selbstbefragung der Erzählerin im Zusammenhang mit ihren in Vergessenheit geratenen Stasi-Kontakten und damit der eigenen Verstrickung in die Gewaltstrukturen eine unzulässige Vereinfachung.
Lieblingsbild
(2017)
Dieses Bild ist wichtig, weil wir daran verstanden haben, wie in der Zelle fehlerhaftes Spleißen verhindert wird. Dazu muss man wissen, dass unsere Gene sich aus Exons und dazwischenliegenden Introns zusammensetzen. Während des Spleißens werden die Introns entfernt und die Exons in ein reifes Transkript zusammengefügt, das dann für ein Protein kodiert. Allerdings gibt es innerhalb der Introns viele Bereiche, die einem Exon sehr ähnlich sehen. Werden diese sogenannten "PseudoExons" fälschlicherweise während des Spleißprozesses erkannt und in das reife Transkript eingebaut, kann das fatale Folgen für das kodierte Protein und oft die gesamte Zelle haben. ...
Fossil dental remains are an archive of unique information for paleobiological studies. Computed microtomography based on X-ray microfocus sources (X-μCT) and Synchrotron Radiation (SR-μCT) allow subtle quantification at the micron and sub-micron scale of the meso- and microstructural signature imprinted in the mineralized tissues, such as enamel and dentine, through high-resolution “virtual histology”. Nonetheless, depending on the degree of alterations undergone during fossilization, X-ray analyses of tooth tissues do not always provide distinct imaging contrasts, thus preventing the extraction of essential morphological and anatomical details. We illustrate here by three examples the successful application of neutron microtomography (n-μCT) in cases where X-rays have previously failed to deliver contrasts between dental tissues of fossilized specimen.
Hypoxia-induced miR-210 displays a pro-survival, cytoprotective and pro-angiogenic role in several in vitro systems. In vivo, we previously found that miR-210 inhibition increases ischemic damage. Here we describe the generation of a versatile transgenic mouse model allowing the evaluation of miR-210 therapeutic potential in ischemic cardiovascular diseases. We generated a Tet-On miR-210 transgenic mouse strain (TG-210) by targeted transgenesis in the ROSA26 locus. To functionally validate miR-210 transgenic mice, hindlimb ischemia was induced by femoral artery dissection. Blood perfusion was evaluated by power Doppler while tissue damage and inflammation were assessed by histological evaluation. We found that miR-210 levels were rapidly increased in TG-210 mice upon doxycycline administration. miR-210 overexpression was maintained over time and remained within physiological levels in multiple tissues. When hindlimb ischemia was induced, miR-210 overexpression protected from both muscular and vascular ischemic damage, decreased inflammatory cells density and allowed to maintain a better calf perfusion. In conclusion, we generated and functionally validated a miR-210 transgenic mouse model. Albeit validated in the context of a specific cardiovascular ischemic disease, miR-210 transgenic mice may also represent a useful model to assess the function of miR-210 in other physio-pathological conditions.
The aim of this article is to compare migration as an intercultural confrontation and translation as a phenomenon creating a "Third Space" for cultural negotiation. In this frame it analyses what role interculturality plays in both areas and how these areas mutually reshape the other.
The study deals with how the deconstructive approaches that have triggered a new understanding in the field influence translation. In this context, the concept of interculturality brought both by translation and migration, should not be considered as a medium for harmonization and assimilation, but as a means of respect to the foreign that challenges the asymmetries and dominance between the powers. In this sense, the study will demonstrate how intercultural migration and translation enabling constructive and productive interaction can function as a dynamic potential for cultures.
Since translation and migration are two major restorative factors for intercultural communication, they create the mobility of people so of cultures which results in a reframing of the obsolete traditional perception of culture that relies on an isolated and homogenous culture model. This communication enables not only a new understanding of the other and a convergence of the cultures involved, but it also promotes a realisation of the self and its borders
Although students make a great effort to learn a foreign language, it is an undeniable fact that they have some difficulties of understanding during communication. One of the prominent reasons of this situation is their having lack of vocabulary rather than grammar knowledge. This situation also effects the motivation of students in the process of learning negatively. Especially, words that have morphological similarities, but semantically different ones cause a problem in the process of learning, which can not be overcome without getting help professionally. The morphological similarities of the words lead students fail to understand different meanings of these kinds of words. For this reason, the purpose of this study is to investigate the words which cause difficulties because of the morphological similarities for the students to learn. As the study handles the subject in this concrete perspective, it contributes to the teachers having problems in teaching aforementioned difficult words.