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Abstract Geant4 is a toolkit for simulating the passage of particles through matter. It includes a complete range of functionality including tracking, geometry, physics models and hits. The physics processes offered cover a comprehensive range, including electromagnetic, hadronic and optical processes, a large set of long-lived particles, materials and elements, over a wide energy range starting, in some cases, from 250 eV and extending in others to the TeV energy range. It has been designed and constructed to expose the physics models utilised, to handle complex geometries, and to enable its easy adaptation for optimal use in different sets of applications. The toolkit is the result of a worldwide collaboration of physicists and software engineers. It has been created exploiting software engineering and object-oriented technology and implemented in the C++ programming language. It has been used in applications in particle physics, nuclear physics, accelerator design, space engineering and medical physics. PACS: 07.05.Tp; 13; 23
Ausgangsfragen: Bologna: Segen und/oder Fluch? Bedeuten Modularisierung und Ausrichtung auf Kompetenzen das Ende der Humboldt'schen Bildungsidee? Und wenn: Ist das ein Verlust oder ein Gewinn? Wie ist die Modularisierung der Studienordnung mit Blick auf praktische Erfahrungen zu bewerten? Hat sie zu einer Verbesserung des Studienverlaufs geführt? Welches Curriculum müsste die Germanistik der Zukunft haben? Welche 'Schlüsselqualifikationen' sollte sie vermitteln? Sollte das Studium (noch) stärker berufsorientiert strukturiert sein? Sind auch hier Anpassungen an das medientechnische Umfeld erforderlich? Wie steht es generell um die Berufsaussichten von Germanisten? Kommt den Fächern bzw. den Universitäten selbst eine höhere Verantwortung für die Vermittlung in Berufe zu ('employability')?
We study various fluctuation and correlation signals of the deconfined state using a dynamical recombination approach (quark Molecular Dynamics, qMD). We analyse charge ratio fluctuations, charge transfer fluctuations and baryon-strangeness correlations as a function of the center of mass energy with a set of central Pb+Pb/Au+Au events from AGS energies on (Elab = 4 AGeV) up to the highest RHIC energy available (V sNN = 200 GeV) and as a function of time with a set of central Au+Au qMD events at V sNN = 200 GeV with and without applying our hadronization procedure. For all studied quantities, the results start from values compatible with a weakly coupled QGP in the early stage and end with values compatible with the hadronic result in the final state. We show that the loss of the signal occurs at the same time as hadronization and trace it back to the dynamical recombination process implemented in our model.
Within a dynamical quark recombination model, we explore various proposed event-by-event observables sensitive to the microscopic structure of the QCD-matter created at RHIC energies. Charge ratio fluctuations, charge transfer fluctuations and baryon-strangeness correlations are computed from a sample of central Au + Au events at the highest RHIC energy available (sNN=200 GeV). We find that for all explored observables, the calculations yield the values predicted for a quark–gluon plasma only at early times of the evolution, whereas the final state approaches the values expected for a hadronic gas. We argue that the recombination-like hadronization process itself is responsible for the disappearance of the predicted deconfinement signals. This might explain why no fluctuation signatures for the transition between quark and hadronic matter was ever observed in the experimental data up to now.
A microscopic model of deconfined matter based on color interactions between semi-classical quarks is studied. A hadronization mechanism is imposed to examine the properties and the disassembly of a thermalized quark plasma and to investigate the possible existence of a phase transition from quark matter to hadron matter.
We investigate the hadronic cooling of a quark droplet within a microscopic model. The color flux tube approach is used to describe the hadronization of the quark phase. The model reproduces experimental particle ratios equally well compared to a static thermal hadronic source. Furthermore, the dynamics of the decomposition of a quark-gluon plasma is investigated and time dependent particle ratios are found.
String theory suggests the existence of a minimum length scale. An exciting quantum mechanical implication of this feature is a modification of the uncertainty principle. In contrast to the conventional approach, this generalised uncertainty principle does not allow to resolve space–time distances below the Planck length. In models with extra dimensions, which are also motivated by string theory, the Planck scale can be lowered to values accessible by ultra high energetic cosmic rays (UHECRs) and by future colliders, i.e., Mf≈ 1 TeV. It is demonstrated that in this novel scenario, short distance physics below 1/Mf is completely cloaked by the uncertainty principle. Therefore, Planckian effects could be the final physics discovery at future colliders and in UHECRs. As an application, we predict the modifications to the e+e−→f+f− cross-sections.
String theory suggests the existence of a minimum length scale. An exciting quantum mechanical implication of this feature is a modification of the uncertainty principle. In contrast to the conventional approach, this generalised uncertainty principle does not allow to resolve space time distances below the Planck length. In models with extra dimensions, which are also motivated by string theory, the Planck scale can be lowered to values accessible by ultra high energetic cosmic rays (UHECRs) and by future colliders, i.e. M f approximately equal to 1 TeV. It is demonstrated that in this novel scenario, short distance physics below 1/M f is completely cloaked by the uncertainty principle. Therefore, Planckian effects could be the final physics discovery at future colliders and in UHECRs. As an application, we predict the modifications to the e+ e- to f+ f- cross-sections.
Purpose: While more advanced COVID-19 necessitates medical interventions and hospitalization, patients with mild COVID-19 do not require this. Identifying patients at risk of progressing to advanced COVID-19 might guide treatment decisions, particularly for better prioritizing patients in need for hospitalization.
Methods: We developed a machine learning-based predictor for deriving a clinical score identifying patients with asymptomatic/mild COVID-19 at risk of progressing to advanced COVID-19. Clinical data from SARS-CoV-2 positive patients from the multicenter Lean European Open Survey on SARS-CoV-2 Infected Patients (LEOSS) were used for discovery (2020-03-16 to 2020-07-14) and validation (data from 2020-07-15 to 2021-02-16).
Results: The LEOSS dataset contains 473 baseline patient parameters measured at the first patient contact. After training the predictor model on a training dataset comprising 1233 patients, 20 of the 473 parameters were selected for the predictor model. From the predictor model, we delineated a composite predictive score (SACOV-19, Score for the prediction of an Advanced stage of COVID-19) with eleven variables. In the validation cohort (n = 2264 patients), we observed good prediction performance with an area under the curve (AUC) of 0.73 ± 0.01. Besides temperature, age, body mass index and smoking habit, variables indicating pulmonary involvement (respiration rate, oxygen saturation, dyspnea), inflammation (CRP, LDH, lymphocyte counts), and acute kidney injury at diagnosis were identified. For better interpretability, the predictor was translated into a web interface.
Conclusion: We present a machine learning-based predictor model and a clinical score for identifying patients at risk of developing advanced COVID-19.
Das Internationale Colloquium "Perspektiven der Germanistik im 21. Jahrhundert" fand vom 4. bis 6. April 2013 im SchlossHerrenhausen in Hannover statt.
Der Autor hat den Herausgebern den vorliegenden Text nach der Konferenz zur Verfügung gestellt. Er antwortet auf die Ausgangsfragen zum Diskussionsforum B.2 "Germanistik studieren – Perspektiven in Ausbildung und Beruf", die im Programm zur Veranstaltung formuliert worden waren.