Filtern
Erscheinungsjahr
- 2011 (124) (entfernen)
Dokumenttyp
- Wissenschaftlicher Artikel (124) (entfernen)
Volltext vorhanden
- ja (124)
Gehört zur Bibliographie
- nein (124)
Schlagworte
- mitochondria (3)
- Hepatocellular carcinoma (2)
- Outcomes (2)
- TRAIL (2)
- Transarterial chemoembolization (2)
- apoptosis (2)
- chemotherapy (2)
- ADAM-17 (1)
- Actaea cimicifuga (1)
- Allochromatium vinosum (1)
- Alzheimer's disease (1)
- Alzheimer’s disease (1)
- Antiangiogenesis (1)
- Antiviral therapy (1)
- Aortic Valve Replacement (1)
- Attention (1)
- Autism (1)
- BCR/ABL (1)
- Black cohosh (1)
- Black cohosh induced liver injury (1)
- Bottom-up (1)
- C-clamp (1)
- CYP450 (1)
- Capsule endoscopy (1)
- Cell Adhesion (1)
- Clinical Skills (1)
- Competencies (1)
- Consensus methods (1)
- CoxVa (1)
- Crohn’s disease (1)
- Crossmodal (1)
- Cyclosporin A (1)
- Cytokines Induction (1)
- Delphi Survey (1)
- Delphie-Befragung (1)
- Directly acting antiviral agent (1)
- Drug induced liver injury (1)
- E-Learning (1)
- EET (1)
- EZ-IO® needle driver (1)
- Electroencephalography (1)
- Emergency medicine (1)
- Evaluation (1)
- Event-related potential (1)
- Fertigkeiten (1)
- Functional connectivity (1)
- Functional magnetic resonance imaging (1)
- Gene Regulation (1)
- Generalized procrustes analysis (1)
- Genome-wide association study (1)
- Genomic medicine (1)
- H1N1 (1)
- HSCT (1)
- Hemagglutination inhibition assay (1)
- Hepatitis C virus (1)
- Hepatotoxicity (1)
- Herb induced liver injury (1)
- Herbal hepatotoxicity (1)
- Highwire (1)
- Human genetics (1)
- Humangenetik (1)
- IAPs (1)
- Immunology (1)
- Immunosuppression (1)
- Independent component analysis (1)
- Individualized therapy (1)
- Inflammation (1)
- Inside-out Signaling (1)
- Integrin (1)
- Interferon-α (1)
- Interferon-λ, (1)
- Interleukin (1)
- Interleukin-22 (1)
- Intraosseous access (1)
- Klinische Fertigkeiten (1)
- Kompetenzen (1)
- Konsensus Methode (1)
- L2 (1)
- LFA-1 (1)
- Left Ventricular Mass (1)
- Lernziele (1)
- Local field potential (1)
- Lymphocyte (1)
- MCAK (1)
- MDM2 (1)
- MYCBP2 (1)
- Mgm1p (1)
- Multimedia (1)
- Multisensory (1)
- Multiset independent component analysis (1)
- Neuron (1)
- Object perception (1)
- Objectives (1)
- P600 (1)
- PAM (1)
- PHR1 (1)
- PI3K (1)
- Pain (1)
- Parkinson’s disease (1)
- Personal medicine (1)
- Phase-reset (1)
- Philadelphia Chromosome-positive leukemia (1)
- Podospora anserina (1)
- Portal (1)
- Practical skills (1)
- Praktische Fertigkeiten (1)
- Prospective randomized Analysis (1)
- Protein Translocation (1)
- SKAP1 (1)
- STDP (1)
- Schizophrenia (1)
- Sensory processing (1)
- Shunt (1)
- Single nucleotide polymorphism (1)
- Skills (1)
- Small bowel endoscopy (1)
- Sorafenib (1)
- T Cell Biology (1)
- T Cells (1)
- TIM23 (1)
- TKI (1)
- TRP Channels (1)
- TRPA1 (1)
- Thrombosis (1)
- Trafficking (1)
- Ubiquitin Ligase (1)
- Vision (1)
- acupuncture (1)
- adverse reaction (1)
- aging (1)
- anaemia (1)
- anoxygenic phototrophic sulfur bacteria (1)
- antibodies (1)
- asthma (1)
- auditory language processing (1)
- auto-structure (1)
- autovaccine (1)
- biomarker (1)
- blood transfusion (1)
- brainstem (1)
- cancer (1)
- chemoresistance (1)
- chinese medicine (1)
- chromosome instability (1)
- competitive peptide (1)
- dementia (1)
- dermatomes (1)
- dissimilatory sulfite reductase (1)
- drug resistance and invasiveness (1)
- dsr genes (1)
- e-Learning (1)
- evaluation (1)
- frontotemporal lobar degeneration (1)
- head zones (1)
- healthcare worker (1)
- hemorrhage (1)
- history of medicine (1)
- house dust mite allergy (1)
- human (1)
- hyperalgesia (1)
- i-AAA protease (1)
- image distortion (1)
- immunization (1)
- integrate and fire (1)
- kyphosis (1)
- lactate (1)
- medical education (1)
- medizinische Ausbildung (1)
- membrane protein (1)
- mitotic kinases (1)
- molecular targeted drugs (1)
- molecular targeting (1)
- multimedia (1)
- needle displacement (1)
- neurodegenerative diseases (1)
- nociceptors (1)
- non-Poissonian (1)
- novel H1N1 influenza (1)
- nutlin-3 (1)
- oligomerization (1)
- orthodeoxia (1)
- orthopaedic surgery (1)
- overreaching markers (1)
- p38 MAPK (1)
- p53 (1)
- pain (1)
- pancreatic cancer (1)
- patent foramen ovale (1)
- pathology (1)
- pelvic injury (1)
- pelvic packing (1)
- platypnea (1)
- preoperative assessment (1)
- preoperative preparation (1)
- prostate brachytherapy (1)
- proteasome inhibitor (1)
- protein quality control (1)
- racket sports (1)
- radiotherapy (1)
- referred pain (1)
- reflexes (1)
- regulation (1)
- sEH (1)
- safety (1)
- soluble tumor necrosis factor receptor (1)
- sox genes (1)
- speech segmentation (1)
- spike train (1)
- strength and conditioning mesocycle (1)
- sulfur globules (1)
- temperature (1)
- temporal correlations (1)
- thiosulfate oxidation (1)
- tolerability (1)
- toxicity (1)
- transcatheter closure (1)
- trochee (1)
- tumor necrosis factor converting enzyme (1)
- ultrasound (1)
- viscero-cutaneous (1)
Institut
- Medizin (124) (entfernen)
Vacuum-assisted closure (VAC) of complex infected wounds has recently gained popularity among various surgical specialties. The system is based on the application of negative pressure by controlled suction to the wound surface. The effectiveness of the VAC System on microcirculation and the promotion of granulation tissue proliferation are proved. In our case report we illustrate a scenario were a patient developed severe bleeding from the ascending aorta by penetration of wire fragments in the vessel. We conclude that all free particles in the sternum have to be removed completely before negative pressure is used.
Background: Many cancer patients seek homeopathy as a complementary therapy. It has rarely been studied systematically, whether homeopathic care is of benefit for cancer patients. Methods: We conducted a prospective observational study with cancer patients in two differently treated cohorts: one cohort with patients under complementary homeopathic treatment (HG; n=259), and one cohort with conventionally treated cancer patients (CG; n=380). For a direct comparison, matched pairs with patients of the same tumour entity and comparable prognosis were to be formed. Main outcome parameter: change of quality of life (FACT-G, FACIT-Sp) after 3 months. Secondary outcome parameters: change of quality of life (FACT-G, FACIT-Sp) after a year, as well as impairment by fatigue (MFI) and by anxiety and depression (HADS). Results: HG: FACT-G, or FACIT-Sp, respectively improved statistically significantly in the first three months, from 75.6 (SD 14.6) to 81.1 (SD 16.9), or from 32.1 (SD 8.2) to 34.9 (SD 8.32), respectively. After 12 months, a further increase to 84.1 (SD 15.5) or 35.2 (SD 8.6) was found. Fatigue (MFI) decreased; anxiety and depression (HADS) did not change. CG: FACT-G remained constant in the first three months: 75.3 (SD 17.3) at t0, and 76.6 (SD 16.6) at t1. After 12 months, there was a slight increase to 78.9 (SD 18.1). FACIT-Sp scores improved significantly from t0 (31.0 - SD 8.9) to t1 (32.1 - SD 8.9) and declined again after a year (31.6 - SD 9.4). For fatigue, anxiety, and depression, no relevant changes were found. 120 patients of HG and 206 patients of CG met our criteria for matched-pairs selection. Due to large differences between the two patient populations, however, only 11 matched pairs could be formed. This is not sufficient for a comparative study. Conclusion: In our prospective study, we observed an improvement of quality of life as well as a tendency of fatigue symptoms to decrease in cancer patients under complementary homeopathic treatment. It would take considerably larger samples to find matched pairs suitable for comparison in order to establish a definite causal relation between these effects and homeopathic treatment.
HDL, through sphingosine-1-phosphate (S1P), exerts direct cardioprotective effects on ischemic myocardium. It remains unclear whether other HDL-associated sphingophospholipids have similar effects. We therefore examined if HDL-associated sphingosylphosphorylcholine (SPC) reduces infarct size in a mouse model of transient myocardial ischemia/reperfusion. Intravenously administered SPC dose-dependently reduced infarct size after 30 minutes of myocardial ischemia and 24 hours reperfusion compared to controls. Infarct size was also reduced by postischemic, therapeutical administration of SPC. Immunohistochemistry revealed reduced polymorphonuclear neutrophil recruitment to the infarcted area after SPC treatment, and apoptosis was attenuated as measured by TUNEL. In vitro, SPC inhibited leukocyte adhesion to TNFα-activated endothelial cells and protected rat neonatal cardiomyocytes from apoptosis. S1P3 was identified as the lysophospholipid receptor mediating the cardioprotection by SPC, since its effect was completely absent in S1P3-deficient mice. We conclude that HDL-associated SPC directly protects against myocardial reperfusion injury in vivo via the S1P3 receptor.
Forgotten features of head zones and their relation to diagnostically relevant acupuncture points
(2011)
In the 1890s Sir Henry Head discovered certain areas of the skin that develop tenderness (allodynia) in the course of visceral disease. These areas were later termed ‘Head zones’. In addition, he also emphasized the existence of specific points within these zones, that he called ‘maximum points’, a finding that seems to be almost forgotten today. We hypothesized that two important groups of acupuncture points, the diagnostically relevant Mu and Shu points, spatially and functionally coincide with these maximum points to a large extent. A comparison of Head's papers with the Huang Di Neijing (Yellow Thearch's Inner Classic) and the Zhen Jiu Jia Yi Jing (Systematic Classic of Acupuncture and Moxibustion), two of the oldest still extant Chinese sources on acupuncture, revealed astonishing parallels between the two concepts regarding both point locations and functional aspects. These findings suggest that the Chinese discovery of viscerocutaneous reflexes preceded the discovery in the West by more than 2000 years. Furthermore, the fact that Chinese medicine uses Mu and Shu points not only diagnostically but also therapeutically may give us new insights into the underlying mechanisms of acupuncture.